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The map label for this gene is yeeO [H]

Identifier: 59711873

GI number: 59711873

Start: 1406883

End: 1408226

Strand: Reverse

Name: yeeO [H]

Synonym: VF_1266

Alternate gene names: 59711873

Gene position: 1408226-1406883 (Counterclockwise)

Preceding gene: 59711876

Following gene: 59711866

Centisome position: 48.6

GC content: 39.66

Gene sequence:

>1344_bases
ATGCTTGATAAAAGCAATCCTATTGAACGCCGAATGCAGATCACGACATTAGCGTGGCCGATTCTGGTGGAAATTTTACT
GCGTACAGCCATTAGTACCAGTGATGTATTCATGCTTAGTGGCTACTCTGATCTGGCAGTATCTGCTATTGGGGTCATCT
CGCAAATCATTTTCTTTTTAATGATAATTTCGATGATGGTGAGTACTGGTACTGGCATTCTTATTGGTCAATACAATGGA
TCTGGACGAACTCAACAATCAACCGATGTTGCGGTAGCCAGTGTTGTGCTTGGTGGAATATTAGGACTTGGCCTCAGTTT
ATTTGCCTTTTTTGCCGCAAATCCTATTGTCATCATGTATGGACTAGAAAGTGACGTTGCAACTTTTGCATACGATTATT
TAATTATTACAGGTTCTTTCACATTAACCGTAACCCTTGGTATCGTCTTCTCTACCATATTACGCAGTAATGGATATTCT
CGTACTCCAATGATAGTGAATCTTCTCACTGGTGGACTTAATATATTTGGTAACTATTGCGCTTTGTATCAACCTTTTGG
ATTGCCTGTTTATGGTGTGCAAGGTGTAGCTGTTGCGACTGCGTTTAGCCAAGTCATTAATACGATTATTTTATGGATAA
TGATCCATAGAAAACACATTGCGCTGCCAATGATGAGCTTTAAAAAAATACCTCAAACAACCTATAAAAAGATCATGCAT
ATTGGGGTAATGAATGCAGGTGAAATGCTCTCATATAACTTGTCACAAATGGTCATTGTTTACTTAGTAGTAAGAATGGG
TACCGCTTCGTTAACCGCTTTTACTTACGCCCAAAATATTGCTCGCGTCTCTTTTGCTTTTGCATTAGCTGTTGGTCAAG
CAAGCCAAATACAAACCAGTTATTACGTAGGAAAAAAATGGATTGAGCAGATTCTTACACGAGTTCAGATCTACTTCTTA
ATCTCTTTTGCTGTCTCTGTTGCCCTTACTTGTATCGTCTTTTTCTTCCGTTATGAATTACTCGACATATTCACACAAGA
TCCAGAGGTCATAACCTTAACAGCAGGATTAATCGCAGGCTCTATTTTAGTGGAAGCTGGACGAGTATTTAACCTTGTCT
TTATATCCGCACTTAAAGGGACTGGTGATATTAAATTTCCAGTTCAATTAGGGATATTAAGCATGTGGGGAGTTGCGGTT
AGTCTGACTTATCTACTTGGCGTTCAGTTTGGTTTTGGTGTACTGGGCGCATGGCTCGCATTAGCTGCAGATGAATGGGT
TCGAGGAGTAATTATGGCTCGCCGCTGGCGCTCTAAAGTATGGACTAAATTTAATCTTATCTAA

Upstream 100 bases:

>100_bases
CAGATTGGGAGAATGAATTTCGTCAAAGTAGACACCTTTATATTTCCTTCCTAGCTGTATGGTGAAGAGCATCCTCTCTT
CCCTTTTTTAAGGACAAACT

Downstream 100 bases:

>100_bases
ATAAAAATGGGCAAAAGTAAATAAATACCTTTGCCCATCCTTTTAGTAAGCTCGGTTATCCTGAGTAAATGACAAATCCA
TCGCTTGAGGTCGGATCCAT

Product: multidrug efflux system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MLDKSNPIERRMQITTLAWPILVEILLRTAISTSDVFMLSGYSDLAVSAIGVISQIIFFLMIISMMVSTGTGILIGQYNG
SGRTQQSTDVAVASVVLGGILGLGLSLFAFFAANPIVIMYGLESDVATFAYDYLIITGSFTLTVTLGIVFSTILRSNGYS
RTPMIVNLLTGGLNIFGNYCALYQPFGLPVYGVQGVAVATAFSQVINTIILWIMIHRKHIALPMMSFKKIPQTTYKKIMH
IGVMNAGEMLSYNLSQMVIVYLVVRMGTASLTAFTYAQNIARVSFAFALAVGQASQIQTSYYVGKKWIEQILTRVQIYFL
ISFAVSVALTCIVFFFRYELLDIFTQDPEVITLTAGLIAGSILVEAGRVFNLVFISALKGTGDIKFPVQLGILSMWGVAV
SLTYLLGVQFGFGVLGAWLALAADEWVRGVIMARRWRSKVWTKFNLI

