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The map label for this gene is luxQ [H]

Identifier: 59711903

GI number: 59711903

Start: 1446707

End: 1448785

Strand: Reverse

Name: luxQ [H]

Synonym: VF_1296

Alternate gene names: 59711903

Gene position: 1448785-1446707 (Counterclockwise)

Preceding gene: 59711904

Following gene: 59711902

Centisome position: 50.0

GC content: 33.48

Gene sequence:

>2079_bases
GTGAAAAATCATTCTGAAAAAGAACAATTTCAAGAGATACTGTTGGAATTAAAGCGAAGTAAAGAACGTGAAGCCCAACT
TCATAAAGAAAACCAAGTTATTTTGCGAGGGGTATCTGCAATTTCAGATGCTCAAACAAAAGAAGATATTTTTAATGGTT
TATTAAATGTCATTAAGGAATTTGTCGAATTCGATAATGCTATTGTGGTTTCATCTACAGATAAAGACAGTTTCTCTGTA
TTAGCATCAACAAATCCGTATTTCGATCATTTAACATGGCGTTATAACGATCTTTTTCATCGAGCCTGTCATGATGAAAC
TATCATCTTATTTCAACCGCATAAAACAAATGAATTTCTATTCAAAAATACAGAATTACAGAGCTTATTTTCTTCTGTAG
CAATATGTGGTTTAAAGTCTCATTCTGGCTATGCTGTTATTATTTTAGCATGTTCTAAGTTTGGGGCTTATTCAACTCTC
GAGAAAGAGAAAATAGAACGCTTTATGCCATTAGTTGAGCGAGCAGTAATTGATATTGATTATAAAGAACGCCTCAATGC
GATGGTTTCACTGAAGACAAAAGAACTTTTTCTAAGTAAAGAGCGATTTCAAGACTTTGCTGAAACCGTTGGTGACTGGT
TTTGGGAAACGGATCCTCAATTTAATTTTACCTACTTGTCTGATACCAAAATAAATAACACATCAATCATCTCTCAAAAT
CTACTTAGCTTGATCAGTAATGATTTCATTAATTCTACGATAATTGAATCAGAGAAGAGGCTTGTGCCATTTCACGAAGT
TGAATGGAACCCTGATATTTTCAATAATAAAGTTTGGTTAAGCCTGAGTGGTAAACCATTTTTTGATGAGTTTGGTACTT
TTGTTGGTTACCGAGGTACGGCCAAAGATATTTCAGCGAGAAAAAAACGAATCAGAGATATTCAAACCGCTAAAACTGAA
GCTGAAAAAGCCAATAAAGCAAAATCACAATTTTTAGCTATGATGAGCCATGAAATTAGAACACCATTAAACTCAATACT
TGGTCTTGTTGATGTGTTTCATAGTAGCTTGCTTTCTGAAGAACAATTAGATTGGTTAAATCAAATGGAAAGTTCCTCTC
AATTGCTGCTTACAATAATCAGTGATGTACTTGATATATCTAGGATTGAAGCGGGAACATTTGTTTTAAATGAACAACCA
ATTGATTTATTAAGATCTTTAAATACATCTATTAATTTTCTAGATACAAGAGCTAAAGATAAAGGAATAACTTTAACTGT
TACGGCGTCACAAAATGTACCTAAATATGTTTTTGCTGATGCAACCAGGTTATCCCAAGTAATCTTCAATTTAGTTGGTA
ATGCAATTAAATTCACTAATCATGGACATGTCGCTGTTAAGATCGAGAAGCTACCTAATAATTCAATATCCATATCAGTT
AGTGATACCGGTATCGGCATTGCTTCAACAACATTAGAGCAATTGTTTAAACCATTTGTGCAAGCAGACAGTTCAATAAC
TAGAAAATACGGTGGAACTGGTCTTGGTTTAGCCATTATTAAGCGCTTAGTTGAATTAATGCAAGGAACGATAACAGTAG
AGAGCCGATTAAATATAGGCAGTACTTTTAAAATAACTCTGCCTTTAAAAGAAATCAGCGATTTACCGAAACAATTAAAT
AATGAAGCTAAAGAATTGGTTAATCAGCGTAGCTTAAATATCTTGTTAGCAGAAGATAATAAAGCAAATCAGGCGGTTCT
TCAGATATTGCTAGAAAAACAAGGTCACCATGTATCAATAGTCAGTAATGGTGAAGAGGCCATTTCAATATTTAAACATC
AGACAAACGGTTGTTTTTTTGATGTGGTTCTTATGGATGTATCGATGCCAGTTAAAGATGGCATCAGTGCAACAACTGAA
TTAAGAAAGTTAGGTATAGAGCTGCCTATAATAGCAATCACAGCTCATGCAATGGAGACAGAAAAAGAAATGTGTTTGGA
AGCTGGTATGAACGATTTCATATCAAAACCAATCAGAGCAAAAGACTTATCAGATATTTTAATCAAATACAGTTGTTAA

