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The map label for this gene is dcuD [H]

Identifier: 59712115

GI number: 59712115

Start: 1680886

End: 1682346

Strand: Reverse

Name: dcuD [H]

Synonym: VF_1508

Alternate gene names: 59712115

Gene position: 1682346-1680886 (Counterclockwise)

Preceding gene: 59712116

Following gene: 59712113

Centisome position: 58.06

GC content: 35.46

Gene sequence:

>1461_bases
ATGAGTTTATTTATTGCATTATGTGGGTTGATTCTTGCGGGAAGATTAATTTTAAAAAACTATAACCCCCAAGGCGTACT
CTTCTTTGTTGGTATCGTTATGATGACCATATCAATCTTTACTAACAATGCTACTTTTGTCGATAAATCGACGGGTTGGA
TAGGGTTTGATGTTTTTGAATATATAAGCATGGTTTTTGGCAAACAATCCGGTGGTTTAGGTTTAAAAATAATGCTTATA
GGAGGGTTTGCCTTATTAATGTCAGCTATAGGAGCAAGCCAAGTAATGGTAAAGTTAACAGCTAAGCCATTAATGAAGCT
AAATTCACCTTACTTGATGCTAGCACTTGCCTTTATTCTTGGTCAGATGTTATCACTCTTTATCTCAAGCGCAACGGGAC
TTGGTTTATTGTTGATGGCAACACTTTATCCTGTATTGATTAGACTGGGCTGTAGTAAAGCGGGTGTTGCTTCTGTATTA
GCGAGTACTTGCGCTATTGAGTTTGGTCCTGGTTCAGGAAACTCAATTTTAGCTGCTCAAACCGCTGGTCTAGAGATTAC
GGAATACTTTGTTGGGGAACAATTACCAATTATTAGCGTATTGATTATAGTTGTGGCAATTATGCATGCAATTACACAAC
GTTTTTTTGACCGTAATGACGAAAAAAATCAGACATTAGAGCCAATAAATTATGAAGATATTGAATCGGAACAAAGTGCT
CCCTTCTATTATGTAATACTTCCAATGTTACCATTATTTTTTATGCTTACATTTAGTAGCCTTGGCGTGAAGACAATTAA
TGTGGGTATGGCAACTGCTATCATTTTGAGTATTTTTATTAGCCTTGTATTTGAATTTATTCGAGAAAGAGAAGTAAAAC
CTGTATTTGAAAAACTACAAGGAGTATTTGATGATATGGGAAAAGTTTTTGCTTCTGTTGTAACTTTAATTATAGCAGGC
CAGACTTTTTCTATGGGATTAAAGTCAATAGGAGCTATTGATTCAATGTTACATATGGCAAGTAGCGTTGGGCTTTCTGC
TGCTGTTATTATTTTGTTTATGGCTCTATTAACTTTCATTATTTCTGCATTAATGGGATCAGGGAATGCGGCCTTTTTCT
CTTTTGCTCCAATGGTGCCCCAAATTGCTCATAAAATAGGTGCGAATACTGTAGATATGATCTTACCAATTCAATTATCT
GCAGGTTTTGGTAGAACAATATCTCCGATTGCAGGTGTTATCATTGCTGTTGCCGGTATTTCAGGTTTGTCTCCATTTGA
TATAGTTCGTCGAACTTTGATACCAATGGTAAGTGGTTGGTTATTAATGCTAATTTTAACTTTTTCTAAGGGAGGACAAT
TAGAGCAATTAATGCCATTTTTGATTGTAATATTAGTTCTTTCTGTTGGTGTCGGTTGGATAATGAAGAGAAAGAATAAT
AGAACACAATTGACTCAGTAA

Upstream 100 bases:

>100_bases
AACGATGACTTTACACTTTATGGGGTAGTAGCAAAAGGTAAAACAGTACTGCTTGATAATGAATTACTTGTAACTGGAAA
CTTTGAATAAGGGATTAGAT

Downstream 100 bases:

>100_bases
CTTAATAGACATTAAAAACAAAAAGGTGGTCATAATTGACCACCTTTATTTTTATCATTAAAGATAAAATAAACCTTATA
AGTAAAGCTTAGCTAAATCG

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MSLFIALCGLILAGRLILKNYNPQGVLFFVGIVMMTISIFTNNATFVDKSTGWIGFDVFEYISMVFGKQSGGLGLKIMLI
GGFALLMSAIGASQVMVKLTAKPLMKLNSPYLMLALAFILGQMLSLFISSATGLGLLLMATLYPVLIRLGCSKAGVASVL
ASTCAIEFGPGSGNSILAAQTAGLEITEYFVGEQLPIISVLIIVVAIMHAITQRFFDRNDEKNQTLEPINYEDIESEQSA
PFYYVILPMLPLFFMLTFSSLGVKTINVGMATAIILSIFISLVFEFIREREVKPVFEKLQGVFDDMGKVFASVVTLIIAG
QTFSMGLKSIGAIDSMLHMASSVGLSAAVIILFMALLTFIISALMGSGNAAFFSFAPMVPQIAHKIGANTVDMILPIQLS
AGFGRTISPIAGVIIAVAGISGLSPFDIVRRTLIPMVSGWLLMLILTFSKGGQLEQLMPFLIVILVLSVGVGWIMKRKNN
RTQLTQ

