Click here to switch to the map view.

The map label for this gene is qseD [H]

Identifier: 59712117

GI number: 59712117

Start: 1683687

End: 1684586

Strand: Direct

Name: qseD [H]

Synonym: VF_1510

Alternate gene names: 59712117

Gene position: 1683687-1684586 (Clockwise)

Preceding gene: 59712114

Following gene: 59712120

Centisome position: 58.11

GC content: 33.11

Gene sequence:

>900_bases
GTGTTTGAATTTAAATGGTTAGAAGACTTTATGAGTCTAATTGAACTAGGGAATTTCTCTGCTGCTGCTAAATCAAGATA
CGTAACACAATCTGCATTTAGCCGTCGAATTCAAGCCTTGGAGCTTTGGGTTGGTGTTCCATTGTTTGATCGTAGTTCTT
ACCCTATAGGCTTAACCGAGCACGGAAATAAATTTGTCCCTTATGCTGAAAACCTACTTAACCAAATCAAAGTAACAAAA
GAGGATTTTTCATTAGCTTCATTAAAAACAGACAATACGGTACGAATTGTTTGTTTACATTCCTTTGCGATTAATCTATT
ACCAAATCTTTTGGCGCAATTTAATAACCAACTAAGTCATCTCAACATATCTATTAATCCTTCTGTTCAAGGTATCGATA
ATCACTTTCAAACTCTATTAGATGATTCAAGTGACCTTTTATTTACTTATAATATGATCGGAATGAGACCATCTATTTCC
TTAGAAAATAAATTAGAAAAACATATTTTATTTAAGGAAAAAATTATTCCTGTTATCTCTCCGGATTTATTAAAAAATCA
TGAAGATAATACTCCATGGCCATTACTCTCTTATTCAGAACATACATTTCTCTACAAAGTAGTAAATCAACTTACAAAAT
CTATTTCAGTACCTTTCAGTCAAGTCTTTGAAACAACGTTAAGCGAATCTCTCATTGAAATGGCGATTAATGGTATCGGG
GTTGCTTGGGTTCCAATGCATGCGGTTGAAAAAGAATTAATTAAGGGGACATTAGTGACAGCCTTTACAGAATACTCTGA
TTGGACTATTCAGTTAGATGTTGTTTGCTATCATTCGAAAGCTAATAGTCGTCCTGCTGTACTGCAATTTTTAGAAGAAA
TACATAGCTTGAAAAATTAA

Upstream 100 bases:

>100_bases
ACAATAATAACCATATAAAAAATGTGAGTATCTCGATTTCTATTGCTAATTTTGAATGATAGTATTCTTATAAATCATAA
TGATAAAGATGAGTTGTTAA

Downstream 100 bases:

>100_bases
AGGTGGCCAATCTAAGCCACCTTTTTTGTTTTTAATTCAGCGCCTTTGCAATTACCATATCACGATGAATTCGTGCTTTT
TCAACCTCAGTTGTTGCCTT

Product: transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MFEFKWLEDFMSLIELGNFSAAAKSRYVTQSAFSRRIQALELWVGVPLFDRSSYPIGLTEHGNKFVPYAENLLNQIKVTK
EDFSLASLKTDNTVRIVCLHSFAINLLPNLLAQFNNQLSHLNISINPSVQGIDNHFQTLLDDSSDLLFTYNMIGMRPSIS
LENKLEKHILFKEKIIPVISPDLLKNHEDNTPWPLLSYSEHTFLYKVVNQLTKSISVPFSQVFETTLSESLIEMAINGIG
VAWVPMHAVEKELIKGTLVTAFTEYSDWTIQLDVVCYHSKANSRPAVLQFLEEIHSLKN

Sequences:

>Translated_299_residues
MFEFKWLEDFMSLIELGNFSAAAKSRYVTQSAFSRRIQALELWVGVPLFDRSSYPIGLTEHGNKFVPYAENLLNQIKVTK
EDFSLASLKTDNTVRIVCLHSFAINLLPNLLAQFNNQLSHLNISINPSVQGIDNHFQTLLDDSSDLLFTYNMIGMRPSIS
LENKLEKHILFKEKIIPVISPDLLKNHEDNTPWPLLSYSEHTFLYKVVNQLTKSISVPFSQVFETTLSESLIEMAINGIG
VAWVPMHAVEKELIKGTLVTAFTEYSDWTIQLDVVCYHSKANSRPAVLQFLEEIHSLKN
>Mature_299_residues
MFEFKWLEDFMSLIELGNFSAAAKSRYVTQSAFSRRIQALELWVGVPLFDRSSYPIGLTEHGNKFVPYAENLLNQIKVTK
EDFSLASLKTDNTVRIVCLHSFAINLLPNLLAQFNNQLSHLNISINPSVQGIDNHFQTLLDDSSDLLFTYNMIGMRPSIS
LENKLEKHILFKEKIIPVISPDLLKNHEDNTPWPLLSYSEHTFLYKVVNQLTKSISVPFSQVFETTLSESLIEMAINGIG
VAWVPMHAVEKELIKGTLVTAFTEYSDWTIQLDVVCYHSKANSRPAVLQFLEEIHSLKN

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=305, Percent_Identity=30.1639344262295, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789173, Length=272, Percent_Identity=27.9411764705882, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788481, Length=259, Percent_Identity=25.8687258687259, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789440, Length=272, Percent_Identity=24.2647058823529, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081904, Length=268, Percent_Identity=24.2537313432836, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI145693105, Length=150, Percent_Identity=28.6666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=262, Percent_Identity=22.9007633587786, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34067; Mature: 34067

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEFKWLEDFMSLIELGNFSAAAKSRYVTQSAFSRRIQALELWVGVPLFDRSSYPIGLTE
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEECC
HGNKFVPYAENLLNQIKVTKEDFSLASLKTDNTVRIVCLHSFAINLLPNLLAQFNNQLSH
CCCEECCHHHHHHHHHCCCHHCCCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHCCCCEE
LNISINPSVQGIDNHFQTLLDDSSDLLFTYNMIGMRPSISLENKLEKHILFKEKIIPVIS
EEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
PDLLKNHEDNTPWPLLSYSEHTFLYKVVNQLTKSISVPFSQVFETTLSESLIEMAINGIG
HHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
VAWVPMHAVEKELIKGTLVTAFTEYSDWTIQLDVVCYHSKANSRPAVLQFLEEIHSLKN
EEEHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFEFKWLEDFMSLIELGNFSAAAKSRYVTQSAFSRRIQALELWVGVPLFDRSSYPIGLTE
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEECC
HGNKFVPYAENLLNQIKVTKEDFSLASLKTDNTVRIVCLHSFAINLLPNLLAQFNNQLSH
CCCEECCHHHHHHHHHCCCHHCCCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHCCCCEE
LNISINPSVQGIDNHFQTLLDDSSDLLFTYNMIGMRPSISLENKLEKHILFKEKIIPVIS
EEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
PDLLKNHEDNTPWPLLSYSEHTFLYKVVNQLTKSISVPFSQVFETTLSESLIEMAINGIG
HHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
VAWVPMHAVEKELIKGTLVTAFTEYSDWTIQLDVVCYHSKANSRPAVLQFLEEIHSLKN
EEEHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]