Upstream 100 bases:

>100_bases
CCCATTTACGTTTGGTGAACAAGGTCGTTTTACTGGTGGGGAAAATGCTCACGGTAACTTAATGGTATCAACCGTTTTAT
TTCATAATTAGGTATTGTCT

Downstream 100 bases:

>100_bases
GTAACTTAGCTTGTAAGAATGAGGCTAATAATCAATAGATAAATACGAAGTATTATTTAATGATTATTAGCTATTTTATG
GTAAATACGATTATGGTTAA

Product: hybrid sensory histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MKNHSEKEQFQEILLELKRSKEREAQLHKENQVILRGVSAISDAQTKEDIFNGLLNVIKEFVEFDNAIVVSSTDKDSFSV
LASTNPYFDHLTWRYNDLFHRACHDETIILFQPHKTNEFLFKNTELQSLFSSVAICGLKSHSGYAVIILACSKFGAYSTL
EKEKIERFMPLVERAVIDIDYKERLNAMVSLKTKELFLSKERFQDFAETVGDWFWETDPQFNFTYLSDTKINNTSIISQN
LLSLISNDFINSTIIESEKRLVPFHEVEWNPDIFNNKVWLSLSGKPFFDEFGTFVGYRGTAKDISARKKRIRDIQTAKTE
AEKANKAKSQFLAMMSHEIRTPLNSILGLVDVFHSSLLSEEQLDWLNQMESSSQLLLTIISDVLDISRIEAGTFVLNEQP
IDLLRSLNTSINFLDTRAKDKGITLTVTASQNVPKYVFADATRLSQVIFNLVGNAIKFTNHGHVAVKIEKLPNNSISISV
SDTGIGIASTTLEQLFKPFVQADSSITRKYGGTGLGLAIIKRLVELMQGTITVESRLNIGSTFKITLPLKEISDLPKQLN
NEAKELVNQRSLNILLAEDNKANQAVLQILLEKQGHHVSIVSNGEEAISIFKHQTNGCFFDVVLMDVSMPVKDGISATTE
LRKLGIELPIIAITAHAMETEKEMCLEAGMNDFISKPIRAKDLSDILIKYSC

Sequences:

>Translated_692_residues
MKNHSEKEQFQEILLELKRSKEREAQLHKENQVILRGVSAISDAQTKEDIFNGLLNVIKEFVEFDNAIVVSSTDKDSFSV
LASTNPYFDHLTWRYNDLFHRACHDETIILFQPHKTNEFLFKNTELQSLFSSVAICGLKSHSGYAVIILACSKFGAYSTL
EKEKIERFMPLVERAVIDIDYKERLNAMVSLKTKELFLSKERFQDFAETVGDWFWETDPQFNFTYLSDTKINNTSIISQN
LLSLISNDFINSTIIESEKRLVPFHEVEWNPDIFNNKVWLSLSGKPFFDEFGTFVGYRGTAKDISARKKRIRDIQTAKTE
AEKANKAKSQFLAMMSHEIRTPLNSILGLVDVFHSSLLSEEQLDWLNQMESSSQLLLTIISDVLDISRIEAGTFVLNEQP
IDLLRSLNTSINFLDTRAKDKGITLTVTASQNVPKYVFADATRLSQVIFNLVGNAIKFTNHGHVAVKIEKLPNNSISISV
SDTGIGIASTTLEQLFKPFVQADSSITRKYGGTGLGLAIIKRLVELMQGTITVESRLNIGSTFKITLPLKEISDLPKQLN
NEAKELVNQRSLNILLAEDNKANQAVLQILLEKQGHHVSIVSNGEEAISIFKHQTNGCFFDVVLMDVSMPVKDGISATTE
LRKLGIELPIIAITAHAMETEKEMCLEAGMNDFISKPIRAKDLSDILIKYSC
>Mature_692_residues
MKNHSEKEQFQEILLELKRSKEREAQLHKENQVILRGVSAISDAQTKEDIFNGLLNVIKEFVEFDNAIVVSSTDKDSFSV
LASTNPYFDHLTWRYNDLFHRACHDETIILFQPHKTNEFLFKNTELQSLFSSVAICGLKSHSGYAVIILACSKFGAYSTL
EKEKIERFMPLVERAVIDIDYKERLNAMVSLKTKELFLSKERFQDFAETVGDWFWETDPQFNFTYLSDTKINNTSIISQN
LLSLISNDFINSTIIESEKRLVPFHEVEWNPDIFNNKVWLSLSGKPFFDEFGTFVGYRGTAKDISARKKRIRDIQTAKTE
AEKANKAKSQFLAMMSHEIRTPLNSILGLVDVFHSSLLSEEQLDWLNQMESSSQLLLTIISDVLDISRIEAGTFVLNEQP
IDLLRSLNTSINFLDTRAKDKGITLTVTASQNVPKYVFADATRLSQVIFNLVGNAIKFTNHGHVAVKIEKLPNNSISISV
SDTGIGIASTTLEQLFKPFVQADSSITRKYGGTGLGLAIIKRLVELMQGTITVESRLNIGSTFKITLPLKEISDLPKQLN
NEAKELVNQRSLNILLAEDNKANQAVLQILLEKQGHHVSIVSNGEEAISIFKHQTNGCFFDVVLMDVSMPVKDGISATTE
LRKLGIELPIIAITAHAMETEKEMCLEAGMNDFISKPIRAKDLSDILIKYSC

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=424, Percent_Identity=32.311320754717, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1788713, Length=406, Percent_Identity=33.743842364532, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI87081816, Length=397, Percent_Identity=32.2418136020151, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=45.531914893617, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=37.9032258064516, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786600, Length=250, Percent_Identity=29.6, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=24.6913580246914, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=29.3617021276596, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=27.8026905829596, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=25.5230125523013, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=29.1479820627803, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=24.7232472324723, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788279, Length=228, Percent_Identity=27.6315789473684, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=28.3842794759825, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=214, Percent_Identity=28.0373831775701, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=115, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=95, Percent_Identity=48.4210526315789, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322000, Length=154, Percent_Identity=35.0649350649351, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78028; Mature: 78028

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHSEKEQFQEILLELKRSKEREAQLHKENQVILRGVSAISDAQTKEDIFNGLLNVIKE
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVEFDNAIVVSSTDKDSFSVLASTNPYFDHLTWRYNDLFHRACHDETIILFQPHKTNEFL
HHHCCCEEEEECCCCCCEEEEECCCCCHHCCEEHHHHHHHHHCCCCEEEEECCCCCCCCE
FKNTELQSLFSSVAICGLKSHSGYAVIILACSKFGAYSTLEKEKIERFMPLVERAVIDID
EECCHHHHHHHHHHHHCEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
YKERLNAMVSLKTKELFLSKERFQDFAETVGDWFWETDPQFNFTYLSDTKINNTSIISQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
LLSLISNDFINSTIIESEKRLVPFHEVEWNPDIFNNKVWLSLSGKPFFDEFGTFVGYRGT
HHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCC
AKDISARKKRIRDIQTAKTEAEKANKAKSQFLAMMSHEIRTPLNSILGLVDVFHSSLLSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCH
EQLDWLNQMESSSQLLLTIISDVLDISRIEAGTFVLNEQPIDLLRSLNTSINFLDTRAKD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCEEEECCCCC
KGITLTVTASQNVPKYVFADATRLSQVIFNLVGNAIKFTNHGHVAVKIEKLPNNSISISV
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEECCCCCEEEEE
SDTGIGIASTTLEQLFKPFVQADSSITRKYGGTGLGLAIIKRLVELMQGTITVESRLNIG
ECCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCC
STFKITLPLKEISDLPKQLNNEAKELVNQRSLNILLAEDNKANQAVLQILLEKQGHHVSI
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCEEEE
VSNGEEAISIFKHQTNGCFFDVVLMDVSMPVKDGISATTELRKLGIELPIIAITAHAMET
EECCHHHHHHHHCCCCCEEEEEEEECCCCCHHCCCHHHHHHHHCCCCCCEEEEEHHHHHH
EKEMCLEAGMNDFISKPIRAKDLSDILIKYSC
HHHHHHHHCCHHHHCCCCCCCCHHHHHEEECC
>Mature Secondary Structure
MKNHSEKEQFQEILLELKRSKEREAQLHKENQVILRGVSAISDAQTKEDIFNGLLNVIKE
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVEFDNAIVVSSTDKDSFSVLASTNPYFDHLTWRYNDLFHRACHDETIILFQPHKTNEFL
HHHCCCEEEEECCCCCCEEEEECCCCCHHCCEEHHHHHHHHHCCCCEEEEECCCCCCCCE
FKNTELQSLFSSVAICGLKSHSGYAVIILACSKFGAYSTLEKEKIERFMPLVERAVIDID
EECCHHHHHHHHHHHHCEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
YKERLNAMVSLKTKELFLSKERFQDFAETVGDWFWETDPQFNFTYLSDTKINNTSIISQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
LLSLISNDFINSTIIESEKRLVPFHEVEWNPDIFNNKVWLSLSGKPFFDEFGTFVGYRGT
HHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCC
AKDISARKKRIRDIQTAKTEAEKANKAKSQFLAMMSHEIRTPLNSILGLVDVFHSSLLSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCH
EQLDWLNQMESSSQLLLTIISDVLDISRIEAGTFVLNEQPIDLLRSLNTSINFLDTRAKD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCEEEECCCCC
KGITLTVTASQNVPKYVFADATRLSQVIFNLVGNAIKFTNHGHVAVKIEKLPNNSISISV
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEECCCCCEEEEE
SDTGIGIASTTLEQLFKPFVQADSSITRKYGGTGLGLAIIKRLVELMQGTITVESRLNIG
ECCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCC
STFKITLPLKEISDLPKQLNNEAKELVNQRSLNILLAEDNKANQAVLQILLEKQGHHVSI
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCEEEE
VSNGEEAISIFKHQTNGCFFDVVLMDVSMPVKDGISATTELRKLGIELPIIAITAHAMET
EECCHHHHHHHHCCCCCEEEEEEEECCCCCHHCCCHHHHHHHHCCCCCCEEEEEHHHHHH
EKEMCLEAGMNDFISKPIRAKDLSDILIKYSC
HHHHHHHHCCHHHHCCCCCCCCHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA