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The map label for this gene is serB [H]

Identifier: 59711116

GI number: 59711116

Start: 546319

End: 547296

Strand: Direct

Name: serB [H]

Synonym: VF_0509

Alternate gene names: 59711116

Gene position: 546319-547296 (Clockwise)

Preceding gene: 59711114

Following gene: 59711117

Centisome position: 18.85

GC content: 38.55

Gene sequence:

>978_bases
ATGCAAATCATGGATAGGATAATCCCATTTTCAATTAAGAAACACATACCATTATTAAATCGTTTTAGCTCAACCTTAAC
AACGACGCAATTCGACGTTAAAAAAACAGGTTGGATTATTTACGGTCCTCAATTATCACCTCGTCATTTTGATGATATCG
ATTTTTTTGTCGGTTATAAAACGCAACTAATTAAAACTTGGAAAGTTGGTTATTACGAAGTTGCTGCTATAGCTGGTGCG
CTTACAGAAGAGCATAAAATTATCGTTGATGCGCTCGGTTTAGATTACGCAGAGATGAAAGATATTCCTGATCTATCAAA
ACCAGGGATCATTTTATTTGACATGGATTCAACGGCGATCGAAATCGAATGTATTGATGAAATAGCGAAATTAGCGGGTG
TTGGTGAGCAAGTTGCAGAAGTAACAGAAAGAGCAATGCAAGGTGAACTGGATTTTAAAGAGAGTTTAATTCAGCGTGTA
GGAACTCTGGCAGGAGCTGATGAAGCTATTCTTGCTGAAGTAAAAGCAAACTTACCTTTTATGCCTGAAATCAGAGAGCT
AGTTGCTACCATGCATAAATACGGTTGGAAACCGGCTATTGCCTCGGGTGGTTTCACTTATTTTTCTGATTATTTAAAAC
AAGAACTCAATCTTGTACATGCACAATCGAATCAGCTAGAGATTGTTGATGGCAAACTTACCGGTAAGGTTCTTGGTGAA
ATTGTCAGTGCAGAGACGAAGGCACATATTTTAGTTGAGCTTGCTGATAAATATGACATAGAGATCAGCAATACGGTTGC
CGTTGGTGATGGTGCTAATGATCTGGTTATGATGGAAGCGGCAGGCCTTGGTATTGCCTATCACGCAAAACCTAAAGTAC
AAGAGCAAGCACAAACCGCAATTAAACATGCAGATTTAGGTGGTGTTGCTTGTATTTTATCTGCTTCGTTATTGTTTGGT
AATAAACTGAGTTGGTAG

Upstream 100 bases:

>100_bases
GCAGTAATTATACTGAATTTATCGAAAAAAAGCAGTTTATGTCATTTGCCTCTTGCTCAACTCCTCTTCAATCGGTATTT
TTTAGACAGGACAAGAAAGG

Downstream 100 bases:

>100_bases
AAGCTTAATCTTCCATAAGTTTAATATAAATAATGAGCTTTATTATAAAGCTCATTTTTTTGCGTTAAATTCAGCAATAA
CGGTTACATATTACGTGAAT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MQIMDRIIPFSIKKHIPLLNRFSSTLTTTQFDVKKTGWIIYGPQLSPRHFDDIDFFVGYKTQLIKTWKVGYYEVAAIAGA
LTEEHKIIVDALGLDYAEMKDIPDLSKPGIILFDMDSTAIEIECIDEIAKLAGVGEQVAEVTERAMQGELDFKESLIQRV
GTLAGADEAILAEVKANLPFMPEIRELVATMHKYGWKPAIASGGFTYFSDYLKQELNLVHAQSNQLEIVDGKLTGKVLGE
IVSAETKAHILVELADKYDIEISNTVAVGDGANDLVMMEAAGLGIAYHAKPKVQEQAQTAIKHADLGGVACILSASLLFG
NKLSW

Sequences:

