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The map label for this gene is dinB [H]

Identifier: 59711341

GI number: 59711341

Start: 799124

End: 800221

Strand: Direct

Name: dinB [H]

Synonym: VF_0734

Alternate gene names: 59711341

Gene position: 799124-800221 (Clockwise)

Preceding gene: 59711340

Following gene: 59711342

Centisome position: 27.58

GC content: 36.7

Gene sequence:

>1098_bases
ATGAGTATCGACCACCAATCATCTTCTTCGAAGCAAGTAACTAGAAATCAAAAGATTATTCATATTGATATGGATTGCTT
CTATGCGGCTGTTGAAATGCGAGATAATCCCAGTTTACGCAATGTACCTTTGGCGGTTGGGGGGCATGAACGTCAACGAG
GTGTACTAAGTACTTGTAATTATGAAGCTAGGAAGTTTGGTATTCGTTCTGCTATGCCAACAGGTAAAGCATTAAAATTA
TGCCCAAATCTCGTTGTTGTACCGGGCCGAATGCAGGTCTATAAAGAAGTATCTCACCATATTCATCGTATATTTCGACG
ATATACCGATAAAATTGAACCCCTCTCATTAGATGAAGCGTATTTAGATGTTAGTGATTGCTCACTTTTACACGGTTCTG
CAACATTAATTGCAGAGCAAATCAGAAAAGATATATTTAATGAGCTTCAGCTTACCGCTTCTGCTGGAATCGCCCCACTT
AAATTCTTAGCTAAAATTGCATCAGATCTTAATAAACCAAATGGACAGTATGTTATTACCCCTGATTCCATGATGAATGA
AATTAAGGGGTTACCTCTAGAGAAAATTCCTGGAGTAGGAAAAGTGAGTTTGGAGCGTCTTCATCAATTTGGGCTGTATA
CTTGTGAAGATATACAAAAGAGTGATCAAAGAGATTTATTACTGAAATTTGGGAAGATGGGAGCGTCATTATGGAAAAGA
TCTCATGGTATTGATGAAAGAGAGGTTGTCACTGAACGAAACCGAAAATCTGTGGGAGTAGAGCGGACATTTACACATAA
TATCAGTAGTTTTAATGAATGCTGGGATGTTATCGAAAATAGGTTATTTCCTGAGTTAGAAAAAAGGTTATTAAAAGCGA
ATGGTTCAACTTTTATTGCCAAGCAAGGGATTAAAATTAAGTTTGCTGACTTTCAACAAACGACAATTGAACATGTACAT
CATAACTTAACGCTACCATTTTTTAAGGAGCTGTTAGAAGAGGTGTTAGAAAGGCAAAAGGGAAGAGAGATTCGTTTAAT
TGGATTAAGTGTTACGCTCAAAGAGAAAGAGTATTTTCAACAATTACAACTCATTTAA

Upstream 100 bases:

>100_bases
AATTCCATTTTTAAACAGCACCTATTATTGGTGCTGTTTTTATTTGAATAAAAAATGGTTCAAAGTTATCATTAACTGTG
TTTTTATACAGTTAATTTTT

Downstream 100 bases:

>100_bases
TGATGAATAATATAATTTAGCGCTTCAATATTGAGATTTTAGTATAAATTTCATTTAAATTTATTGATTTTTGATTAAAG
ATAAAACAGTTGATTCTTAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSIDHQSSSSKQVTRNQKIIHIDMDCFYAAVEMRDNPSLRNVPLAVGGHERQRGVLSTCNYEARKFGIRSAMPTGKALKL
CPNLVVVPGRMQVYKEVSHHIHRIFRRYTDKIEPLSLDEAYLDVSDCSLLHGSATLIAEQIRKDIFNELQLTASAGIAPL
KFLAKIASDLNKPNGQYVITPDSMMNEIKGLPLEKIPGVGKVSLERLHQFGLYTCEDIQKSDQRDLLLKFGKMGASLWKR
SHGIDEREVVTERNRKSVGVERTFTHNISSFNECWDVIENRLFPELEKRLLKANGSTFIAKQGIKIKFADFQQTTIEHVH
HNLTLPFFKELLEEVLERQKGREIRLIGLSVTLKEKEYFQQLQLI

Sequences:

>Translated_365_residues
MSIDHQSSSSKQVTRNQKIIHIDMDCFYAAVEMRDNPSLRNVPLAVGGHERQRGVLSTCNYEARKFGIRSAMPTGKALKL
CPNLVVVPGRMQVYKEVSHHIHRIFRRYTDKIEPLSLDEAYLDVSDCSLLHGSATLIAEQIRKDIFNELQLTASAGIAPL
KFLAKIASDLNKPNGQYVITPDSMMNEIKGLPLEKIPGVGKVSLERLHQFGLYTCEDIQKSDQRDLLLKFGKMGASLWKR
SHGIDEREVVTERNRKSVGVERTFTHNISSFNECWDVIENRLFPELEKRLLKANGSTFIAKQGIKIKFADFQQTTIEHVH
HNLTLPFFKELLEEVLERQKGREIRLIGLSVTLKEKEYFQQLQLI
>Mature_364_residues
SIDHQSSSSKQVTRNQKIIHIDMDCFYAAVEMRDNPSLRNVPLAVGGHERQRGVLSTCNYEARKFGIRSAMPTGKALKLC
PNLVVVPGRMQVYKEVSHHIHRIFRRYTDKIEPLSLDEAYLDVSDCSLLHGSATLIAEQIRKDIFNELQLTASAGIAPLK
FLAKIASDLNKPNGQYVITPDSMMNEIKGLPLEKIPGVGKVSLERLHQFGLYTCEDIQKSDQRDLLLKFGKMGASLWKRS
HGIDEREVVTERNRKSVGVERTFTHNISSFNECWDVIENRLFPELEKRLLKANGSTFIAKQGIKIKFADFQQTTIEHVHH
NLTLPFFKELLEEVLERQKGREIRLIGLSVTLKEKEYFQQLQLI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=299, Percent_Identity=30.1003344481605, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI7706681, Length=300, Percent_Identity=30, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI154350220, Length=302, Percent_Identity=30.4635761589404, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=50.4672897196262, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI5729982, Length=346, Percent_Identity=27.7456647398844, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=61.3180515759312, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1787432, Length=214, Percent_Identity=26.1682242990654, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193205700, Length=406, Percent_Identity=32.2660098522167, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17537959, Length=297, Percent_Identity=27.6094276094276, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193205702, Length=343, Percent_Identity=27.9883381924198, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115534089, Length=117, Percent_Identity=41.025641025641, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=32.0388349514563, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19923006, Length=355, Percent_Identity=28.4507042253521, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI21355641, Length=299, Percent_Identity=29.0969899665552, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24644984, Length=299, Percent_Identity=29.0969899665552, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24668444, Length=116, Percent_Identity=34.4827586206897, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41727; Mature: 41596

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDHQSSSSKQVTRNQKIIHIDMDCFYAAVEMRDNPSLRNVPLAVGGHERQRGVLSTCN
CCCCCCCCCCHHHHCCCEEEEEEHHHHHHHHEECCCCCCCCCCEEECCCHHHCCHHHHCC
YEARKFGIRSAMPTGKALKLCPNLVVVPGRMQVYKEVSHHIHRIFRRYTDKIEPLSLDEA
HHHHHHHHHHCCCCCCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
YLDVSDCSLLHGSATLIAEQIRKDIFNELQLTASAGIAPLKFLAKIASDLNKPNGQYVIT
HCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEC
PDSMMNEIKGLPLEKIPGVGKVSLERLHQFGLYTCEDIQKSDQRDLLLKFGKMGASLWKR
CHHHHHHHCCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
SHGIDEREVVTERNRKSVGVERTFTHNISSFNECWDVIENRLFPELEKRLLKANGSTFIA
HCCCCHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEE
KQGIKIKFADFQQTTIEHVHHNLTLPFFKELLEEVLERQKGREIRLIGLSVTLKEKEYFQ
ECCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECHHHHHH
QLQLI
HHCCC
>Mature Secondary Structure 
SIDHQSSSSKQVTRNQKIIHIDMDCFYAAVEMRDNPSLRNVPLAVGGHERQRGVLSTCN
CCCCCCCCCHHHHCCCEEEEEEHHHHHHHHEECCCCCCCCCCEEECCCHHHCCHHHHCC
YEARKFGIRSAMPTGKALKLCPNLVVVPGRMQVYKEVSHHIHRIFRRYTDKIEPLSLDEA
HHHHHHHHHHCCCCCCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
YLDVSDCSLLHGSATLIAEQIRKDIFNELQLTASAGIAPLKFLAKIASDLNKPNGQYVIT
HCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEC
PDSMMNEIKGLPLEKIPGVGKVSLERLHQFGLYTCEDIQKSDQRDLLLKFGKMGASLWKR
CHHHHHHHCCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
SHGIDEREVVTERNRKSVGVERTFTHNISSFNECWDVIENRLFPELEKRLLKANGSTFIA
HCCCCHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEE
KQGIKIKFADFQQTTIEHVHHNLTLPFFKELLEEVLERQKGREIRLIGLSVTLKEKEYFQ
ECCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECHHHHHH
QLQLI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA