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The map label for this gene is ycgM [H]

Identifier: 59711665

GI number: 59711665

Start: 1168054

End: 1168668

Strand: Reverse

Name: ycgM [H]

Synonym: VF_1058

Alternate gene names: 59711665

Gene position: 1168668-1168054 (Counterclockwise)

Preceding gene: 59711669

Following gene: 59711664

Centisome position: 40.33

GC content: 36.26

Gene sequence:

>615_bases
ATGAATACCATTCGTTTTGGAGAGCAGCTGATCACCCCAACTAAGTTGCTGTGTATCGGTCGCAATTATATTGATCATAT
TAGTGAACTTAATAATTCGATTCCTGATCAAATGGTGGTATTTAATAAACCCAATTCCTGCATCACTTCTACTTTAAGTT
CATTCCATCAAGAACGCTTACATTATGAAGCTGAAATTTGTTTCCTAATTAAAGATGAACAATTAAATGCAGTGGCCATT
GGGCTCGATTTAACCAAACGTGACTTACAAGCTGAACTTAAAAGTAAAGGATTACCTTGGGAACGAGCAAAAGCGTTTAA
TGGTTCTGCTATCTTCAGCCGTTTTATCCCTATTGATAACCTTAATATCGATGCACTCCAAATCGAATTATTTATTAATA
GTATGCGAGTTCAATGTGGCAACGTAAGCCAAATGATTTATTCTCCTGAAACGATTTTAAATGACTTAAAAAGTTATACC
CAATTATGTGATGGTGATGTCGTTATGACAGGCACCCCACAAGGTGTAGGCGAAATACACATGGGGGATATCTTTCTTGC
TCGATTAAAATTAGATGGAAAAACACTAATAGAAACGGAATGGGTTGCAAGGTAA

Upstream 100 bases:

>100_bases
TAGCTAAATGTCGAATTTTTAATAAATACTCATAAAATTAAACGTAATTGAAATAATTTCACGATACAATTTCGAATTAT
TTTTGTGCTAAGGAAAAGCA

Downstream 100 bases:

>100_bases
CGTCTTTAATTAAATACAATTAACAATCAATAGCACAACCATATATTAACAATATTATTTATAATATTTAATATGCTGAT
TTTTTATTCTATTTTGAATC

Product: isomerase/hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MNTIRFGEQLITPTKLLCIGRNYIDHISELNNSIPDQMVVFNKPNSCITSTLSSFHQERLHYEAEICFLIKDEQLNAVAI
GLDLTKRDLQAELKSKGLPWERAKAFNGSAIFSRFIPIDNLNIDALQIELFINSMRVQCGNVSQMIYSPETILNDLKSYT
QLCDGDVVMTGTPQGVGEIHMGDIFLARLKLDGKTLIETEWVAR

Sequences:

>Translated_204_residues
MNTIRFGEQLITPTKLLCIGRNYIDHISELNNSIPDQMVVFNKPNSCITSTLSSFHQERLHYEAEICFLIKDEQLNAVAI
GLDLTKRDLQAELKSKGLPWERAKAFNGSAIFSRFIPIDNLNIDALQIELFINSMRVQCGNVSQMIYSPETILNDLKSYT
QLCDGDVVMTGTPQGVGEIHMGDIFLARLKLDGKTLIETEWVAR
>Mature_204_residues
MNTIRFGEQLITPTKLLCIGRNYIDHISELNNSIPDQMVVFNKPNSCITSTLSSFHQERLHYEAEICFLIKDEQLNAVAI
GLDLTKRDLQAELKSKGLPWERAKAFNGSAIFSRFIPIDNLNIDALQIELFINSMRVQCGNVSQMIYSPETILNDLKSYT
QLCDGDVVMTGTPQGVGEIHMGDIFLARLKLDGKTLIETEWVAR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=184, Percent_Identity=32.6086956521739, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI13654274, Length=184, Percent_Identity=32.6086956521739, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI66348062, Length=184, Percent_Identity=32.6086956521739, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI156231349, Length=205, Percent_Identity=26.8292682926829, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI40786394, Length=205, Percent_Identity=25.8536585365854, Blast_Score=78, Evalue=6e-15,
Organism=Escherichia coli, GI1787428, Length=202, Percent_Identity=33.1683168316832, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17557057, Length=188, Percent_Identity=35.1063829787234, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324161, Length=217, Percent_Identity=32.258064516129, Blast_Score=106, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28572127, Length=188, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571789, Length=193, Percent_Identity=27.4611398963731, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23023; Mature: 23023

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIRFGEQLITPTKLLCIGRNYIDHISELNNSIPDQMVVFNKPNSCITSTLSSFHQERL
CCCCCCCHHHCCCHHEEEECCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
HYEAEICFLIKDEQLNAVAIGLDLTKRDLQAELKSKGLPWERAKAFNGSAIFSRFIPIDN
CEEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHCCCCCC
LNIDALQIELFINSMRVQCGNVSQMIYSPETILNDLKSYTQLCDGDVVMTGTPQGVGEIH
CCCCCEEEEEEEEHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEE
MGDIFLARLKLDGKTLIETEWVAR
ECCEEEEEEEECCCEEECCCCCCC
>Mature Secondary Structure
MNTIRFGEQLITPTKLLCIGRNYIDHISELNNSIPDQMVVFNKPNSCITSTLSSFHQERL
CCCCCCCHHHCCCHHEEEECCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
HYEAEICFLIKDEQLNAVAIGLDLTKRDLQAELKSKGLPWERAKAFNGSAIFSRFIPIDN
CEEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHCCCCCC
LNIDALQIELFINSMRVQCGNVSQMIYSPETILNDLKSYTQLCDGDVVMTGTPQGVGEIH
CCCCCEEEEEEEEHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEE
MGDIFLARLKLDGKTLIETEWVAR
ECCEEEEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]