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The map label for this gene is udp [H]

Identifier: 59712128

GI number: 59712128

Start: 1699689

End: 1700447

Strand: Reverse

Name: udp [H]

Synonym: VF_1521

Alternate gene names: 59712128

Gene position: 1700447-1699689 (Counterclockwise)

Preceding gene: 59712129

Following gene: 59712126

Centisome position: 58.69

GC content: 43.48

Gene sequence:

>759_bases
ATGACAGCAGCAGTATTCCATTTAGGCGTAACAAAAGAAGATCTTCAAGGTGCAGAAATGGCGATCATCCCTGGTGATCC
AGCACGCGTTCAGAAAATCGCAGAACAAATGGAAAACCCTAAGTTTTTAGCAAGCCACCGTGAATACACAGTGTACTTAG
CTGAGCTAGATGGCAAGAAGATTGTGGTATGTTCTACAGGTATTGGTGGTCCATCAACATCTATTGCGGTTGAAGAACTT
GCTCAATTAGGTGTTCGTACTTTCCTACGTGTAGGTACAACTGGTGCAATTCAACCTCATGTGAATGTAGGTGATATGAT
TGTTACTACAGGTTCAGTTCGTTTAGATGGTGCGAGTCTTCATTTTGCTCCAATGGAATTCCCAGCAGTTGCTGACTTTG
ACGTTGCAACAGCAATGCGTAAAGCGGTAGTTGACCAAGGTGCAAATGTACACACAGGTGTAACAGCATCAAGTGATACC
TTCTACCCGGGTCAAGAGCGTTACGACACGTTCTCTGGTCGTGTTGTTAAGCGTTTCCAAGGCTCTATGCAAGAATGGCA
AGACATGGGCGTACTGAACTTTGAAATGGAATCAGCGACGTTATTAACTATGTGTGCAAGCTCTGGTTTACGTGCAGGTT
GTGTTGCGGGTGTAATTATTAACCGTACTCAAAAAGAAATCCCAGATCACGCAACGCTAAAAGAAACAGAAGCGCGTTCA
ATTAAAGTGGTAATTGAAGCTGCTCGAAATCTTCTATAA

Upstream 100 bases:

>100_bases
TTGTCACATAAAGCTGTCATTTAATTGGGTAGAGTAGCTACATCAAATCAAATATAACTAATTTAATTAACGCGGCCCTA
CAAACCGCAAGGAGCTAACC

Downstream 100 bases:

>100_bases
TAGGAAGAGCACAAAGAAATATAGAGTGCCGCTGGTTCATAGTGAATCAGCGGCATTTTTATATGAATTGAAAAGCATTA
AAAAAGGCCCACAGCAGGAT

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTAAVFHLGVTKEDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELDGKKIVVCSTGIGGPSTSIAVEEL
AQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVADFDVATAMRKAVVDQGANVHTGVTASSDT
FYPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKEIPDHATLKETEARS
IKVVIEAARNLL

Sequences:

>Translated_252_residues
MTAAVFHLGVTKEDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELDGKKIVVCSTGIGGPSTSIAVEEL
AQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVADFDVATAMRKAVVDQGANVHTGVTASSDT
FYPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKEIPDHATLKETEARS
IKVVIEAARNLL
>Mature_251_residues
TAAVFHLGVTKEDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELDGKKIVVCSTGIGGPSTSIAVEELA
QLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVADFDVATAMRKAVVDQGANVHTGVTASSDTF
YPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKEIPDHATLKETEARSI
KVVIEAARNLL

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=248, Percent_Identity=74.1935483870968, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=29.4871794871795, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27088; Mature: 26957

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVFHLGVTKEDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELDGKK
CCEEEEEECCCHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEECCCEEEEEEEECCCCE
IVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEECCCEE
HFAPMEFPAVADFDVATAMRKAVVDQGANVHTGVTASSDTFYPGQERYDTFSGRVVKRFQ
EECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCEECCCCCCCCCHHHHHHHHHHHHHHHH
GSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKEIPDHATLKETEARS
HHHHHHHHCCCEEEECCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHH
IKVVIEAARNLL
HHHHHHHHHHCC
>Mature Secondary Structure 
TAAVFHLGVTKEDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELDGKK
CEEEEEECCCHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEECCCEEEEEEEECCCCE
IVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEECCCEE
HFAPMEFPAVADFDVATAMRKAVVDQGANVHTGVTASSDTFYPGQERYDTFSGRVVKRFQ
EECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCEECCCCCCCCCHHHHHHHHHHHHHHHH
GSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKEIPDHATLKETEARS
HHHHHHHHCCCEEEECCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHH
IKVVIEAARNLL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]