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The map label for this gene is cph2 [H]

Identifier: 59711957

GI number: 59711957

Start: 1493478

End: 1495523

Strand: Direct

Name: cph2 [H]

Synonym: VF_1350

Alternate gene names: 59711957

Gene position: 1493478-1495523 (Clockwise)

Preceding gene: 59711948

Following gene: 59711973

Centisome position: 51.54

GC content: 33.77

Gene sequence:

>2046_bases
ATGAACCTTAGGCTTTTAACAGCTTCGCTGATTTCTCTTATTTTAATTATTATTCTTTCTATTACCTTTTTATCTGAAGA
TGTATCTGTACATTCAACTAAAGAATCACCTTCAATTAAAAAAGCCATTGAATTAATCCTTAACATTCAATCAGCCCGAC
GTGGTGAACACCTAGATTATTTAGAGTCTGTTGTCTCTCAACACGCCAGGTTAAAAGCAAACAAATCAGAAACCTTCTAT
ATAGAATTTCTTAAAGGTTATATCGCCTCTGCAAACAATCAGTTTGATTTGGCTGAAAAGCATTTTAATCATGCTCAACA
ATACATCTACCCTGCACTTCCTTCGCATGTATTGTCTCGTTTTTATTATGAAAGAAGTTATATTGAAATAGAGCAAGATC
AATACGAAAGATCGAAACTTAGCTACCAAAATGCAGAAAATTTATTTAATTCAAATCAAGACTATAGTCGTGCTTTCATT
TCGATCTCATTAGGTCGAACGTATGATCTTGCACACGTAGAACAAGGCAGTTTACTCAGCATTCAGCAAGCCCAAAAAAC
GCTCGAATTTGCACAAAAAATCAAATTTCCAGAAATGGAGAACGTTTATTTCATCCTTGGCCTTTCCTACTGGAACAATA
ACCAAACCATTCTAGGCATTGATTTTAAATTAAAAGCGTTAAATATTTACATAGAGAAGAAACAGTATAGCGATATCGTT
TACACCTTAACGGATATTGGTATCGATTATCTGTTTTTAAAAAACTATGACGAAGCGATTCGCCAATTAACGCAAGCACT
TGAATATCAGAATAAAAATAACAACACAGAACCAGACGAAGCCTATTACATCGTATACAAACTATATAGTGCTTATCTTC
AAATCAACGACATGGAAAATGCAAAGTATTATTTAGATGAAGCTGCGAGACTCCTAAGAATACAGAAAGACTCCATTGTT
AAAGAGAATTTTCAAACAAACCAATTATTGCTAGAAGCTGAATACCTGTCGATTACAGGAAAAGCGAAAGAAGCACTCAT
GCTGCTAACTCAAGCTAATGAGCGCCATAAGAATGGACTTTCAAACAGCTTTTATCATTTTGATGTCACCTTATATAACA
CCTATGGCAAGGTATACAATCACTTAGGTTTATATGATGACTCTATCTATCACCACACTTTAGCAAAAAAAGAAATTCAA
CAACGTAAACTCTTTTATCTAGAAGATGAAACGTATTTCTACTTATATGATGCTTATCAAAAACAAAAAGACTATCAAAA
AGCGGCTTTGTATTTAGCAAAAAGCCACGCAGTAAAAACCAAACAGTTGAATGATAATAACCAAGCACAAACGCAGTTTT
TACTTCACTCTTTTGATAATAAAAAGAAAGAAAATAGAATTTTACAACTTGAAAGAAACGCCAGTAAGATCATGTTCTTC
TCTGGTTTCCTTCTTTGTATTTTGATCGTTATTGCCGCTTTCGCTCGAATTTTGATGAATAAAAACAAAGAGATCAACGC
ACTTAATCTTAAATTACATGATCTTAGTTTAACGGACGGTTTAACAGCAGTACCCAACCGCAGAGCATTAGAACTTCATC
TATTAGAGAATAAGCAAGATTTAACGGTTCGCTCTGTCATGATGATAGACATTGATTACTTTAAAAAATACAACGACACC
TATGGTCATAAAAAAGGTGATGAAGCATTAATCGCCGTCGCTAAGGCATTAAAAGAAAGCTGTAAAGAAAATGACTTCCT
TACAAGATTTGGTGGTGAAGAATTTATTATTGTGATGAAAAATACCAATAAAGCAGAATCAATACAGATGGCCGAAAAAA
TTCAAGCCTGTATTACTTCTCTATGTATTCCTCACGAGAGTTCTGATGTCTCTTCCTTTATTACGTTGAGTATTGGTATT
ACTACCTACTCTGTTAATAAAGACGATAAAGCAAACAATGAAAAGGCGATCATCGAAGCTGATAAGGCGCTGTACTATTC
TAAAAATAAGGGCAGAAACCAGAGCAATCACTTTTATGATATTTAA

Upstream 100 bases:

