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The map label for this gene is apbE [H]

Identifier: 59711339

GI number: 59711339

Start: 797732

End: 798766

Strand: Direct

Name: apbE [H]

Synonym: VF_0732

Alternate gene names: 59711339

Gene position: 797732-798766 (Clockwise)

Preceding gene: 59711338

Following gene: 59711340

Centisome position: 27.53

GC content: 38.55

Gene sequence:

>1035_bases
GTGTTTGTCAGTTTTACTCAGTTAATTAATAAAGCAAAACTTATTTTATTACCTTGTTTTGCCCTTATTTTACTTGCTGG
TTGTGGTGATCAGCGTGAGCAAGTCTATCTGAATGGTCCTACGATGGGGACAAGCTATAATATTAAATATATAAGCAAAG
ATGGACTGCCTAAATCTGAAGACGTTCATGCGGAGATAGATAAGCGATTAGAGCTTGTTAATGACCAAATGTCGACATAC
AGAAAAGATTCAGAGTTGAGTCGATTTAACCAAAGTAAAGAACTGACTCCATTTACAGTATCAAAAGATACGGCAACCGT
TATTAAAGAAGCGATTCGATTGAATAAGGTTACTTTAGGAGCGCTTGATGTAACTGTTGGTCCTCTTGTTAATCTATGGG
GATTTGGACCAGAAGCTCGACCAGAAGTCGTTCCTACTGATGAAGAATTAAATGCGCGACGTAAAATTGTTGGCATTCAG
CATTTAGAAGCAACAGAAACTACAGTTACAAAAGATATCCCTGAGCTATATGTTGATTTATCAACGATCGCTAAAGGTTG
GGGTGTTGACGTTGTTGCTAATTACCTAGAAGAGCTTGGCATCACTGATTACATGGTTGAAGTCGGTGGTGAGATGCGAG
TGAAAGGCAAAAATAAAGAAAATGTTGCTTGGCGTATCGCAATTGAAAAACCATCAGTTGATGAGCGTGCGATTCAAGAG
ATTATAGAGCCGGGTCATCATGCAGTAGCGACATCTGGCGATTACCGTATATACTTTGAGAAAGAGGGTATCCGTTACTC
TCATATTATTAACCCAATTACAGGTTACCCTATTTCAAATAAGGTAGTATCTGTAACGGTACTCGATAAATCATCAATGA
CGGCCGATGGACTTGCTACGGGTTTAATGCTTCTTGGTGAAGAGCAAGGTATAGAGGTTGCTAATAAACACAATATTCCT
GTTTTCATGATAGTGAAAACGAAAGATGGCTTTAAAGAGATAGCATCTGAAGCCTTTAAGCCTTTTTTGAAGTAA

Upstream 100 bases:

>100_bases
TATGGTCCGTATTTAACCTGACAAAGTACAGGGTTATAGGTTTAGTAAACAAACTTAAATTTATATTCCTGTGTATTGTT
TGTATTTAAAGGAGTTGGCA

Downstream 100 bases:

>100_bases
GTGAGTAAATAATGAATACATTTCTGATTACATTTTTTGTTTTCTTAGCGGTAATTGCTGCAATGGCTATTGGTTACATT
ATTCAGCGTAAAGTTGTAAA

Product: thiamine biosynthesis lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MFVSFTQLINKAKLILLPCFALILLAGCGDQREQVYLNGPTMGTSYNIKYISKDGLPKSEDVHAEIDKRLELVNDQMSTY
RKDSELSRFNQSKELTPFTVSKDTATVIKEAIRLNKVTLGALDVTVGPLVNLWGFGPEARPEVVPTDEELNARRKIVGIQ
HLEATETTVTKDIPELYVDLSTIAKGWGVDVVANYLEELGITDYMVEVGGEMRVKGKNKENVAWRIAIEKPSVDERAIQE
IIEPGHHAVATSGDYRIYFEKEGIRYSHIINPITGYPISNKVVSVTVLDKSSMTADGLATGLMLLGEEQGIEVANKHNIP
VFMIVKTKDGFKEIASEAFKPFLK

Sequences:

>Translated_344_residues
MFVSFTQLINKAKLILLPCFALILLAGCGDQREQVYLNGPTMGTSYNIKYISKDGLPKSEDVHAEIDKRLELVNDQMSTY
RKDSELSRFNQSKELTPFTVSKDTATVIKEAIRLNKVTLGALDVTVGPLVNLWGFGPEARPEVVPTDEELNARRKIVGIQ
HLEATETTVTKDIPELYVDLSTIAKGWGVDVVANYLEELGITDYMVEVGGEMRVKGKNKENVAWRIAIEKPSVDERAIQE
IIEPGHHAVATSGDYRIYFEKEGIRYSHIINPITGYPISNKVVSVTVLDKSSMTADGLATGLMLLGEEQGIEVANKHNIP
VFMIVKTKDGFKEIASEAFKPFLK
>Mature_344_residues
MFVSFTQLINKAKLILLPCFALILLAGCGDQREQVYLNGPTMGTSYNIKYISKDGLPKSEDVHAEIDKRLELVNDQMSTY
RKDSELSRFNQSKELTPFTVSKDTATVIKEAIRLNKVTLGALDVTVGPLVNLWGFGPEARPEVVPTDEELNARRKIVGIQ
HLEATETTVTKDIPELYVDLSTIAKGWGVDVVANYLEELGITDYMVEVGGEMRVKGKNKENVAWRIAIEKPSVDERAIQE
IIEPGHHAVATSGDYRIYFEKEGIRYSHIINPITGYPISNKVVSVTVLDKSSMTADGLATGLMLLGEEQGIEVANKHNIP
VFMIVKTKDGFKEIASEAFKPFLK

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=356, Percent_Identity=40.4494382022472, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 38218; Mature: 38218

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVSFTQLINKAKLILLPCFALILLAGCGDQREQVYLNGPTMGTSYNIKYISKDGLPKSE
CEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCCC
DVHAEIDKRLELVNDQMSTYRKDSELSRFNQSKELTPFTVSKDTATVIKEAIRLNKVTLG
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHCCEEEE
ALDVTVGPLVNLWGFGPEARPEVVPTDEELNARRKIVGIQHLEATETTVTKDIPELYVDL
EEHEEHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHEEEHECCCCCHHHHHHHHHHHHHHH
STIAKGWGVDVVANYLEELGITDYMVEVGGEMRVKGKNKENVAWRIAIEKPSVDERAIQE
HHHHCCCCHHHHHHHHHHCCCHHEEECCCCEEEECCCCCCCEEEEEEEECCCCCHHHHHH
IIEPGHHAVATSGDYRIYFEKEGIRYSHIINPITGYPISNKVVSVTVLDKSSMTADGLAT
HHCCCCCEEEECCCEEEEEECCCCEEHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
GLMLLGEEQGIEVANKHNIPVFMIVKTKDGFKEIASEAFKPFLK
HHHEECCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFVSFTQLINKAKLILLPCFALILLAGCGDQREQVYLNGPTMGTSYNIKYISKDGLPKSE
CEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCCC
DVHAEIDKRLELVNDQMSTYRKDSELSRFNQSKELTPFTVSKDTATVIKEAIRLNKVTLG
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHCCEEEE
ALDVTVGPLVNLWGFGPEARPEVVPTDEELNARRKIVGIQHLEATETTVTKDIPELYVDL
EEHEEHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHEEEHECCCCCHHHHHHHHHHHHHHH
STIAKGWGVDVVANYLEELGITDYMVEVGGEMRVKGKNKENVAWRIAIEKPSVDERAIQE
HHHHCCCCHHHHHHHHHHCCCHHEEECCCCEEEECCCCCCCEEEEEEEECCCCCHHHHHH
IIEPGHHAVATSGDYRIYFEKEGIRYSHIINPITGYPISNKVVSVTVLDKSSMTADGLAT
HHCCCCCEEEECCCEEEEEECCCCEEHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
GLMLLGEEQGIEVANKHNIPVFMIVKTKDGFKEIASEAFKPFLK
HHHEECCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]