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The map label for this gene is hipB [H]

Identifier: 59712076

GI number: 59712076

Start: 1627697

End: 1627960

Strand: Direct

Name: hipB [H]

Synonym: VF_1469

Alternate gene names: 59712076

Gene position: 1627697-1627960 (Clockwise)

Preceding gene: 59712074

Following gene: 59712077

Centisome position: 56.18

GC content: 37.88

Gene sequence:

>264_bases
ATGATGGGGTGTATGATGATTTATAATCCAAAGCAATTAGCTAACCACTTAAAGCTTATTAGAACCAAACACAATTTGAC
TCAAACAGAGCTTGCTAAAAAAGTTGGTGTAAAACAATCCACCCTATCTAGCTTTGAGAATCATCCTGAAACGACTCAGT
TACAGACACTCTTTAAGATCCTTCATGCATTAGAAGTTCATTGCATTATTCAAGAGCAAGTCCCAGCAAGTCACGAAGAC
AATCTAGACGATGAGGCGTGGTAA

Upstream 100 bases:

>100_bases
AGCGCACAAACCAACTTTATCCTCGATCGGGGATATACATTGACTTATCCCCGATAGGGGATATATTATTAATTATCCTC
TACCGGGGATATCACATAAT

Downstream 100 bases:

>100_bases
TGGCTATATTAATTGCATACATGAATGGTGAGCGCGTTGGAGAATTTACTAAACTCAGTAACGGTGCACACCAGTTTCAA
TACGATAAATCATGGATTGA

Product: DNA-binding transcriptional regulator HipB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 87

Protein sequence:

>87_residues
MMGCMMIYNPKQLANHLKLIRTKHNLTQTELAKKVGVKQSTLSSFENHPETTQLQTLFKILHALEVHCIIQEQVPASHED
NLDDEAW

Sequences:

>Translated_87_residues
MMGCMMIYNPKQLANHLKLIRTKHNLTQTELAKKVGVKQSTLSSFENHPETTQLQTLFKILHALEVHCIIQEQVPASHED
NLDDEAW
>Mature_87_residues
MMGCMMIYNPKQLANHLKLIRTKHNLTQTELAKKVGVKQSTLSSFENHPETTQLQTLFKILHALEVHCIIQEQVPASHED
NLDDEAW

Specific function: Binds to operator sites with the consensus sequence 5-'TATCCN(8)GGATA-3' and repress the hip operon promoter [H]

COG id: COG1396

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787786, Length=82, Percent_Identity=50, Blast_Score=86, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982 [H]

Pfam domain/function: PF01381 HTH_3 [H]

EC number: NA

Molecular weight: Translated: 10010; Mature: 10010

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGCMMIYNPKQLANHLKLIRTKHNLTQTELAKKVGVKQSTLSSFENHPETTQLQTLFKI
CCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHH
LHALEVHCIIQEQVPASHEDNLDDEAW
HHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMGCMMIYNPKQLANHLKLIRTKHNLTQTELAKKVGVKQSTLSSFENHPETTQLQTLFKI
CCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHH
LHALEVHCIIQEQVPASHEDNLDDEAW
HHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1715862; 9097039; 9278503; 8021189 [H]