>100_bases
TAACAGCAAAAATACTCTCTCAATAATAAGATCTGAGTGTATATTTATACTAATTCTATTGATAAAATAAATAATACTGA
TTTGTTTTTGATATTCCTGC

Downstream 100 bases:

>100_bases
ATATAATGTTTAAAGCCTGTAATTATACAGGCTTTAAATCGTGCATTATTTAGCAGGAGCAAAGTCTTCTGCAGCTTGAC
GGTGCGCCGTGTAAATTGCC

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MNLRLLTASLISLILIIILSITFLSEDVSVHSTKESPSIKKAIELILNIQSARRGEHLDYLESVVSQHARLKANKSETFY
IEFLKGYIASANNQFDLAEKHFNHAQQYIYPALPSHVLSRFYYERSYIEIEQDQYERSKLSYQNAENLFNSNQDYSRAFI
SISLGRTYDLAHVEQGSLLSIQQAQKTLEFAQKIKFPEMENVYFILGLSYWNNNQTILGIDFKLKALNIYIEKKQYSDIV
YTLTDIGIDYLFLKNYDEAIRQLTQALEYQNKNNNTEPDEAYYIVYKLYSAYLQINDMENAKYYLDEAARLLRIQKDSIV
KENFQTNQLLLEAEYLSITGKAKEALMLLTQANERHKNGLSNSFYHFDVTLYNTYGKVYNHLGLYDDSIYHHTLAKKEIQ
QRKLFYLEDETYFYLYDAYQKQKDYQKAALYLAKSHAVKTKQLNDNNQAQTQFLLHSFDNKKKENRILQLERNASKIMFF
SGFLLCILIVIAAFARILMNKNKEINALNLKLHDLSLTDGLTAVPNRRALELHLLENKQDLTVRSVMMIDIDYFKKYNDT
YGHKKGDEALIAVAKALKESCKENDFLTRFGGEEFIIVMKNTNKAESIQMAEKIQACITSLCIPHESSDVSSFITLSIGI
TTYSVNKDDKANNEKAIIEADKALYYSKNKGRNQSNHFYDI

Sequences:

>Translated_681_residues
MNLRLLTASLISLILIIILSITFLSEDVSVHSTKESPSIKKAIELILNIQSARRGEHLDYLESVVSQHARLKANKSETFY
IEFLKGYIASANNQFDLAEKHFNHAQQYIYPALPSHVLSRFYYERSYIEIEQDQYERSKLSYQNAENLFNSNQDYSRAFI
SISLGRTYDLAHVEQGSLLSIQQAQKTLEFAQKIKFPEMENVYFILGLSYWNNNQTILGIDFKLKALNIYIEKKQYSDIV
YTLTDIGIDYLFLKNYDEAIRQLTQALEYQNKNNNTEPDEAYYIVYKLYSAYLQINDMENAKYYLDEAARLLRIQKDSIV
KENFQTNQLLLEAEYLSITGKAKEALMLLTQANERHKNGLSNSFYHFDVTLYNTYGKVYNHLGLYDDSIYHHTLAKKEIQ
QRKLFYLEDETYFYLYDAYQKQKDYQKAALYLAKSHAVKTKQLNDNNQAQTQFLLHSFDNKKKENRILQLERNASKIMFF
SGFLLCILIVIAAFARILMNKNKEINALNLKLHDLSLTDGLTAVPNRRALELHLLENKQDLTVRSVMMIDIDYFKKYNDT
YGHKKGDEALIAVAKALKESCKENDFLTRFGGEEFIIVMKNTNKAESIQMAEKIQACITSLCIPHESSDVSSFITLSIGI
TTYSVNKDDKANNEKAIIEADKALYYSKNKGRNQSNHFYDI
>Mature_681_residues
MNLRLLTASLISLILIIILSITFLSEDVSVHSTKESPSIKKAIELILNIQSARRGEHLDYLESVVSQHARLKANKSETFY
IEFLKGYIASANNQFDLAEKHFNHAQQYIYPALPSHVLSRFYYERSYIEIEQDQYERSKLSYQNAENLFNSNQDYSRAFI
SISLGRTYDLAHVEQGSLLSIQQAQKTLEFAQKIKFPEMENVYFILGLSYWNNNQTILGIDFKLKALNIYIEKKQYSDIV
YTLTDIGIDYLFLKNYDEAIRQLTQALEYQNKNNNTEPDEAYYIVYKLYSAYLQINDMENAKYYLDEAARLLRIQKDSIV
KENFQTNQLLLEAEYLSITGKAKEALMLLTQANERHKNGLSNSFYHFDVTLYNTYGKVYNHLGLYDDSIYHHTLAKKEIQ
QRKLFYLEDETYFYLYDAYQKQKDYQKAALYLAKSHAVKTKQLNDNNQAQTQFLLHSFDNKKKENRILQLERNASKIMFF
SGFLLCILIVIAAFARILMNKNKEINALNLKLHDLSLTDGLTAVPNRRALELHLLENKQDLTVRSVMMIDIDYFKKYNDT
YGHKKGDEALIAVAKALKESCKENDFLTRFGGEEFIIVMKNTNKAESIQMAEKIQACITSLCIPHESSDVSSFITLSIGI
TTYSVNKDDKANNEKAIIEADKALYYSKNKGRNQSNHFYDI

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=32.9411764705882, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693134, Length=167, Percent_Identity=34.1317365269461, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI87081881, Length=161, Percent_Identity=34.7826086956522, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787802, Length=197, Percent_Identity=32.994923857868, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787541, Length=168, Percent_Identity=34.5238095238095, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787262, Length=158, Percent_Identity=32.9113924050633, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=34.1463414634146, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=31.3253012048193, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081974, Length=203, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=132, Percent_Identity=29.5454545454545, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081977, Length=162, Percent_Identity=32.0987654320988, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 79124; Mature: 79124

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRLLTASLISLILIIILSITFLSEDVSVHSTKESPSIKKAIELILNIQSARRGEHLDY
CCEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHH
LESVVSQHARLKANKSETFYIEFLKGYIASANNQFDLAEKHFNHAQQYIYPALPSHVLSR
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
FYYERSYIEIEQDQYERSKLSYQNAENLFNSNQDYSRAFISISLGRTYDLAHVEQGSLLS
HHHHCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCEEEEEECCCCCEEE
IQQAQKTLEFAQKIKFPEMENVYFILGLSYWNNNQTILGIDFKLKALNIYIEKKQYSDIV
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCEEEEEEEEEEEEEEEEECCCCCCCE
YTLTDIGIDYLFLKNYDEAIRQLTQALEYQNKNNNTEPDEAYYIVYKLYSAYLQINDMEN
EEHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEECCCC
AKYYLDEAARLLRIQKDSIVKENFQTNQLLLEAEYLSITGKAKEALMLLTQANERHKNGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCHHHHHHHHHHCCHHHHCCC
SNSFYHFDVTLYNTYGKVYNHLGLYDDSIYHHTLAKKEIQQRKLFYLEDETYFYLYDAYQ
CCCEEEEEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEEEECHH
KQKDYQKAALYLAKSHAVKTKQLNDNNQAQTQFLLHSFDNKKKENRILQLERNASKIMFF
HHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEHH
SGFLLCILIVIAAFARILMNKNKEINALNLKLHDLSLTDGLTAVPNRRALELHLLENKQD
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCC
LTVRSVMMIDIDYFKKYNDTYGHKKGDEALIAVAKALKESCKENDFLTRFGGEEFIIVMK
CEEEEEEEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEE
NTNKAESIQMAEKIQACITSLCIPHESSDVSSFITLSIGITTYSVNKDDKANNEKAIIEA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCCCEEEEE
DKALYYSKNKGRNQSNHFYDI
CHHEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNLRLLTASLISLILIIILSITFLSEDVSVHSTKESPSIKKAIELILNIQSARRGEHLDY
CCEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHH
LESVVSQHARLKANKSETFYIEFLKGYIASANNQFDLAEKHFNHAQQYIYPALPSHVLSR
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
FYYERSYIEIEQDQYERSKLSYQNAENLFNSNQDYSRAFISISLGRTYDLAHVEQGSLLS
HHHHCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCEEEEEECCCCCEEE
IQQAQKTLEFAQKIKFPEMENVYFILGLSYWNNNQTILGIDFKLKALNIYIEKKQYSDIV
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCEEEEEEEEEEEEEEEEECCCCCCCE
YTLTDIGIDYLFLKNYDEAIRQLTQALEYQNKNNNTEPDEAYYIVYKLYSAYLQINDMEN
EEHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEECCCC
AKYYLDEAARLLRIQKDSIVKENFQTNQLLLEAEYLSITGKAKEALMLLTQANERHKNGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCHHHHHHHHHHCCHHHHCCC
SNSFYHFDVTLYNTYGKVYNHLGLYDDSIYHHTLAKKEIQQRKLFYLEDETYFYLYDAYQ
CCCEEEEEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEEEECHH
KQKDYQKAALYLAKSHAVKTKQLNDNNQAQTQFLLHSFDNKKKENRILQLERNASKIMFF
HHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEHH
SGFLLCILIVIAAFARILMNKNKEINALNLKLHDLSLTDGLTAVPNRRALELHLLENKQD
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCC
LTVRSVMMIDIDYFKKYNDTYGHKKGDEALIAVAKALKESCKENDFLTRFGGEEFIIVMK
CEEEEEEEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEE
NTNKAESIQMAEKIQACITSLCIPHESSDVSSFITLSIGITTYSVNKDDKANNEKAIIEA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCCCEEEEE
DKALYYSKNKGRNQSNHFYDI
CHHEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]