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The map label for this gene is yafC [C]

Identifier: 59711673

GI number: 59711673

Start: 1179403

End: 1180305

Strand: Reverse

Name: yafC [C]

Synonym: VF_1066

Alternate gene names: 59711673

Gene position: 1180305-1179403 (Counterclockwise)

Preceding gene: 59711676

Following gene: 59711669

Centisome position: 40.73

GC content: 38.43

Gene sequence:

>903_bases
ATGGGGCAATTAGAAAGCATGCGAATTTTTATTACTGTTGTTGAAACTGGCAGTATAACCAAAGCAGCAGAGCGCCTTAA
TCTTGCCAAATCAGCCATCAGTAAACGTCTTAGTGAGTTAGAGCACCAACTCGGAGTTAAACTACTTAATCGAACAACCC
GAACATCAAGCTTGACTGAAGCTGGTCAAGTTTATTTGAATAAATGTAAATTAATTTTGGATGAAGTGGACGATCTACAT
TGTCATATATCATCGACTAGTAGCAAATTAAATGGTGTATTAAAGCTAGCGGTTCCATTGACCTTTGGACTCAAGCACCT
TGTTCCTGCCCTCGACAATTTTGCAAAGTTACATCCTGAGCTAAAATTAGATATCGATTTTTCGGATAAAAAAATAGATT
TGGTTGAAGATGGGGTTGATTTGGCGATTCGAATTGGCTCTTTGAGTAATTCAACTTTACGAGCGAAACCACTCGCCCCT
ATCCATCATGTATTATGTGTAAGTCCAGATTACCTAACGGAACATGGACATATCACAACACCTAATGATCTAAAATCTCA
TAAATTATTAAGGTATAGCCAACAACCACTGTCCGGTGTTGAGTTAATAGATAACAATAACAAAACAATGACCGTTCCGA
TGGAAAGCTTTTGTATCGCAAATAATGGGGATTTTCTAAAAACAATGGCGGTATCTGGACATGGCGTATTATTCACACCA
AAATTTATTGTCTGGGAAGAGCTAGCAAATGGCTCCCTAATACCAATCATGACCGATTATCGCTTCAACTCTATTAAGGC
TTATGCCGTTTACCCAGAGACCCGCTACCTACCTCGAAAAGTTCGAATGTTAATCGACTTTTTAAGTGAATATTTTGGTA
ACGAGCCCTACTGGGATAAGTAA

Upstream 100 bases:

>100_bases
CTTGGTATAAAGAATAGTCATTGAAGAAATCTTGATAAACAGCAATACTGAGGAAACACTGTTCTCATTTAGAGAACAAT
AAAAAAATAAAGGAATGGAT

Downstream 100 bases:

>100_bases
TTAAACGAAATTAATACAGCACCATCGCCAAATAACCTAATACAAGAACAATCATTGATGTTAATGCATAAGGAACAGGG
TAGCCTACTGCAGGCATATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MGQLESMRIFITVVETGSITKAAERLNLAKSAISKRLSELEHQLGVKLLNRTTRTSSLTEAGQVYLNKCKLILDEVDDLH
CHISSTSSKLNGVLKLAVPLTFGLKHLVPALDNFAKLHPELKLDIDFSDKKIDLVEDGVDLAIRIGSLSNSTLRAKPLAP
IHHVLCVSPDYLTEHGHITTPNDLKSHKLLRYSQQPLSGVELIDNNNKTMTVPMESFCIANNGDFLKTMAVSGHGVLFTP
KFIVWEELANGSLIPIMTDYRFNSIKAYAVYPETRYLPRKVRMLIDFLSEYFGNEPYWDK

Sequences:

>Translated_300_residues
MGQLESMRIFITVVETGSITKAAERLNLAKSAISKRLSELEHQLGVKLLNRTTRTSSLTEAGQVYLNKCKLILDEVDDLH
CHISSTSSKLNGVLKLAVPLTFGLKHLVPALDNFAKLHPELKLDIDFSDKKIDLVEDGVDLAIRIGSLSNSTLRAKPLAP
IHHVLCVSPDYLTEHGHITTPNDLKSHKLLRYSQQPLSGVELIDNNNKTMTVPMESFCIANNGDFLKTMAVSGHGVLFTP
KFIVWEELANGSLIPIMTDYRFNSIKAYAVYPETRYLPRKVRMLIDFLSEYFGNEPYWDK
>Mature_299_residues
GQLESMRIFITVVETGSITKAAERLNLAKSAISKRLSELEHQLGVKLLNRTTRTSSLTEAGQVYLNKCKLILDEVDDLHC
HISSTSSKLNGVLKLAVPLTFGLKHLVPALDNFAKLHPELKLDIDFSDKKIDLVEDGVDLAIRIGSLSNSTLRAKPLAPI
HHVLCVSPDYLTEHGHITTPNDLKSHKLLRYSQQPLSGVELIDNNNKTMTVPMESFCIANNGDFLKTMAVSGHGVLFTPK
FIVWEELANGSLIPIMTDYRFNSIKAYAVYPETRYLPRKVRMLIDFLSEYFGNEPYWDK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=34.8122866894198, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=32.4232081911263, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=34.8122866894198, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=26.9230769230769, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=30.4794520547945, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=26.8041237113402, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787128, Length=282, Percent_Identity=24.113475177305, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789173, Length=260, Percent_Identity=28.8461538461538, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788706, Length=294, Percent_Identity=26.8707482993197, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786448, Length=274, Percent_Identity=26.6423357664234, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=152, Percent_Identity=32.2368421052632, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693105, Length=191, Percent_Identity=25.6544502617801, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790783, Length=289, Percent_Identity=24.2214532871972, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790262, Length=198, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=29.8387096774194, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790011, Length=289, Percent_Identity=21.1072664359862, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788748, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33665; Mature: 33534

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQLESMRIFITVVETGSITKAAERLNLAKSAISKRLSELEHQLGVKLLNRTTRTSSLTE
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AGQVYLNKCKLILDEVDDLHCHISSTSSKLNGVLKLAVPLTFGLKHLVPALDNFAKLHPE
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
LKLDIDFSDKKIDLVEDGVDLAIRIGSLSNSTLRAKPLAPIHHVLCVSPDYLTEHGHITT
EEEEEECCCCEEEEEECCCEEEEEEECCCCCCEECCCCCHHHHHEECCCCHHHCCCCCCC
PNDLKSHKLLRYSQQPLSGVELIDNNNKTMTVPMESFCIANNGDFLKTMAVSGHGVLFTP
CCCHHHHHHHHHCCCCCCCEEEEECCCCEEEEEHHHEEEECCCCEEEEEEECCCCEEECC
KFIVWEELANGSLIPIMTDYRFNSIKAYAVYPETRYLPRKVRMLIDFLSEYFGNEPYWDK
HHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GQLESMRIFITVVETGSITKAAERLNLAKSAISKRLSELEHQLGVKLLNRTTRTSSLTE
CCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AGQVYLNKCKLILDEVDDLHCHISSTSSKLNGVLKLAVPLTFGLKHLVPALDNFAKLHPE
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
LKLDIDFSDKKIDLVEDGVDLAIRIGSLSNSTLRAKPLAPIHHVLCVSPDYLTEHGHITT
EEEEEECCCCEEEEEECCCEEEEEEECCCCCCEECCCCCHHHHHEECCCCHHHCCCCCCC
PNDLKSHKLLRYSQQPLSGVELIDNNNKTMTVPMESFCIANNGDFLKTMAVSGHGVLFTP
CCCHHHHHHHHHCCCCCCCEEEEECCCCEEEEEHHHEEEECCCCEEEEEEECCCCEEECC
KFIVWEELANGSLIPIMTDYRFNSIKAYAVYPETRYLPRKVRMLIDFLSEYFGNEPYWDK
HHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]