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The map label for this gene is 59711816

Identifier: 59711816

GI number: 59711816

Start: 1346409

End: 1347491

Strand: Direct

Name: 59711816

Synonym: VF_1209

Alternate gene names: NA

Gene position: 1346409-1347491 (Clockwise)

Preceding gene: 59711815

Following gene: 59711817

Centisome position: 46.47

GC content: 36.38

Gene sequence:

>1083_bases
ATGGAATTATTATCTATCGACTTTTTAGGTCAGCCACTTCGTTTAGAAGGTTCAATGGCAGGTTGGCAGCAATTATTTTG
GAGTAATACTCTTGTTGCTCAACACGCTGCATCGGCGGATCATAATGATCACTATCATCATGAGTTTCAGTTAACTCAAG
GTGAAAAAATCATCACTTGTCAGTTAGAGGCCAAAGTGACTTGGCAACCATTTCTTATTGAATACCGCGCAATGATTGAT
GGTGAGTTAGTAGCAGAAGGCAGCCGTAACGAAAAAGACATTGAAAAACAGATTCCGCATACTCCTATTAAAGCCGAGCG
TAAATTCAGTTTAATAGGGTTAGTTTCATTAGGAATGAAGGCATTAAAAAGTGCCAAATTAATTAAGGTTGTTTTAGCCT
CTGCAAGTCTTGCTGCATACTCGTGGTTATTCTCTATTGAATTCGCTTTATCTTTGATCGCTTGTTTAATGTTTCATGAG
TATGGACATATAAAAGCGATGAAATATTTTGGAATGAAAACCAAAGGTATTTACCTTATACCATTTTTAGGCGGTTTAGC
TCTGAGTGACGAGAAGATAAATACGCGATGGCAAGATGTTGTTATCTCGATTATGGGGCCATTTTTTGGCTTAATCCTTT
CGCTTATTCTTATGGTGGTATATTGGATAACAGGGGAGATGTTCTTTGCTGGTCTTGCTGTATTCAATGCATTCTTAAAT
TTATTTAATTTATTACCAATACTCCCACTAGATGGTGGGCACGTTTTAAAAAGTATTAGCTTTTCAATGAACAGTAAGCT
TGGTATTTTTTTATGTGCATTAGCAGCTGTTAGTGGTGTCATATTAAGTTACTATTTAGGCCTAGCGCTGTTTGGTTTTT
TACTTATCATGGGTAGTTTAGAAATAGTATTTGAATGGCGAGCTCGTCATCACAGTCATTTATTGCCACTGGATCGATAC
GGACAAATTATTTCATCGGTTTGGTATATAGGATTAGTGAGTTCATTAATTGGCATTATTTGGTATTTTGCAAGTAGCGG
TGATGCTTTGTTGCAATTACCTATGCAAATATTAGGAACTTAA

Upstream 100 bases:

>100_bases
ATTAGAAGAACTAAAAAATATTATCGAAGAAATTTACCCAAATAAAGGTCAACTTTACGTTATCTCTTATCATTTAGTTT
AAAGGAAATAGAGGTCAATA

Downstream 100 bases:

>100_bases
TCTCTAAAATTAAGATTATTAGCTCTTAATAGCTAAAAGGAATTTACGGATGTTTAAAAAATTAAAAGCGTCTCTTGGCA
TTGGTGCCGCAAAAGTGGAT

Product: membrane metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MELLSIDFLGQPLRLEGSMAGWQQLFWSNTLVAQHAASADHNDHYHHEFQLTQGEKIITCQLEAKVTWQPFLIEYRAMID
GELVAEGSRNEKDIEKQIPHTPIKAERKFSLIGLVSLGMKALKSAKLIKVVLASASLAAYSWLFSIEFALSLIACLMFHE
YGHIKAMKYFGMKTKGIYLIPFLGGLALSDEKINTRWQDVVISIMGPFFGLILSLILMVVYWITGEMFFAGLAVFNAFLN
LFNLLPILPLDGGHVLKSISFSMNSKLGIFLCALAAVSGVILSYYLGLALFGFLLIMGSLEIVFEWRARHHSHLLPLDRY
GQIISSVWYIGLVSSLIGIIWYFASSGDALLQLPMQILGT

