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The map label for this gene is aroF [H]

Identifier: 59711160

GI number: 59711160

Start: 600707

End: 601780

Strand: Direct

Name: aroF [H]

Synonym: VF_0553

Alternate gene names: 59711160

Gene position: 600707-601780 (Clockwise)

Preceding gene: 59711159

Following gene: 59711161

Centisome position: 20.73

GC content: 37.62

Gene sequence:

>1074_bases
ATGAGAAAAAGTGAATTAAGTAATATCAATATTATCGATGAGCAGGTGCTGATCACTCCACAAGAGCTTAAAAATAAGAT
CCCTTTAAGCGAAAATGCTCGCCAGTTTATCCAACAATCCCGTCAAACTATTTCTAATATCATTCATAAAAAAGATCACC
GTCTATTAATTGTTTGTGGACCATGTTCAATTCATGATATCGATGCAGCAAAAGAATATGCAAAACGTTTAAAGGTGATC
GCAGAAGATCTAAAAGATCAACTGTACATTGTTATGCGTGTCTACTTTGAAAAACCACGAACTACAGTAGGCTGGAAAGG
CTTGATTAATGATCCTCATCTTGATGGTTCATTTGATATTGAACAAGGTCTACATTCTGCACGACAATTATTAGTTGATT
TAGCTGAGATGGAAATCCCTCTGGCAACAGAAGCACTAGATCCAATTAGTCCGCAATACATTGGTGATACATTTAGTTGG
GCTGCGATTGGGGCTCGAACCACTGAATCTCAAACTCACCGTGAAATGGCAAGTGGTTTATCTGTTCCTGTAGGCTTTAA
AAATGGTACTGATGGCAGCTTATCGACATCGATTAATGCAATGCAAGCTGCGGCTTCTGGACACCGTTTCATGGGGATTA
ATAGCGAAGGTCAGGTTGCTTTACTTACAACCCAAGGTAACCCTAATGGTCATGTTATTTTACGTGGTGGTAAACAAACT
AATTATGATTCGGTTTCAGTAACAGAGTGTGAAGAAGAATTAGCAAATTCAAATTTAGATGCGGCTTTAATGATTGATTG
TAGTCACGCAAATTCACGCAAAGATTACCGTCGTCAGCCTTTAGTTGCTGAAGATGTTATTCATCAAATTCGTGAAGGTA
ATAAATCGATTATTGGATTGATGATTGAGAGTCATTTAAATGAAGGTAATCAACCATCAGATATACCATTGTCTGAGATG
AAATATGGCGTATCTATTACAGATGCCTGTATCAATTGGGAATCAACTGAGGCACTATTACGTCATACTCACAAAGAATT
AACTCCGATATTGGAAGAGCGTTTAAAAGGATAG

Upstream 100 bases:

>100_bases
ATATTAATTACAATGGTTGATTTATGTGCTGTACCTGTTAAATTATTTGTATTCGTCTTAATTGACAGTTAATGGAAATA
AAAGTTTACAGGTGTAGGGT

Downstream 100 bases:

>100_bases
ATTGAGATGGCGGTAGAACTAAGTCATTTACGCGATCAAATTGATGCGGTAGATAAACAGATGTTGGATCTTTTAGCTCA
ACGCTTACATTTAGTTGAGC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRKSELSNINIIDEQVLITPQELKNKIPLSENARQFIQQSRQTISNIIHKKDHRLLIVCGPCSIHDIDAAKEYAKRLKVI
AEDLKDQLYIVMRVYFEKPRTTVGWKGLINDPHLDGSFDIEQGLHSARQLLVDLAEMEIPLATEALDPISPQYIGDTFSW
AAIGARTTESQTHREMASGLSVPVGFKNGTDGSLSTSINAMQAAASGHRFMGINSEGQVALLTTQGNPNGHVILRGGKQT
NYDSVSVTECEEELANSNLDAALMIDCSHANSRKDYRRQPLVAEDVIHQIREGNKSIIGLMIESHLNEGNQPSDIPLSEM
KYGVSITDACINWESTEALLRHTHKELTPILEERLKG

Sequences:

>Translated_357_residues
MRKSELSNINIIDEQVLITPQELKNKIPLSENARQFIQQSRQTISNIIHKKDHRLLIVCGPCSIHDIDAAKEYAKRLKVI
AEDLKDQLYIVMRVYFEKPRTTVGWKGLINDPHLDGSFDIEQGLHSARQLLVDLAEMEIPLATEALDPISPQYIGDTFSW
AAIGARTTESQTHREMASGLSVPVGFKNGTDGSLSTSINAMQAAASGHRFMGINSEGQVALLTTQGNPNGHVILRGGKQT
NYDSVSVTECEEELANSNLDAALMIDCSHANSRKDYRRQPLVAEDVIHQIREGNKSIIGLMIESHLNEGNQPSDIPLSEM
KYGVSITDACINWESTEALLRHTHKELTPILEERLKG
>Mature_357_residues
MRKSELSNINIIDEQVLITPQELKNKIPLSENARQFIQQSRQTISNIIHKKDHRLLIVCGPCSIHDIDAAKEYAKRLKVI
AEDLKDQLYIVMRVYFEKPRTTVGWKGLINDPHLDGSFDIEQGLHSARQLLVDLAEMEIPLATEALDPISPQYIGDTFSW
AAIGARTTESQTHREMASGLSVPVGFKNGTDGSLSTSINAMQAAASGHRFMGINSEGQVALLTTQGNPNGHVILRGGKQT
NYDSVSVTECEEELANSNLDAALMIDCSHANSRKDYRRQPLVAEDVIHQIREGNKSIIGLMIESHLNEGNQPSDIPLSEM
KYGVSITDACINWESTEALLRHTHKELTPILEERLKG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=355, Percent_Identity=66.7605633802817, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1786969, Length=328, Percent_Identity=56.4024390243902, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1787996, Length=339, Percent_Identity=47.4926253687316, Blast_Score=328, Evalue=5e-91,
Organism=Saccharomyces cerevisiae, GI6319726, Length=339, Percent_Identity=53.9823008849557, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320240, Length=331, Percent_Identity=50.4531722054381, Blast_Score=338, Evalue=9e-94,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39654; Mature: 39654

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSELSNINIIDEQVLITPQELKNKIPLSENARQFIQQSRQTISNIIHKKDHRLLIVCG
CCCCCCCCCEEECCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PCSIHDIDAAKEYAKRLKVIAEDLKDQLYIVMRVYFEKPRTTVGWKGLINDPHLDGSFDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EQGLHSARQLLVDLAEMEIPLATEALDPISPQYIGDTFSWAAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHCCCCCCHHHCCCCCCHHHHHHHHHCCC
SVPVGFKNGTDGSLSTSINAMQAAASGHRFMGINSEGQVALLTTQGNPNGHVILRGGKQT
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCEEEEECCCCC
NYDSVSVTECEEELANSNLDAALMIDCSHANSRKDYRRQPLVAEDVIHQIREGNKSIIGL
CCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCCHHHHHHHHHHCCCCCEEHH
MIESHLNEGNQPSDIPLSEMKYGVSITDACINWESTEALLRHTHKELTPILEERLKG
HHHHHCCCCCCCCCCCHHHHHCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKSELSNINIIDEQVLITPQELKNKIPLSENARQFIQQSRQTISNIIHKKDHRLLIVCG
CCCCCCCCCEEECCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PCSIHDIDAAKEYAKRLKVIAEDLKDQLYIVMRVYFEKPRTTVGWKGLINDPHLDGSFDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EQGLHSARQLLVDLAEMEIPLATEALDPISPQYIGDTFSWAAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHCCCCCCHHHCCCCCCHHHHHHHHHCCC
SVPVGFKNGTDGSLSTSINAMQAAASGHRFMGINSEGQVALLTTQGNPNGHVILRGGKQT
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCEEEEECCCCC
NYDSVSVTECEEELANSNLDAALMIDCSHANSRKDYRRQPLVAEDVIHQIREGNKSIIGL
CCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCCHHHHHHHHHHCCCCCEEHH
MIESHLNEGNQPSDIPLSEMKYGVSITDACINWESTEALLRHTHKELTPILEERLKG
HHHHHCCCCCCCCCCCHHHHHCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]