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The map label for this gene is lolA

Identifier: 59711513

GI number: 59711513

Start: 1000417

End: 1001013

Strand: Direct

Name: lolA

Synonym: VF_0906

Alternate gene names: 59711513

Gene position: 1000417-1001013 (Clockwise)

Preceding gene: 59711512

Following gene: 59711514

Centisome position: 34.53

GC content: 38.53

Gene sequence:

>597_bases
ATGAAAAAGTTTTTATTTTCTCTCTGTTTATTAAGTTCGACGGTATTGGCATCACCTCAAAGTGAACTAACAGAACGATT
GAACCAGAATGCAGGCTTTGAAGCTGGTTTTACACAAAAAGTATTAAGCCCAGAAGGTGATGTACTAATGCAAGGCGAGG
GTGATGTGAAAATCCTGCGTCCTAATTTGTTTCGTTGGCATACACAAACGCCTGATGAAAACCTATTAGTTACCGATGGT
AACACCTTGTGGTATTACAACCCATTTGTTGAGCAAGTAACATTAATGGGGTTAGAGAAAGCAACAACTCAAACACCATT
CGTATTATTAACTCGTAATAAAGCGTCGGATTGGGACAATTATTCAGTGAGCCAAAATGGTGATGCGTTTACGGTTTCAC
CAAAAGCAGATTCTGCTGTAAAAAGTGAATTTATTGTTCGCATCCAAGAAAACGGCAAAGTAACGGGTTTTTCGGTTGTT
GAGCAAGACGGCCAACGTAGTGATTTTGACTTCACAAAATTTGAAGCAAAGAAGCCTGCTAAAGATAATTTTACATTTGC
GATTCCTGATGGTGTAGATATTGACGATCAACGTTAA

Upstream 100 bases:

>100_bases
GGCATTGTTAGTACTCCGGGTCACAATGGTAACCGTGAAGTAATTGCACCGCCTCCTGTAGGTATGCACGATTAATCCAA
ATTTTTAGAAGTGAAGTGTA

Downstream 100 bases:

>100_bases
TAAGCGTGCATCTAAGAAACTAAAAGGATAAACGTGAGTAATTTCAGTTTAGATTTTTCAGCAGGGGACGATTATCGTCC
CCTTGCTGCTAGAATGCGTC

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKKFLFSLCLLSSTVLASPQSELTERLNQNAGFEAGFTQKVLSPEGDVLMQGEGDVKILRPNLFRWHTQTPDENLLVTDG
NTLWYYNPFVEQVTLMGLEKATTQTPFVLLTRNKASDWDNYSVSQNGDAFTVSPKADSAVKSEFIVRIQENGKVTGFSVV
EQDGQRSDFDFTKFEAKKPAKDNFTFAIPDGVDIDDQR

Sequences:

>Translated_198_residues
MKKFLFSLCLLSSTVLASPQSELTERLNQNAGFEAGFTQKVLSPEGDVLMQGEGDVKILRPNLFRWHTQTPDENLLVTDG
NTLWYYNPFVEQVTLMGLEKATTQTPFVLLTRNKASDWDNYSVSQNGDAFTVSPKADSAVKSEFIVRIQENGKVTGFSVV
EQDGQRSDFDFTKFEAKKPAKDNFTFAIPDGVDIDDQR
>Mature_198_residues
MKKFLFSLCLLSSTVLASPQSELTERLNQNAGFEAGFTQKVLSPEGDVLMQGEGDVKILRPNLFRWHTQTPDENLLVTDG
NTLWYYNPFVEQVTLMGLEKATTQTPFVLLTRNKASDWDNYSVSQNGDAFTVSPKADSAVKSEFIVRIQENGKVTGFSVV
EQDGQRSDFDFTKFEAKKPAKDNFTFAIPDGVDIDDQR

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=202, Percent_Identity=45.049504950495, Blast_Score=187, Evalue=3e-49,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_VIBF1 (Q5E6E5)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_204289.1
- ProteinModelPortal:   Q5E6E5
- SMR:   Q5E6E5
- STRING:   Q5E6E5
- GeneID:   3278198
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0906
- NMPDR:   fig|312309.3.peg.754
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- PhylomeDB:   Q5E6E5
- ProtClustDB:   PRK00031
- BioCyc:   VFIS312309:VF0906-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22217; Mature: 22217

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLFSLCLLSSTVLASPQSELTERLNQNAGFEAGFTQKVLSPEGDVLMQGEGDVKILR
CHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEEECCCCEEEEC
PNLFRWHTQTPDENLLVTDGNTLWYYNPFVEQVTLMGLEKATTQTPFVLLTRNKASDWDN
CCEEEEECCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
YSVSQNGDAFTVSPKADSAVKSEFIVRIQENGKVTGFSVVEQDGQRSDFDFTKFEAKKPA
CEECCCCCEEEECCCCCCHHCCEEEEEECCCCCEEEEEEECCCCCCCCCCCEEECCCCCC
KDNFTFAIPDGVDIDDQR
CCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MKKFLFSLCLLSSTVLASPQSELTERLNQNAGFEAGFTQKVLSPEGDVLMQGEGDVKILR
CHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEEECCCCEEEEC
PNLFRWHTQTPDENLLVTDGNTLWYYNPFVEQVTLMGLEKATTQTPFVLLTRNKASDWDN
CCEEEEECCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
YSVSQNGDAFTVSPKADSAVKSEFIVRIQENGKVTGFSVVEQDGQRSDFDFTKFEAKKPA
CEECCCCCEEEECCCCCCHHCCEEEEEECCCCCEEEEEEECCCCCCCCCCCEEECCCCCC
KDNFTFAIPDGVDIDDQR
CCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA