Click here to switch to the map view.

The map label for this gene is fadL [H]

Identifier: 59712150

GI number: 59712150

Start: 1726441

End: 1727784

Strand: Reverse

Name: fadL [H]

Synonym: VF_1543

Alternate gene names: 59712150

Gene position: 1727784-1726441 (Counterclockwise)

Preceding gene: 59712152

Following gene: 59712149

Centisome position: 59.63

GC content: 36.76

Gene sequence:

>1344_bases
ATGAATACAACATTTTCGCGTACGCTGCTTGCAACAAGTACTTTATTTATTAGTGCGACATCTATAGCTGGAGGATTTCA
AGTAAACGAACATTCAGCTACAGGTTTAGGTCGAGCGTTTGCAGGTGAGGCGGTTATTGCAGATAACGCTTCAGTATTAA
GTCGTAATGCGGCGGCAATGACGATGTTTGATTCAACATCCATTTCAATGGGGTTAACTATGGTTAAGCCTGATGTAAGT
GTGGAAAATGTAGAATATCAACAACTGAAAATTAATGAAAATATGGGGATTCCGACAGGAATAGGATTCAACAGTATGAC
GGTTTCTAATACTGATGGGATTGCAGGAACGGAGTTTGTTCCAAATTTTTATGTAATTCACCCCTTAAATGATAAATGGG
CATTTGGATTCGCAAGTTATTCTAATTTTGGGACAGGCACAGAATTTGAGGATAACTATGATGCTTCTATTTTTGGTGGG
AAAACAGAGGTAAAAAGTGCCAATATCGGTTTTAGTTTGGCATATAAGCTTAATGAACAATGGAGTTTTGGTGCTGGAAT
TGATGTTATTTATGGTATTGGTAATTTATATCGGGATCTTGACAGTACGATTTGTAATAAGCCTTTTGCGGGAGCAAAAG
ATTGTTCTATTAAGAAAACTAAAGCCTTGGATATATCAGCTACTGGTGTAGGCATTGGCGGGAATGTTGGTGTTGTATAT
CAGGTTAATGAGCGCAATCGTTTTGGTTTAAGTTATAAATACAGTCCAGAAGTTGAAGCGGAAGGTGATGTTGATTATTT
AGAGAATCATGTACATGGCGTGACAAGTGATAGTGTGTATTTACCGCTACCTGATATTGCTGAATTTTCGGGTTATCATT
TACTAACCGATAAAGTGGCAATCCATTATAGTTATCAGTGGATTGGTTGGTCTGCATTTGATTCTGTTGATATTAATGAT
GTTAATTCTGATCAACGTATTTCGGTAAAAGAATACAATTGGAAAAACTCATATCATATCGCTGTAGGTACAACTTATTA
CTTAAATAAAAAATGGACATTACGTGCAGGCTATATGTTTGATAAAACGCCAGTAGATGAAATTACGTCAATTTCGATTC
CTGATTCAGATAGACAATGGTTTTCAACTGGTTTCACTTATAACTGGAGTAACCAAACCAGCGTAGATTTTGGTTTTACG
TATTTAATTGGTGAAGATGTTGAGGTTTCAGAGGTTCAAGATATTCCGGATATGATGGGCATTACTACGCCTAATCCATC
TTTAACTGCAACCACACACGCTAATGCTGTGTTAGCCGCTATTCAATTGAGTCATAGTTTCTAA

Upstream 100 bases:

>100_bases
CTGTTACACTTTTTTTCCTAAAAAATAACACAGCAAATTTCAGACATTTCCTTTTAAATAAAGTTCGGTTTGATTTGTCC
AAAGTGGATATAACACAATT

Downstream 100 bases:

>100_bases
AATAACTCATAAAATTGCTATGCACCTCAATGATTCAAGGCTCTGATTATTCCGAGCCTTTTTTTTGTTTAGCAAACATG
CTCTAATTACGCCTCATTTC

Product: long-chain fatty acid transport protein precursor

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MNTTFSRTLLATSTLFISATSIAGGFQVNEHSATGLGRAFAGEAVIADNASVLSRNAAAMTMFDSTSISMGLTMVKPDVS
VENVEYQQLKINENMGIPTGIGFNSMTVSNTDGIAGTEFVPNFYVIHPLNDKWAFGFASYSNFGTGTEFEDNYDASIFGG
KTEVKSANIGFSLAYKLNEQWSFGAGIDVIYGIGNLYRDLDSTICNKPFAGAKDCSIKKTKALDISATGVGIGGNVGVVY
QVNERNRFGLSYKYSPEVEAEGDVDYLENHVHGVTSDSVYLPLPDIAEFSGYHLLTDKVAIHYSYQWIGWSAFDSVDIND
VNSDQRISVKEYNWKNSYHIAVGTTYYLNKKWTLRAGYMFDKTPVDEITSISIPDSDRQWFSTGFTYNWSNQTSVDFGFT
YLIGEDVEVSEVQDIPDMMGITTPNPSLTATTHANAVLAAIQLSHSF

Sequences:

>Translated_447_residues
MNTTFSRTLLATSTLFISATSIAGGFQVNEHSATGLGRAFAGEAVIADNASVLSRNAAAMTMFDSTSISMGLTMVKPDVS
VENVEYQQLKINENMGIPTGIGFNSMTVSNTDGIAGTEFVPNFYVIHPLNDKWAFGFASYSNFGTGTEFEDNYDASIFGG
KTEVKSANIGFSLAYKLNEQWSFGAGIDVIYGIGNLYRDLDSTICNKPFAGAKDCSIKKTKALDISATGVGIGGNVGVVY
QVNERNRFGLSYKYSPEVEAEGDVDYLENHVHGVTSDSVYLPLPDIAEFSGYHLLTDKVAIHYSYQWIGWSAFDSVDIND
VNSDQRISVKEYNWKNSYHIAVGTTYYLNKKWTLRAGYMFDKTPVDEITSISIPDSDRQWFSTGFTYNWSNQTSVDFGFT
YLIGEDVEVSEVQDIPDMMGITTPNPSLTATTHANAVLAAIQLSHSF
>Mature_447_residues
MNTTFSRTLLATSTLFISATSIAGGFQVNEHSATGLGRAFAGEAVIADNASVLSRNAAAMTMFDSTSISMGLTMVKPDVS
VENVEYQQLKINENMGIPTGIGFNSMTVSNTDGIAGTEFVPNFYVIHPLNDKWAFGFASYSNFGTGTEFEDNYDASIFGG
KTEVKSANIGFSLAYKLNEQWSFGAGIDVIYGIGNLYRDLDSTICNKPFAGAKDCSIKKTKALDISATGVGIGGNVGVVY
QVNERNRFGLSYKYSPEVEAEGDVDYLENHVHGVTSDSVYLPLPDIAEFSGYHLLTDKVAIHYSYQWIGWSAFDSVDIND
VNSDQRISVKEYNWKNSYHIAVGTTYYLNKKWTLRAGYMFDKTPVDEITSISIPDSDRQWFSTGFTYNWSNQTSVDFGFT
YLIGEDVEVSEVQDIPDMMGITTPNPSLTATTHANAVLAAIQLSHSF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=440, Percent_Identity=33.8636363636364, Blast_Score=248, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 48964; Mature: 48964

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTFSRTLLATSTLFISATSIAGGFQVNEHSATGLGRAFAGEAVIADNASVLSRNAAAM
CCCCHHHHHEEEEEEEEEEEECCCCEEECCCCCCCCCHHHCCCEEEECCHHHHCCCCEEE
TMFDSTSISMGLTMVKPDVSVENVEYQQLKINENMGIPTGIGFNSMTVSNTDGIAGTEFV
EEECCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCEEC
PNFYVIHPLNDKWAFGFASYSNFGTGTEFEDNYDASIFGGKTEVKSANIGFSLAYKLNEQ
CCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCEEEECCCCEEEEEEECCC
WSFGAGIDVIYGIGNLYRDLDSTICNKPFAGAKDCSIKKTKALDISATGVGIGGNVGVVY
CCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEE
QVNERNRFGLSYKYSPEVEAEGDVDYLENHVHGVTSDSVYLPLPDIAEFSGYHLLTDKVA
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEECCCCHHHCCCEEEEEEEEE
IHYSYQWIGWSAFDSVDINDVNSDQRISVKEYNWKNSYHIAVGTTYYLNKKWTLRAGYMF
EEEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEECCEEEEEECEEE
DKTPVDEITSISIPDSDRQWFSTGFTYNWSNQTSVDFGFTYLIGEDVEVSEVQDIPDMMG
CCCCHHHHEEEECCCCCCHHEECCCEEECCCCCEEEEEEEEEECCCCCHHHHHCCHHHHC
ITTPNPSLTATTHANAVLAAIQLSHSF
CCCCCCCEEEECCCCEEEEEEEEECCC
>Mature Secondary Structure
MNTTFSRTLLATSTLFISATSIAGGFQVNEHSATGLGRAFAGEAVIADNASVLSRNAAAM
CCCCHHHHHEEEEEEEEEEEECCCCEEECCCCCCCCCHHHCCCEEEECCHHHHCCCCEEE
TMFDSTSISMGLTMVKPDVSVENVEYQQLKINENMGIPTGIGFNSMTVSNTDGIAGTEFV
EEECCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCEEC
PNFYVIHPLNDKWAFGFASYSNFGTGTEFEDNYDASIFGGKTEVKSANIGFSLAYKLNEQ
CCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCEEEECCCCEEEEEEECCC
WSFGAGIDVIYGIGNLYRDLDSTICNKPFAGAKDCSIKKTKALDISATGVGIGGNVGVVY
CCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEE
QVNERNRFGLSYKYSPEVEAEGDVDYLENHVHGVTSDSVYLPLPDIAEFSGYHLLTDKVA
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEECCCCHHHCCCEEEEEEEEE
IHYSYQWIGWSAFDSVDINDVNSDQRISVKEYNWKNSYHIAVGTTYYLNKKWTLRAGYMF
EEEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEECCEEEEEECEEE
DKTPVDEITSISIPDSDRQWFSTGFTYNWSNQTSVDFGFTYLIGEDVEVSEVQDIPDMMG
CCCCHHHHEEEECCCCCCHHEECCCEEECCCCCEEEEEEEEEECCCCCHHHHHCCHHHHC
ITTPNPSLTATTHANAVLAAIQLSHSF
CCCCCCCEEEECCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]