Sequences:

>Translated_360_residues
MELLSIDFLGQPLRLEGSMAGWQQLFWSNTLVAQHAASADHNDHYHHEFQLTQGEKIITCQLEAKVTWQPFLIEYRAMID
GELVAEGSRNEKDIEKQIPHTPIKAERKFSLIGLVSLGMKALKSAKLIKVVLASASLAAYSWLFSIEFALSLIACLMFHE
YGHIKAMKYFGMKTKGIYLIPFLGGLALSDEKINTRWQDVVISIMGPFFGLILSLILMVVYWITGEMFFAGLAVFNAFLN
LFNLLPILPLDGGHVLKSISFSMNSKLGIFLCALAAVSGVILSYYLGLALFGFLLIMGSLEIVFEWRARHHSHLLPLDRY
GQIISSVWYIGLVSSLIGIIWYFASSGDALLQLPMQILGT
>Mature_360_residues
MELLSIDFLGQPLRLEGSMAGWQQLFWSNTLVAQHAASADHNDHYHHEFQLTQGEKIITCQLEAKVTWQPFLIEYRAMID
GELVAEGSRNEKDIEKQIPHTPIKAERKFSLIGLVSLGMKALKSAKLIKVVLASASLAAYSWLFSIEFALSLIACLMFHE
YGHIKAMKYFGMKTKGIYLIPFLGGLALSDEKINTRWQDVVISIMGPFFGLILSLILMVVYWITGEMFFAGLAVFNAFLN
LFNLLPILPLDGGHVLKSISFSMNSKLGIFLCALAAVSGVILSYYLGLALFGFLLIMGSLEIVFEWRARHHSHLLPLDRY
GQIISSVWYIGLVSSLIGIIWYFASSGDALLQLPMQILGT

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000644
- InterPro:   IPR008915
- InterPro:   IPR016483 [H]

Pfam domain/function: PF00571 CBS; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40243; Mature: 40243

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLSIDFLGQPLRLEGSMAGWQQLFWSNTLVAQHAASADHNDHYHHEFQLTQGEKIITC
CCEEEEECCCCCCEECCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEECCCEEEEE
QLEAKVTWQPFLIEYRAMIDGELVAEGSRNEKDIEKQIPHTPIKAERKFSLIGLVSLGMK
EEEEEECCCHHHHHHHHHHCCHHEECCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ALKSAKLIKVVLASASLAAYSWLFSIEFALSLIACLMFHEYGHIKAMKYFGMKTKGIYLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEE
PFLGGLALSDEKINTRWQDVVISIMGPFFGLILSLILMVVYWITGEMFFAGLAVFNAFLN
EECCCEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFNLLPILPLDGGHVLKSISFSMNSKLGIFLCALAAVSGVILSYYLGLALFGFLLIMGSL
HHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EIVFEWRARHHSHLLPLDRYGQIISSVWYIGLVSSLIGIIWYFASSGDALLQLPMQILGT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MELLSIDFLGQPLRLEGSMAGWQQLFWSNTLVAQHAASADHNDHYHHEFQLTQGEKIITC
CCEEEEECCCCCCEECCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEECCCEEEEE
QLEAKVTWQPFLIEYRAMIDGELVAEGSRNEKDIEKQIPHTPIKAERKFSLIGLVSLGMK
EEEEEECCCHHHHHHHHHHCCHHEECCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ALKSAKLIKVVLASASLAAYSWLFSIEFALSLIACLMFHEYGHIKAMKYFGMKTKGIYLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEE
PFLGGLALSDEKINTRWQDVVISIMGPFFGLILSLILMVVYWITGEMFFAGLAVFNAFLN
EECCCEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFNLLPILPLDGGHVLKSISFSMNSKLGIFLCALAAVSGVILSYYLGLALFGFLLIMGSL
HHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EIVFEWRARHHSHLLPLDRYGQIISSVWYIGLVSSLIGIIWYFASSGDALLQLPMQILGT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]