>Translated_325_residues
MQIMDRIIPFSIKKHIPLLNRFSSTLTTTQFDVKKTGWIIYGPQLSPRHFDDIDFFVGYKTQLIKTWKVGYYEVAAIAGA
LTEEHKIIVDALGLDYAEMKDIPDLSKPGIILFDMDSTAIEIECIDEIAKLAGVGEQVAEVTERAMQGELDFKESLIQRV
GTLAGADEAILAEVKANLPFMPEIRELVATMHKYGWKPAIASGGFTYFSDYLKQELNLVHAQSNQLEIVDGKLTGKVLGE
IVSAETKAHILVELADKYDIEISNTVAVGDGANDLVMMEAAGLGIAYHAKPKVQEQAQTAIKHADLGGVACILSASLLFG
NKLSW
>Mature_325_residues
MQIMDRIIPFSIKKHIPLLNRFSSTLTTTQFDVKKTGWIIYGPQLSPRHFDDIDFFVGYKTQLIKTWKVGYYEVAAIAGA
LTEEHKIIVDALGLDYAEMKDIPDLSKPGIILFDMDSTAIEIECIDEIAKLAGVGEQVAEVTERAMQGELDFKESLIQRV
GTLAGADEAILAEVKANLPFMPEIRELVATMHKYGWKPAIASGGFTYFSDYLKQELNLVHAQSNQLEIVDGKLTGKVLGE
IVSAETKAHILVELADKYDIEISNTVAVGDGANDLVMMEAAGLGIAYHAKPKVQEQAQTAIKHADLGGVACILSASLLFG
NKLSW

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=170, Percent_Identity=30, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790849, Length=287, Percent_Identity=53.3101045296167, Blast_Score=308, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI115534454, Length=178, Percent_Identity=32.0224719101124, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=178, Percent_Identity=32.0224719101124, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=44.6601941747573, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35689; Mature: 35689

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIMDRIIPFSIKKHIPLLNRFSSTLTTTQFDVKKTGWIIYGPQLSPRHFDDIDFFVGYK
CCHHHHHCCHHHHHCCHHHHHHHHHHEEEEEEEECCCEEEECCCCCCCCCCCCCEEECCH
TQLIKTWKVGYYEVAAIAGALTEEHKIIVDALGLDYAEMKDIPDLSKPGIILFDMDSTAI
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCCCCCEEEEECCCCEE
EIECIDEIAKLAGVGEQVAEVTERAMQGELDFKESLIQRVGTLAGADEAILAEVKANLPF
EHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
MPEIRELVATMHKYGWKPAIASGGFTYFSDYLKQELNLVHAQSNQLEIVDGKLTGKVLGE
CHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
IVSAETKAHILVELADKYDIEISNTVAVGDGANDLVMMEAAGLGIAYHAKPKVQEQAQTA
HHHCCCHHEEEEEECCCCCEEECCEEEECCCCCCEEEEEECCCCEEECCCCCHHHHHHHH
IKHADLGGVACILSASLLFGNKLSW
HHHCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQIMDRIIPFSIKKHIPLLNRFSSTLTTTQFDVKKTGWIIYGPQLSPRHFDDIDFFVGYK
CCHHHHHCCHHHHHCCHHHHHHHHHHEEEEEEEECCCEEEECCCCCCCCCCCCCEEECCH
TQLIKTWKVGYYEVAAIAGALTEEHKIIVDALGLDYAEMKDIPDLSKPGIILFDMDSTAI
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCCCCCEEEEECCCCEE
EIECIDEIAKLAGVGEQVAEVTERAMQGELDFKESLIQRVGTLAGADEAILAEVKANLPF
EHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
MPEIRELVATMHKYGWKPAIASGGFTYFSDYLKQELNLVHAQSNQLEIVDGKLTGKVLGE
CHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
IVSAETKAHILVELADKYDIEISNTVAVGDGANDLVMMEAAGLGIAYHAKPKVQEQAQTA
HHHCCCHHEEEEEECCCCCEEECCEEEECCCCCCEEEEEECCCCEEECCCCCHHHHHHHH
IKHADLGGVACILSASLLFGNKLSW
HHHCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]