Sequences:

>Translated_486_residues
MSLFIALCGLILAGRLILKNYNPQGVLFFVGIVMMTISIFTNNATFVDKSTGWIGFDVFEYISMVFGKQSGGLGLKIMLI
GGFALLMSAIGASQVMVKLTAKPLMKLNSPYLMLALAFILGQMLSLFISSATGLGLLLMATLYPVLIRLGCSKAGVASVL
ASTCAIEFGPGSGNSILAAQTAGLEITEYFVGEQLPIISVLIIVVAIMHAITQRFFDRNDEKNQTLEPINYEDIESEQSA
PFYYVILPMLPLFFMLTFSSLGVKTINVGMATAIILSIFISLVFEFIREREVKPVFEKLQGVFDDMGKVFASVVTLIIAG
QTFSMGLKSIGAIDSMLHMASSVGLSAAVIILFMALLTFIISALMGSGNAAFFSFAPMVPQIAHKIGANTVDMILPIQLS
AGFGRTISPIAGVIIAVAGISGLSPFDIVRRTLIPMVSGWLLMLILTFSKGGQLEQLMPFLIVILVLSVGVGWIMKRKNN
RTQLTQ
>Mature_485_residues
SLFIALCGLILAGRLILKNYNPQGVLFFVGIVMMTISIFTNNATFVDKSTGWIGFDVFEYISMVFGKQSGGLGLKIMLIG
GFALLMSAIGASQVMVKLTAKPLMKLNSPYLMLALAFILGQMLSLFISSATGLGLLLMATLYPVLIRLGCSKAGVASVLA
STCAIEFGPGSGNSILAAQTAGLEITEYFVGEQLPIISVLIIVVAIMHAITQRFFDRNDEKNQTLEPINYEDIESEQSAP
FYYVILPMLPLFFMLTFSSLGVKTINVGMATAIILSIFISLVFEFIREREVKPVFEKLQGVFDDMGKVFASVVTLIIAGQ
TFSMGLKSIGAIDSMLHMASSVGLSAAVIILFMALLTFIISALMGSGNAAFFSFAPMVPQIAHKIGANTVDMILPIQLSA
GFGRTISPIAGVIIAVAGISGLSPFDIVRRTLIPMVSGWLLMLILTFSKGGQLEQLMPFLIVILVLSVGVGWIMKRKNNR
TQLTQ

Specific function: May have a role in the transport of dicarboxylates from the periplasm across the inner membrane. Seems not to be essential for growth. It is likely to be a cryptic gene, as no or low expression has been found under a number of growth conditions and when t

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1789622, Length=457, Percent_Identity=39.8249452954048, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1786839, Length=388, Percent_Identity=36.8556701030928, Blast_Score=236, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 52331; Mature: 52200

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFIALCGLILAGRLILKNYNPQGVLFFVGIVMMTISIFTNNATFVDKSTGWIGFDVFE
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
YISMVFGKQSGGLGLKIMLIGGFALLMSAIGASQVMVKLTAKPLMKLNSPYLMLALAFIL
HHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GQMLSLFISSATGLGLLLMATLYPVLIRLGCSKAGVASVLASTCAIEFGPGSGNSILAAQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCEEEEE
TAGLEITEYFVGEQLPIISVLIIVVAIMHAITQRFFDRNDEKNQTLEPINYEDIESEQSA
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCC
PFYYVILPMLPLFFMLTFSSLGVKTINVGMATAIILSIFISLVFEFIREREVKPVFEKLQ
CEEEEHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GVFDDMGKVFASVVTLIIAGQTFSMGLKSIGAIDSMLHMASSVGLSAAVIILFMALLTFI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ISALMGSGNAAFFSFAPMVPQIAHKIGANTVDMILPIQLSAGFGRTISPIAGVIIAVAGI
HHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCC
SGLSPFDIVRRTLIPMVSGWLLMLILTFSKGGQLEQLMPFLIVILVLSVGVGWIMKRKNN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCC
RTQLTQ
CCCCCC
>Mature Secondary Structure 
SLFIALCGLILAGRLILKNYNPQGVLFFVGIVMMTISIFTNNATFVDKSTGWIGFDVFE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
YISMVFGKQSGGLGLKIMLIGGFALLMSAIGASQVMVKLTAKPLMKLNSPYLMLALAFIL
HHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GQMLSLFISSATGLGLLLMATLYPVLIRLGCSKAGVASVLASTCAIEFGPGSGNSILAAQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCEEEEE
TAGLEITEYFVGEQLPIISVLIIVVAIMHAITQRFFDRNDEKNQTLEPINYEDIESEQSA
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCC
PFYYVILPMLPLFFMLTFSSLGVKTINVGMATAIILSIFISLVFEFIREREVKPVFEKLQ
CEEEEHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GVFDDMGKVFASVVTLIIAGQTFSMGLKSIGAIDSMLHMASSVGLSAAVIILFMALLTFI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ISALMGSGNAAFFSFAPMVPQIAHKIGANTVDMILPIQLSAGFGRTISPIAGVIIAVAGI
HHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCC
SGLSPFDIVRRTLIPMVSGWLLMLILTFSKGGQLEQLMPFLIVILVLSVGVGWIMKRKNN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCC
RTQLTQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]