Sequences:

>Translated_447_residues
MLDKSNPIERRMQITTLAWPILVEILLRTAISTSDVFMLSGYSDLAVSAIGVISQIIFFLMIISMMVSTGTGILIGQYNG
SGRTQQSTDVAVASVVLGGILGLGLSLFAFFAANPIVIMYGLESDVATFAYDYLIITGSFTLTVTLGIVFSTILRSNGYS
RTPMIVNLLTGGLNIFGNYCALYQPFGLPVYGVQGVAVATAFSQVINTIILWIMIHRKHIALPMMSFKKIPQTTYKKIMH
IGVMNAGEMLSYNLSQMVIVYLVVRMGTASLTAFTYAQNIARVSFAFALAVGQASQIQTSYYVGKKWIEQILTRVQIYFL
ISFAVSVALTCIVFFFRYELLDIFTQDPEVITLTAGLIAGSILVEAGRVFNLVFISALKGTGDIKFPVQLGILSMWGVAV
SLTYLLGVQFGFGVLGAWLALAADEWVRGVIMARRWRSKVWTKFNLI
>Mature_447_residues
MLDKSNPIERRMQITTLAWPILVEILLRTAISTSDVFMLSGYSDLAVSAIGVISQIIFFLMIISMMVSTGTGILIGQYNG
SGRTQQSTDVAVASVVLGGILGLGLSLFAFFAANPIVIMYGLESDVATFAYDYLIITGSFTLTVTLGIVFSTILRSNGYS
RTPMIVNLLTGGLNIFGNYCALYQPFGLPVYGVQGVAVATAFSQVINTIILWIMIHRKHIALPMMSFKKIPQTTYKKIMH
IGVMNAGEMLSYNLSQMVIVYLVVRMGTASLTAFTYAQNIARVSFAFALAVGQASQIQTSYYVGKKWIEQILTRVQIYFL
ISFAVSVALTCIVFFFRYELLDIFTQDPEVITLTAGLIAGSILVEAGRVFNLVFISALKGTGDIKFPVQLGILSMWGVAV
SLTYLLGVQFGFGVLGAWLALAADEWVRGVIMARRWRSKVWTKFNLI

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=435, Percent_Identity=25.7471264367816, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49044; Mature: 49044

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKSNPIERRMQITTLAWPILVEILLRTAISTSDVFMLSGYSDLAVSAIGVISQIIFFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
MIISMMVSTGTGILIGQYNGSGRTQQSTDVAVASVVLGGILGLGLSLFAFFAANPIVIMY
HHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GLESDVATFAYDYLIITGSFTLTVTLGIVFSTILRSNGYSRTPMIVNLLTGGLNIFGNYC
ECCCCHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHCHH
ALYQPFGLPVYGVQGVAVATAFSQVINTIILWIMIHRKHIALPMMSFKKIPQTTYKKIMH
HHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHH
IGVMNAGEMLSYNLSQMVIVYLVVRMGTASLTAFTYAQNIARVSFAFALAVGQASQIQTS
HHCCCCCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YYVGKKWIEQILTRVQIYFLISFAVSVALTCIVFFFRYELLDIFTQDPEVITLTAGLIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
SILVEAGRVFNLVFISALKGTGDIKFPVQLGILSMWGVAVSLTYLLGVQFGFGVLGAWLA
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAADEWVRGVIMARRWRSKVWTKFNLI
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDKSNPIERRMQITTLAWPILVEILLRTAISTSDVFMLSGYSDLAVSAIGVISQIIFFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
MIISMMVSTGTGILIGQYNGSGRTQQSTDVAVASVVLGGILGLGLSLFAFFAANPIVIMY
HHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GLESDVATFAYDYLIITGSFTLTVTLGIVFSTILRSNGYSRTPMIVNLLTGGLNIFGNYC
ECCCCHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHCHH
ALYQPFGLPVYGVQGVAVATAFSQVINTIILWIMIHRKHIALPMMSFKKIPQTTYKKIMH
HHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHH
IGVMNAGEMLSYNLSQMVIVYLVVRMGTASLTAFTYAQNIARVSFAFALAVGQASQIQTS
HHCCCCCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YYVGKKWIEQILTRVQIYFLISFAVSVALTCIVFFFRYELLDIFTQDPEVITLTAGLIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
SILVEAGRVFNLVFISALKGTGDIKFPVQLGILSMWGVAVSLTYLLGVQFGFGVLGAWLA
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAADEWVRGVIMARRWRSKVWTKFNLI
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]