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The map label for this gene is clpX

Identifier: 59711404

GI number: 59711404

Start: 871954

End: 873240

Strand: Direct

Name: clpX

Synonym: VF_0797

Alternate gene names: 59711404

Gene position: 871954-873240 (Clockwise)

Preceding gene: 59711403

Following gene: 59711405

Centisome position: 30.09

GC content: 38.31

Gene sequence:

>1287_bases
ATGACAGACAAGCGTAAAGACGAAAATAGTGGAAAGTTACTATATTGCTCTTTTTGCGGAAAAAGCCAGCATGAAGTTCG
TAAACTAATTGCAGGCCCATCTGTTTATGTTTGTGATGAGTGCGTTGATTTATGTAACGACATTATTCGCGAAGAGCTAA
AAGATAATACTCTGTCTCCTAAAGAGAGTAGTGAAGAGTTACCAACACCACGTAATATTCGTGAGCATTTAGATGACTAT
GTAATTGGTCAAGAACATGCGAAGAAAGTACTGGCTGTTGCTGTATACAACCACTACAAGCGTTTGCGTAATGGCGATAC
AACAAAAGATGGGGTAGAGCTTGGTAAAAGTAATATCCTTCTGATTGGCCCAACGGGTAGTGGTAAAACATTACTTGCTG
AGACTCTAGCTCGTTTCTTGGATGTACCGTTTACTATGGCGGATGCAACCACATTAACTGAAGCGGGTTATGTTGGTGAA
GATGTTGAAAACATCATTCAAAAGCTATTACAAAAATGCGATTACGATCCTGCTAAAGCAGAGCGTGGCATTGTATATAT
CGATGAAATTGACAAGATTTCTCGTAAGTCTGAAAACCCATCAATTACACGTGATGTGTCTGGTGAAGGTGTTCAGCAAG
CGCTATTGAAATTGATTGAAGGCACAATTGCTTCAGTTCCACCTCAAGGTGGTCGTAAGCATCCACAGCAAGAATTCCTA
CAAGTAGATACATCTAAGATTCTATTTATTTGTGGTGGTGCTTTTGCTGGCTTAGATAAAGTAATTGAGCAACGTGTTGC
AACAGGTACAGGCATTGGTTTTGGTGCTGATGTTCGTTCTAAAGAAAACGAAGCAACAATCGGTGATTTGTTCAAGCAGA
TTGAACCAGAAGATTTAGTTAAGTTTGGTTTAATTCCAGAATTTATTGGCCGTTTACCTGTAACAACAACGCTGACTGAA
TTAGATGAAGAAGCGTTAGTTCAGATTTTAAGTCAACCTAAAAATGCATTAACGAAACAATATGGTGCATTATTTGATTT
AGAAGGTGCAGAGCTTGAATTCCGTGAAGATGCTTTAAAAGCAATTGCTAAAAAAGCAATGGATCGTAAAACAGGTGCTC
GTGGACTTCGTTCAATTCTAGAAGCGGTATTACTCGAGACTATGTATGAATTACCTTCAAAAGAAGGCGTTTCTAAAGTA
GTAATCGATGAGTCTGTGATTAATGGTGAATCAGAACCACTATTAATTTTTGAAAACACAGAAACAAAAGCAATTTCTGC
TGAATAG

Upstream 100 bases:

>100_bases
ATAAGCGTGACTAATTCATAAAAAAGCAGTAACGTTTACAGCAAAGAAGGTAAGTTAGTATAAACTTACAGCATAAAGGC
AACGTTTAAGAGGTTAGCAA

Downstream 100 bases:

>100_bases
CAAAAGACAAGTTAGTTGAATAAAAAGGAGGCATTGGCCTCCTTTTTTATTTTTTAATGAAAATTATATTGAATCTTAGC
GACTTGCCCCCATATTATTC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTDKRKDENSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVDLCNDIIREELKDNTLSPKESSEELPTPRNIREHLDDY
VIGQEHAKKVLAVAVYNHYKRLRNGDTTKDGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGE
DVENIIQKLLQKCDYDPAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFL
QVDTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKENEATIGDLFKQIEPEDLVKFGLIPEFIGRLPVTTTLTE
LDEEALVQILSQPKNALTKQYGALFDLEGAELEFREDALKAIAKKAMDRKTGARGLRSILEAVLLETMYELPSKEGVSKV
VIDESVINGESEPLLIFENTETKAISAE

Sequences:

>Translated_428_residues
MTDKRKDENSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVDLCNDIIREELKDNTLSPKESSEELPTPRNIREHLDDY
VIGQEHAKKVLAVAVYNHYKRLRNGDTTKDGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGE
DVENIIQKLLQKCDYDPAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFL
QVDTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKENEATIGDLFKQIEPEDLVKFGLIPEFIGRLPVTTTLTE
LDEEALVQILSQPKNALTKQYGALFDLEGAELEFREDALKAIAKKAMDRKTGARGLRSILEAVLLETMYELPSKEGVSKV
VIDESVINGESEPLLIFENTETKAISAE
>Mature_427_residues
TDKRKDENSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVDLCNDIIREELKDNTLSPKESSEELPTPRNIREHLDDYV
IGQEHAKKVLAVAVYNHYKRLRNGDTTKDGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGED
VENIIQKLLQKCDYDPAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFLQ
VDTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKENEATIGDLFKQIEPEDLVKFGLIPEFIGRLPVTTTLTEL
DEEALVQILSQPKNALTKQYGALFDLEGAELEFREDALKAIAKKAMDRKTGARGLRSILEAVLLETMYELPSKEGVSKVV
IDESVINGESEPLLIFENTETKAISAE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=333, Percent_Identity=51.0510510510511, Blast_Score=314, Evalue=1e-85,
Organism=Escherichia coli, GI1786642, Length=428, Percent_Identity=81.3084112149533, Blast_Score=706, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=101, Percent_Identity=43.5643564356436, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=313, Percent_Identity=44.7284345047923, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI71982905, Length=313, Percent_Identity=44.7284345047923, Blast_Score=260, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=392, Percent_Identity=37.5, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=40.1606425702811, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=429, Percent_Identity=39.1608391608392, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24648291, Length=324, Percent_Identity=45.3703703703704, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24648289, Length=324, Percent_Identity=45.3703703703704, Blast_Score=277, Evalue=8e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_VIBF1 (Q5E6Q4)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_204180.1
- HSSP:   P0A6H1
- ProteinModelPortal:   Q5E6Q4
- STRING:   Q5E6Q4
- GeneID:   3277446
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0797
- NMPDR:   fig|312309.3.peg.570
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q5E6Q4
- ProtClustDB:   PRK05342
- BioCyc:   VFIS312309:VF0797-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 47075; Mature: 46944

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRKDENSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVDLCNDIIREELKDNTLSP
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCC
KESSEELPTPRNIREHLDDYVIGQEHAKKVLAVAVYNHYKRLRNGDTTKDGVELGKSNIL
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEE
LIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDPAKA
EEECCCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
ERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFL
CCCEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
QVDTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKENEATIGDLFKQIEPEDLV
HHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHH
KFGLIPEFIGRLPVTTTLTELDEEALVQILSQPKNALTKQYGALFDLEGAELEFREDALK
HHCCHHHHHCCCCCHHHHHHCCHHHHHHHHHCHHHHHHHHHCCEEECCCCCHHHHHHHHH
AIAKKAMDRKTGARGLRSILEAVLLETMYELPSKEGVSKVVIDESVINGESEPLLIFENT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEHHHHHCCCCCCEEEEECC
ETKAISAE
CCCCCCCC
>Mature Secondary Structure 
TDKRKDENSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVDLCNDIIREELKDNTLSP
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCC
KESSEELPTPRNIREHLDDYVIGQEHAKKVLAVAVYNHYKRLRNGDTTKDGVELGKSNIL
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEE
LIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDPAKA
EEECCCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
ERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFL
CCCEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
QVDTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKENEATIGDLFKQIEPEDLV
HHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHH
KFGLIPEFIGRLPVTTTLTELDEEALVQILSQPKNALTKQYGALFDLEGAELEFREDALK
HHCCHHHHHCCCCCHHHHHHCCHHHHHHHHHCHHHHHHHHHCCEEECCCCCHHHHHHHHH
AIAKKAMDRKTGARGLRSILEAVLLETMYELPSKEGVSKVVIDESVINGESEPLLIFENT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEHHHHHCCCCCCEEEEECC
ETKAISAE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA