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The map label for this gene is ywbA [H]

Identifier: 59711210

GI number: 59711210

Start: 662465

End: 663820

Strand: Direct

Name: ywbA [H]

Synonym: VF_0603

Alternate gene names: 59711210

Gene position: 662465-663820 (Clockwise)

Preceding gene: 59711207

Following gene: 59711211

Centisome position: 22.86

GC content: 38.5

Gene sequence:

>1356_bases
ATGGGTACTCAAGCGGTAAATTTGCAAAGTACTATCATGGAAAAGGTGAATAAATTCCTACCTAAAATTTTAAAGGTTGT
GAATTCAAAACCGATCGTAGCGATTAAAGAAGGCTTCATGTTAACAATGCCATTGACCATTATAGGTTCAGTGTTTTTGT
TATTGGCGTTTGTACCTATTGATGGTTACAACGAGTTTATGGCTGGAATTTTTGGAGCAGAATGGTCAACACCATTGTTT
CAAGTTGTAGGGGCAACATTTGATATTTTGGCACTAATTGGTGCTTTTGGTATTGCGTATACTTACGTTAAATATGAAGG
ACATAATGGTGTAAATGCGGGGGTATTAGCCATTGTTTCTCTTCTTATTGTAATGAATGCCTTTGTTGTCGCACCTGATG
GTGTAACTCAAATTGGTGGCGTAATACCGAAAGCCTTTCTTGGTGGTAAAGGTATGATCGCAGCAATCGTGATTGGTTTA
GTTGTTGGTATTATTTATTCAATGGCCTTTAATCGTAATTGGGTTATCAAACTACCTGATAGTGTGCCTGAAGGGGTATC
CAATGCATTTAAATCGCTTATTCCTGGTTTTCTTATTATCACTCTTGCTTTCTTAACGTATATCTTCTTTGAAGTTGTAT
TTGAAAGAACCTTTATTGAAACCATTTATCATATTATTCAAACACCACTACAAAGCATGTCTGATTCATTCTTTGGAGCG
GTTGGTATTGCTTTGCTTATTTCTCTGCTTTGGTGGTGTGGTGTTCATGGTCCAGTTATTGTTATGGGCATCATGGGACC
AATCGTGACTGCGAACGCACTTCATAATCAATCTATCGTTAATGCAGGCGAAGCATTGATTGCTGGCGAAAATGGCAAAG
TGGTAACTAACCAGTTTGTTGACCAATTCATTACTGTTGGCGGTTCAGGTCTAACGTTTGGTTTAGTGTGCTGTATGGTG
TTATTTGCTCGTTCTATTCAGTTCAAACAACTTGGTCGTCTTTCTTTTATCCCAGGTATTTTCAATATCAATGAACCTGT
GATTTTTGCAACTCCAATTATCTTTAACCCAATCATGTTTATTCCATTTGTAACAGCACCAGTGCTATCAGCAATTATGG
TTTATACGTCAATTAATATGGGATTTGTTGGTCCATTTACCGCAGTTCAAGTGCCTTGGACAACGCCTATGGTGCTTAGC
GGATTCATCGTTGGTGGTTGGAGTGCAGCATTACTACAAATAGCCGTGTTCTGTATGACAGTGTGCGTTTATTTCCCATT
CTTTAAATATCAAGACAAGTTAGCAGCTCAAGATGAAGCAAAGGCAGCAGCGCCAACATCACAAGCAACAGCTTAA

Upstream 100 bases:

>100_bases
ATTTGCTCAATTATGATATGTAACCGGTTACTGAAACCGGTTACATTTCTCCTCAGTGAATAAAAGTTAATAAATTTATA
ATTCTAATTAGGGGTGAACA

Downstream 100 bases:

>100_bases
TTAAAACAGATTAGATGAGTATCGAGGTTATTATGAAAAAGATTTTATTACTATGTGCAGCAGGTATGTCTACGTCAATG
GTTGTAAAAAAAATGCGTGA

Product: PTS system, cellobiose-utilization IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MGTQAVNLQSTIMEKVNKFLPKILKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPIDGYNEFMAGIFGAEWSTPLF
QVVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVSLLIVMNAFVVAPDGVTQIGGVIPKAFLGGKGMIAAIVIGL
VVGIIYSMAFNRNWVIKLPDSVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGA
VGIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEALIAGENGKVVTNQFVDQFITVGGSGLTFGLVCCMV
LFARSIQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMFIPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPMVLS
GFIVGGWSAALLQIAVFCMTVCVYFPFFKYQDKLAAQDEAKAAAPTSQATA

Sequences:

>Translated_451_residues
MGTQAVNLQSTIMEKVNKFLPKILKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPIDGYNEFMAGIFGAEWSTPLF
QVVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVSLLIVMNAFVVAPDGVTQIGGVIPKAFLGGKGMIAAIVIGL
VVGIIYSMAFNRNWVIKLPDSVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGA
VGIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEALIAGENGKVVTNQFVDQFITVGGSGLTFGLVCCMV
LFARSIQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMFIPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPMVLS
GFIVGGWSAALLQIAVFCMTVCVYFPFFKYQDKLAAQDEAKAAAPTSQATA
>Mature_450_residues
GTQAVNLQSTIMEKVNKFLPKILKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPIDGYNEFMAGIFGAEWSTPLFQ
VVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVSLLIVMNAFVVAPDGVTQIGGVIPKAFLGGKGMIAAIVIGLV
VGIIYSMAFNRNWVIKLPDSVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGAV
GIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEALIAGENGKVVTNQFVDQFITVGGSGLTFGLVCCMVL
FARSIQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMFIPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPMVLSG
FIVGGWSAALLQIAVFCMTVCVYFPFFKYQDKLAAQDEAKAAAPTSQATA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=457, Percent_Identity=32.6039387308534, Blast_Score=192, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 48466; Mature: 48335

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTQAVNLQSTIMEKVNKFLPKILKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPI
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECHHHHHHHHHHHHHHCC
DGYNEFMAGIFGAEWSTPLFQVVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVS
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHH
LLIVMNAFVVAPDGVTQIGGVIPKAFLGGKGMIAAIVIGLVVGIIYSMAFNRNWVIKLPD
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
SVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEALIAGENGKVVTNQFV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
DQFITVGGSGLTFGLVCCMVLFARSIQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMF
HHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCCCCEEEECHHHHHHHHH
IPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPMVLSGFIVGGWSAALLQIAVFCMT
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
VCVYFPFFKYQDKLAAQDEAKAAAPTSQATA
HHHHHHHHHHHHHHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
GTQAVNLQSTIMEKVNKFLPKILKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECHHHHHHHHHHHHHHCC
DGYNEFMAGIFGAEWSTPLFQVVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVS
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHH
LLIVMNAFVVAPDGVTQIGGVIPKAFLGGKGMIAAIVIGLVVGIIYSMAFNRNWVIKLPD
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
SVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEALIAGENGKVVTNQFV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
DQFITVGGSGLTFGLVCCMVLFARSIQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMF
HHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCCCCEEEECHHHHHHHHH
IPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPMVLSGFIVGGWSAALLQIAVFCMT
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
VCVYFPFFKYQDKLAAQDEAKAAAPTSQATA
HHHHHHHHHHHHHHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]