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The map label for this gene is hlyB [H]

Identifier: 59711594

GI number: 59711594

Start: 1085721

End: 1087673

Strand: Direct

Name: hlyB [H]

Synonym: VF_0987

Alternate gene names: 59711594

Gene position: 1085721-1087673 (Clockwise)

Preceding gene: 59711592

Following gene: 59711595

Centisome position: 37.47

GC content: 36.51

Gene sequence:

>1953_bases
ATGGGTTTGCTCCTTCAATATTATCGTAATTCTTTACAACTACGCTATCAGCTAATGGTTCCATTTATTGGTACCTTTAT
AATATTCTTTTGTAGTGCTACATTTTTGCATACAAACCTTATTCGCACAGAAAATAATATTATGTCTTCAATGGTGAGTA
ATACTATTTCTGAAGACTATATTGAACTGGATAATTTGTTTTCGAGATTAAGAACTGCTGCAATTCGTAGTGAAATGTTC
GATCCTGAGAGAGGACAAAAGGAATATAACGAAGCTTATCCTAAGATCTTAGAAGATAAAGACAAAGTGATTACTCGTTT
AAGAAATATGGGGGAGTTAACTCGTCAGGATCTAAATGATTTAGAAAGAATTTCTCAATCTTTTGATGAATTTCATTCTA
TTTCAAAGAAGATGATTGATGAAAAAGTAGACGGACATAATATATTTTTAAACGTCTTGCCGTGGTTAGCTCCTTATTTA
GATAATTTAGACGAGAATCATCATCCATCAAATGCGGATGAATGGCCTATTATTCGTAATAAGCTATCGGTGATATCTGA
AGGGATTGGGTATAAATCTTCAGGTGTGTTTTATTTGCGTCTACAAGAAGATGGTGATGAGCTTCATGCATTGCTAGACC
AAATGGAAGAATTGATTGAGCCAATGTATAAGGGCCCGGCTCTAAAGAAATTACAGACTGAATTTCTTGATGTATGGCGT
AAAGAACTGACAACGTTAGAAAATATTACGTCGCGTTGGGTTGGGTACCAAGCTAAGCGTGCTGAAATTAGAAGTGTTGC
TCGAGAACTAATTGATAATTCAGTTGCAAGCAGTAAAAAGTACTTAGAAAAGAACTTTAATAATACAATAGAAAATGCCG
AAAATAGTATTGTTGTCAACATTGTTGGTTTATTAATTGGTGCTGTATTGGCTTCTATTCTAGTTACTATTTTAACTCGT
ATCATTATTTCTCAGTTAAACTCAGTACAAAGTGTTATTCGTGGTTTAGCTGAACGTAATTTGATCTTTCATACCAATTT
AAAAGGTGAGAATGAAGTTTCTCAGCTTGGCGAGAATACCGATATAACGATTAATACGCTAAGAGGAACAATTAAAGACC
TAAACTCACATGGTCAAGAATTGGCATCTGCATCATTGCAATTACGTTCAGTTATGGAATTAAGTGCAGAAAACAGTAGT
GTTCAAAATGATCAAGTGAGCATGATTGCTGCAGCAATTACAGAACTATCGGCATCTGCAAATCAAGTTGAAGCATCAGC
GAAAGCGGCGGAAACAAGAATGGGGGGTGTACAAGAGTTATGTCGCTTAGAGATGCGTTCTTCACGTGAAAATGGTGATC
GCGCTAGTGCTTTGCAAGAGCAATTAAATGATACGTCTTTAGTGGTTGAGCATCTAAATAAAGAATGTGAGCAAATTGGT
AATGTTATTGCCGTGATTCAGAATATTTCTGAGCAAACTAACTTACTTGCACTTAATGCTGCAATTGAAGCAGCTCGAGC
TGGTGAAATGGGGCGTGGTTTTGCTGTCGTTGCTGATGAAGTTCGAGTACTAGCAACAAGAACACAAGACTCAACGGAAA
CCATTCAACGAATTATTGAACAACTGCAAAGTAAATCGACAGATGCTCAGCAAAATATGCAACGTTGTTTATCTATGATT
GATGAAACTGCAGCATCAGTATTAAAGTCACGCGATCAATTGTCGTCAATGAATGAAGCGATGGATGAGTTATCACAATC
GAATGCTGAAGTAGCAACGGCGGTTTCTGAGCAATCACGTACTATGGTTGAAATTAGCGAGAATATTACAACAATTCGAG
ACATTACTAACCAAAATGTTGCGGGCATTGAAGAAGCAACAGTGACAAGTACGCACCTATCAGAGCTAGCTGAAAAACAA
CAGCAACAATTGGCTACTTTTAGAGTTGATTAA

Upstream 100 bases:

>100_bases
AGCGCGATAACGTTAATTAGTTAAGGGAAGCGTTTTAGTTATTAGTATTCATTCTTCATGGTTGAGTTTATGAATGAACT
TACTTTTATAAGGTATATAA

Downstream 100 bases:

>100_bases
AGGACTTAAAACATCATAAAACTAAGTGGGTGAGAAATAATTATTTCTTGCCCATTTTTTTATTAAGAACAAAAAATGAA
ATAAGGCTAAAGGAAATCGT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MGLLLQYYRNSLQLRYQLMVPFIGTFIIFFCSATFLHTNLIRTENNIMSSMVSNTISEDYIELDNLFSRLRTAAIRSEMF
DPERGQKEYNEAYPKILEDKDKVITRLRNMGELTRQDLNDLERISQSFDEFHSISKKMIDEKVDGHNIFLNVLPWLAPYL
DNLDENHHPSNADEWPIIRNKLSVISEGIGYKSSGVFYLRLQEDGDELHALLDQMEELIEPMYKGPALKKLQTEFLDVWR
KELTTLENITSRWVGYQAKRAEIRSVARELIDNSVASSKKYLEKNFNNTIENAENSIVVNIVGLLIGAVLASILVTILTR
IIISQLNSVQSVIRGLAERNLIFHTNLKGENEVSQLGENTDITINTLRGTIKDLNSHGQELASASLQLRSVMELSAENSS
VQNDQVSMIAAAITELSASANQVEASAKAAETRMGGVQELCRLEMRSSRENGDRASALQEQLNDTSLVVEHLNKECEQIG
NVIAVIQNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRVLATRTQDSTETIQRIIEQLQSKSTDAQQNMQRCLSMI
DETAASVLKSRDQLSSMNEAMDELSQSNAEVATAVSEQSRTMVEISENITTIRDITNQNVAGIEEATVTSTHLSELAEKQ
QQQLATFRVD

Sequences:

>Translated_650_residues
MGLLLQYYRNSLQLRYQLMVPFIGTFIIFFCSATFLHTNLIRTENNIMSSMVSNTISEDYIELDNLFSRLRTAAIRSEMF
DPERGQKEYNEAYPKILEDKDKVITRLRNMGELTRQDLNDLERISQSFDEFHSISKKMIDEKVDGHNIFLNVLPWLAPYL
DNLDENHHPSNADEWPIIRNKLSVISEGIGYKSSGVFYLRLQEDGDELHALLDQMEELIEPMYKGPALKKLQTEFLDVWR
KELTTLENITSRWVGYQAKRAEIRSVARELIDNSVASSKKYLEKNFNNTIENAENSIVVNIVGLLIGAVLASILVTILTR
IIISQLNSVQSVIRGLAERNLIFHTNLKGENEVSQLGENTDITINTLRGTIKDLNSHGQELASASLQLRSVMELSAENSS
VQNDQVSMIAAAITELSASANQVEASAKAAETRMGGVQELCRLEMRSSRENGDRASALQEQLNDTSLVVEHLNKECEQIG
NVIAVIQNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRVLATRTQDSTETIQRIIEQLQSKSTDAQQNMQRCLSMI
DETAASVLKSRDQLSSMNEAMDELSQSNAEVATAVSEQSRTMVEISENITTIRDITNQNVAGIEEATVTSTHLSELAEKQ
QQQLATFRVD
>Mature_649_residues
GLLLQYYRNSLQLRYQLMVPFIGTFIIFFCSATFLHTNLIRTENNIMSSMVSNTISEDYIELDNLFSRLRTAAIRSEMFD
PERGQKEYNEAYPKILEDKDKVITRLRNMGELTRQDLNDLERISQSFDEFHSISKKMIDEKVDGHNIFLNVLPWLAPYLD
NLDENHHPSNADEWPIIRNKLSVISEGIGYKSSGVFYLRLQEDGDELHALLDQMEELIEPMYKGPALKKLQTEFLDVWRK
ELTTLENITSRWVGYQAKRAEIRSVARELIDNSVASSKKYLEKNFNNTIENAENSIVVNIVGLLIGAVLASILVTILTRI
IISQLNSVQSVIRGLAERNLIFHTNLKGENEVSQLGENTDITINTLRGTIKDLNSHGQELASASLQLRSVMELSAENSSV
QNDQVSMIAAAITELSASANQVEASAKAAETRMGGVQELCRLEMRSSRENGDRASALQEQLNDTSLVVEHLNKECEQIGN
VIAVIQNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRVLATRTQDSTETIQRIIEQLQSKSTDAQQNMQRCLSMID
ETAASVLKSRDQLSSMNEAMDELSQSNAEVATAVSEQSRTMVEISENITTIRDITNQNVAGIEEATVTSTHLSELAEKQQ
QQLATFRVD

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=351, Percent_Identity=28.2051282051282, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788194, Length=365, Percent_Identity=26.8493150684932, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1789453, Length=449, Percent_Identity=26.0579064587973, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788195, Length=341, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI2367378, Length=303, Percent_Identity=29.7029702970297, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72918; Mature: 72787

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLLQYYRNSLQLRYQLMVPFIGTFIIFFCSATFLHTNLIRTENNIMSSMVSNTISEDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IELDNLFSRLRTAAIRSEMFDPERGQKEYNEAYPKILEDKDKVITRLRNMGELTRQDLND
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LERISQSFDEFHSISKKMIDEKVDGHNIFLNVLPWLAPYLDNLDENHHPSNADEWPIIRN
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
KLSVISEGIGYKSSGVFYLRLQEDGDELHALLDQMEELIEPMYKGPALKKLQTEFLDVWR
HHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KELTTLENITSRWVGYQAKRAEIRSVARELIDNSVASSKKYLEKNFNNTIENAENSIVVN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHH
IVGLLIGAVLASILVTILTRIIISQLNSVQSVIRGLAERNLIFHTNLKGENEVSQLGENT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCC
DITINTLRGTIKDLNSHGQELASASLQLRSVMELSAENSSVQNDQVSMIAAAITELSASA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCH
NQVEASAKAAETRMGGVQELCRLEMRSSRENGDRASALQEQLNDTSLVVEHLNKECEQIG
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
NVIAVIQNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRVLATRTQDSTETIQRIIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
QLQSKSTDAQQNMQRCLSMIDETAASVLKSRDQLSSMNEAMDELSQSNAEVATAVSEQSR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TMVEISENITTIRDITNQNVAGIEEATVTSTHLSELAEKQQQQLATFRVD
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLLLQYYRNSLQLRYQLMVPFIGTFIIFFCSATFLHTNLIRTENNIMSSMVSNTISEDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IELDNLFSRLRTAAIRSEMFDPERGQKEYNEAYPKILEDKDKVITRLRNMGELTRQDLND
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LERISQSFDEFHSISKKMIDEKVDGHNIFLNVLPWLAPYLDNLDENHHPSNADEWPIIRN
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
KLSVISEGIGYKSSGVFYLRLQEDGDELHALLDQMEELIEPMYKGPALKKLQTEFLDVWR
HHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KELTTLENITSRWVGYQAKRAEIRSVARELIDNSVASSKKYLEKNFNNTIENAENSIVVN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHH
IVGLLIGAVLASILVTILTRIIISQLNSVQSVIRGLAERNLIFHTNLKGENEVSQLGENT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCC
DITINTLRGTIKDLNSHGQELASASLQLRSVMELSAENSSVQNDQVSMIAAAITELSASA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCH
NQVEASAKAAETRMGGVQELCRLEMRSSRENGDRASALQEQLNDTSLVVEHLNKECEQIG
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
NVIAVIQNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRVLATRTQDSTETIQRIIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
QLQSKSTDAQQNMQRCLSMIDETAASVLKSRDQLSSMNEAMDELSQSNAEVATAVSEQSR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TMVEISENITTIRDITNQNVAGIEEATVTSTHLSELAEKQQQQLATFRVD
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]