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The map label for this gene is htpX [H]

Identifier: 59711759

GI number: 59711759

Start: 1277404

End: 1278279

Strand: Direct

Name: htpX [H]

Synonym: VF_1152

Alternate gene names: 59711759

Gene position: 1277404-1278279 (Clockwise)

Preceding gene: 59711757

Following gene: 59711760

Centisome position: 44.09

GC content: 42.81

Gene sequence:

>876_bases
ATGAAGCGTATAGCGCTGTTTTTAGCAACAAACTTAGCGGTAATGATTGTATTCAGTATTGTTCTGAATATCGTTTACGC
GGTTACGGGGATCCAACAAGGTAGTTTATCTGGCTTATTGGTAATGGCAGTATTGTTTGGTTTTGGTGGTTCATTAATTT
CTTTAATGATGTCGAAATCAATGGCACTACGTTCTGTGGGCGGCGAAGTAATTGAACAGCCTCGCAATGAAACAGAACAT
TGGTTATTAGAAACGGTTTCTCGTCAAGCTCAACAGGTTGGTATTGGTATGCCAACGGTTGCTATTTACGATTCACCAGA
CATGAACGCATTTGCTACTGGTGCAAAGCGTGATGATTCATTGGTGGCTGTTTCTACAGGTTTATTGCACAGCATGACTC
GCGATGAAGCTGAAGCGGTATTAGCGCACGAAGTTAGCCACATTGCGAATGGTGATATGATCACGATGACGTTAATGCAA
GGTGTTGTGAATACCTTTGTTATTTTCTTATCTCGTATGATTGCTAATGCGGTAAGTGGCTTTACATCAAGCGATGAAGA
GGGCGAAGGTGAAGGCGGAAGCTTCATGACGTACTTCATTGTGTCTACTGTACTTGAATTAGCGTTTGGCTTCTTAGCAA
GCTTCCTAACGATGTGGTTTAGCCGTCACCGTGAATTCCATGCGGATGCGGGTGCTGCTCAGTTAGTTGGTAAACAAAAA
ATGATTGCAGCTCTTGAACGTTTACGTATGGGGCAGGAGTCTCAGCTAGAAGGTTCTATGATGGCATTTGGTATCAACGG
TAAAAAATCGTTAACCGAATTGTTGATGAGCCACCCACCTCTAGAGAAACGTATTGACGCTCTTCGTCAAATGTAA

Upstream 100 bases:

>100_bases
TTATGCCTGATTTATCGTGCTAGAAACGATAATCAGGGGTCTGCTCAACAAGACGATATACAAAAAATGAGCAGGTTGAA
TTAATTATTGGAGTAAAGAA

Downstream 100 bases:

>100_bases
TCTTTAATTTAAAGATAAAAACCCGAGGCTTTCTCGGGTTTTTTTATATGTATAGATCACATAAATCTTTTACCAAAGAT
GATTACAAGTTATAGTCTGC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKRIALFLATNLAVMIVFSIVLNIVYAVTGIQQGSLSGLLVMAVLFGFGGSLISLMMSKSMALRSVGGEVIEQPRNETEH
WLLETVSRQAQQVGIGMPTVAIYDSPDMNAFATGAKRDDSLVAVSTGLLHSMTRDEAEAVLAHEVSHIANGDMITMTLMQ
GVVNTFVIFLSRMIANAVSGFTSSDEEGEGEGGSFMTYFIVSTVLELAFGFLASFLTMWFSRHREFHADAGAAQLVGKQK
MIAALERLRMGQESQLEGSMMAFGINGKKSLTELLMSHPPLEKRIDALRQM

Sequences:

>Translated_291_residues
MKRIALFLATNLAVMIVFSIVLNIVYAVTGIQQGSLSGLLVMAVLFGFGGSLISLMMSKSMALRSVGGEVIEQPRNETEH
WLLETVSRQAQQVGIGMPTVAIYDSPDMNAFATGAKRDDSLVAVSTGLLHSMTRDEAEAVLAHEVSHIANGDMITMTLMQ
GVVNTFVIFLSRMIANAVSGFTSSDEEGEGEGGSFMTYFIVSTVLELAFGFLASFLTMWFSRHREFHADAGAAQLVGKQK
MIAALERLRMGQESQLEGSMMAFGINGKKSLTELLMSHPPLEKRIDALRQM
>Mature_291_residues
MKRIALFLATNLAVMIVFSIVLNIVYAVTGIQQGSLSGLLVMAVLFGFGGSLISLMMSKSMALRSVGGEVIEQPRNETEH
WLLETVSRQAQQVGIGMPTVAIYDSPDMNAFATGAKRDDSLVAVSTGLLHSMTRDEAEAVLAHEVSHIANGDMITMTLMQ
GVVNTFVIFLSRMIANAVSGFTSSDEEGEGEGGSFMTYFIVSTVLELAFGFLASFLTMWFSRHREFHADAGAAQLVGKQK
MIAALERLRMGQESQLEGSMMAFGINGKKSLTELLMSHPPLEKRIDALRQM

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=291, Percent_Identity=68.3848797250859, Blast_Score=403, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 31611; Mature: 31611

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.2 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.2 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIALFLATNLAVMIVFSIVLNIVYAVTGIQQGSLSGLLVMAVLFGFGGSLISLMMSKS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
MALRSVGGEVIEQPRNETEHWLLETVSRQAQQVGIGMPTVAIYDSPDMNAFATGAKRDDS
HHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCCCCCC
LVAVSTGLLHSMTRDEAEAVLAHEVSHIANGDMITMTLMQGVVNTFVIFLSRMIANAVSG
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FTSSDEEGEGEGGSFMTYFIVSTVLELAFGFLASFLTMWFSRHREFHADAGAAQLVGKQK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
MIAALERLRMGQESQLEGSMMAFGINGKKSLTELLMSHPPLEKRIDALRQM
HHHHHHHHHCCCCHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKRIALFLATNLAVMIVFSIVLNIVYAVTGIQQGSLSGLLVMAVLFGFGGSLISLMMSKS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
MALRSVGGEVIEQPRNETEHWLLETVSRQAQQVGIGMPTVAIYDSPDMNAFATGAKRDDS
HHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCCCCCC
LVAVSTGLLHSMTRDEAEAVLAHEVSHIANGDMITMTLMQGVVNTFVIFLSRMIANAVSG
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FTSSDEEGEGEGGSFMTYFIVSTVLELAFGFLASFLTMWFSRHREFHADAGAAQLVGKQK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
MIAALERLRMGQESQLEGSMMAFGINGKKSLTELLMSHPPLEKRIDALRQM
HHHHHHHHHCCCCHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA