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The map label for this gene is aspC [H]

Identifier: 59712095

GI number: 59712095

Start: 1647001

End: 1648200

Strand: Direct

Name: aspC [H]

Synonym: VF_1488

Alternate gene names: 59712095

Gene position: 1647001-1648200 (Clockwise)

Preceding gene: 59712094

Following gene: 59712098

Centisome position: 56.84

GC content: 42.83

Gene sequence:

>1200_bases
ATGATGACTATGTTTGAAAAAATCGCTGCCGCTCCTGCTGACCCTATTCTTGGCTTAACAGATGAATTTAAAAATGACCC
TCGTGCTGAAAAAATCAACCTTGGTGTTGGTATTTACAAAAACGAAGCGGGTCAAACTCCAGTTTTAACCACAGTTAAAA
AAGCAGAAGCAGTATTGCTTGATACAGAAAAAACAAAGTCATACCTAACCATTCAAGGTACCGCAGAATACGGCCTTGCA
GTACAAAAGCTACTGTTTGGCGCTGATGCACAAGTAATCACTGAAAAACGTGCACAAACAGCTCAAGCTCCAGGTGGTAC
TGGTGCGCTACGTGTAGCTGGTGAATTCATCAAACGTCAACTTGGCGATGTAAAAATTTGGATCAGCAACCCTACATGGG
CAAACCACATTGGTGTATTTACTGCTGCTGGTATTGAAACAGCGCAATACACTTACTACAACGCAGAAACGAAATCTAAA
GACTTCGCTGCAATGCTAACGGATTTACAACAAGCGGAAGCTGGTGATGTGGTTCTTCTACACGGTTGTTGTCATAACCC
TACTGGTATCGATCCAACGGCTGATGAGTGGGAAGAGCTAGCTAAACTATGTGCAAATAAAGGTCTACTTCCACTGTTTG
ATTTCGCATACCAAGGTTTTGCAAAAGGTGTTGAAGAAGATGCGGCTGGTTTACGTACTTTTGCTCAATACTGCCCAGAG
CTGCTTGTAGCAAGTTCGTTCTCTAAGAACTTTGGTTTGTATAACGAGCGTGTTGGTGCATTTACTCTTGTTGCTAAAGA
CGCAACGGTTGCTGCGGATGCATTCTCTCAAGTTAAAGCTATCATCCGTTCTATCTACTCTAACCCACCAGCTCACGGTG
CTGCTGTTGTTACGCATATTCTTAATGACGATGCGCTACGTGCAGAATGGGAGCAAGAAGTCGCTGAAATGCGTGACCGT
ATTCAAGAGATGCGTACTTTGTTTGTTACCACACTAAAAGAGCAAGGTGTGGATGCAGACTTTAGCTTTATTGAACGTCA
AAACGGTATGTTCTCTTTCTCTGGTCTTTCTAAAGAGCAAGTAAATCGCCTGAAAGACGAATTCGCAATTTACATCGTTG
GTTCTGGCCGTATCAGTGTTGCTGGTATGACAAAAGACAACATGCTTCCTTTATGTAAAGGTATTGCTGCGGTTCTTTAA

Upstream 100 bases:

>100_bases
TAAATCCATTTAATTTGCTTTTTTCGTTACCTAACCGTTGCAAACTTACAGGATTAACAGGTATAAATAAGCTAACTCTT
TTATTTTACTTACACCATGG

Downstream 100 bases:

>100_bases
GAATCAGAAGTAATTGTAAGACATAGAAAAGGCGCTTTAATTAGCGCCTTTTTTTATGCCAGTTTCACACTTTCTTAGCC
TGAATGACAATGTTCCTTGG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MMTMFEKIAAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLTTVKKAEAVLLDTEKTKSYLTIQGTAEYGLA
VQKLLFGADAQVITEKRAQTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHIGVFTAAGIETAQYTYYNAETKSK
DFAAMLTDLQQAEAGDVVLLHGCCHNPTGIDPTADEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDAAGLRTFAQYCPE
LLVASSFSKNFGLYNERVGAFTLVAKDATVAADAFSQVKAIIRSIYSNPPAHGAAVVTHILNDDALRAEWEQEVAEMRDR
IQEMRTLFVTTLKEQGVDADFSFIERQNGMFSFSGLSKEQVNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL

Sequences:

>Translated_399_residues
MMTMFEKIAAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLTTVKKAEAVLLDTEKTKSYLTIQGTAEYGLA
VQKLLFGADAQVITEKRAQTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHIGVFTAAGIETAQYTYYNAETKSK
DFAAMLTDLQQAEAGDVVLLHGCCHNPTGIDPTADEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDAAGLRTFAQYCPE
LLVASSFSKNFGLYNERVGAFTLVAKDATVAADAFSQVKAIIRSIYSNPPAHGAAVVTHILNDDALRAEWEQEVAEMRDR
IQEMRTLFVTTLKEQGVDADFSFIERQNGMFSFSGLSKEQVNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL
>Mature_399_residues
MMTMFEKIAAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLTTVKKAEAVLLDTEKTKSYLTIQGTAEYGLA
VQKLLFGADAQVITEKRAQTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHIGVFTAAGIETAQYTYYNAETKSK
DFAAMLTDLQQAEAGDVVLLHGCCHNPTGIDPTADEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDAAGLRTFAQYCPE
LLVASSFSKNFGLYNERVGAFTLVAKDATVAADAFSQVKAIIRSIYSNPPAHGAAVVTHILNDDALRAEWEQEVAEMRDR
IQEMRTLFVTTLKEQGVDADFSFIERQNGMFSFSGLSKEQVNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=42.9292929292929, Blast_Score=330, Evalue=1e-90,
Organism=Homo sapiens, GI4504067, Length=394, Percent_Identity=40.6091370558376, Blast_Score=305, Evalue=5e-83,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=27.4151436031332, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=63.6363636363636, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=44.080604534005, Blast_Score=359, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71981858, Length=399, Percent_Identity=42.1052631578947, Blast_Score=347, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI25147133, Length=397, Percent_Identity=40.8060453400504, Blast_Score=325, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17569539, Length=397, Percent_Identity=37.7833753148615, Blast_Score=288, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI17569537, Length=389, Percent_Identity=29.8200514138817, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=35.361216730038, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=37.5586854460094, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323055, Length=407, Percent_Identity=37.5921375921376, Blast_Score=295, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6322743, Length=430, Percent_Identity=31.3953488372093, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=40.9547738693467, Blast_Score=327, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=40.9547738693467, Blast_Score=327, Evalue=8e-90,
Organism=Drosophila melanogaster, GI19922362, Length=401, Percent_Identity=42.3940149625935, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24654046, Length=401, Percent_Identity=42.3940149625935, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=41.3881748071979, Blast_Score=323, Evalue=1e-88,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43403; Mature: 43403

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTMFEKIAAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLTTVKKAEAVLL
CCHHHHHHHCCCCCCCCCCCHHHCCCCCCEEEEECEEEEECCCCCCCHHHHHHHHCEEEE
DTEKTKSYLTIQGTAEYGLAVQKLLFGADAQVITEKRAQTAQAPGGTGALRVAGEFIKRQ
ECCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LGDVKIWISNPTWANHIGVFTAAGIETAQYTYYNAETKSKDFAAMLTDLQQAEAGDVVLL
HCCEEEEECCCCCCHHCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
HGCCHNPTGIDPTADEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDAAGLRTFAQYCPE
ECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLVASSFSKNFGLYNERVGAFTLVAKDATVAADAFSQVKAIIRSIYSNPPAHGAAVVTHI
HHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LNDDALRAEWEQEVAEMRDRIQEMRTLFVTTLKEQGVDADFSFIERQNGMFSFSGLSKEQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCCHHH
VNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL
HHHHHHCEEEEEEECCEEEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MMTMFEKIAAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLTTVKKAEAVLL
CCHHHHHHHCCCCCCCCCCCHHHCCCCCCEEEEECEEEEECCCCCCCHHHHHHHHCEEEE
DTEKTKSYLTIQGTAEYGLAVQKLLFGADAQVITEKRAQTAQAPGGTGALRVAGEFIKRQ
ECCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LGDVKIWISNPTWANHIGVFTAAGIETAQYTYYNAETKSKDFAAMLTDLQQAEAGDVVLL
HCCEEEEECCCCCCHHCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
HGCCHNPTGIDPTADEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDAAGLRTFAQYCPE
ECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLVASSFSKNFGLYNERVGAFTLVAKDATVAADAFSQVKAIIRSIYSNPPAHGAAVVTHI
HHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LNDDALRAEWEQEVAEMRDRIQEMRTLFVTTLKEQGVDADFSFIERQNGMFSFSGLSKEQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCCHHH
VNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL
HHHHHHCEEEEEEECCEEEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]