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The map label for this gene is deoC [H]

Identifier: 59711111

GI number: 59711111

Start: 541279

End: 542055

Strand: Direct

Name: deoC [H]

Synonym: VF_0504

Alternate gene names: 59711111

Gene position: 541279-542055 (Clockwise)

Preceding gene: 59711110

Following gene: 59711112

Centisome position: 18.68

GC content: 40.15

Gene sequence:

>777_bases
ATGAGCGATTTAAAAGCAGCTGCACTACGTGCATTAAAGTTGATGGATTTAACAACACTAAACGATAACGATACAGACGA
AGCGGTAATTGCACTTTGTAAAAATGCAAAAACAGCAGTAGGTAATACAGCAGCTGTATGTATCTACCCTCGTTTTATTC
CTATCGCTAAGAAAACGCTGCGCGAACAAGGCACACCAGAAGTACGCATTGCAACAGTAACTAACTTCCCTCACGGTAAT
GATGATATTGAGATTGCTGTTGCTGAAACAAAAGCAGCGGTTGCTTATGGTGCAGATGAAGTTGATGTGGTTTTCCCATA
TCGTGCTCTTATTGCTGGTGATGAAACAACAGGTTTTGAACTAGTTAAGCAATGTAAAGAAGCATGTGGTGATGTTCTTC
TTAAAGTAATCATCGAAACTGGTGAATTAAAAGAAGAAGCATTAATCAAAAAAGCATCTCAAATCTGTATTGAAGCTGGT
GCTAACTTTATTAAAACCTCAACAGGTAAAGTGCCAGTAAATGCTACACCTGAATATGCTCGTATGATGCTTGAAGTTAT
CCGTGATATGGATGTAGCTAAAACAGTTGGTTTTAAACCTGCTGGCGGCGTTCGTACTGCTGAAGATGCACAAGCATACC
TAGCGATGGCTGATGATATTCTTGGTGGCGATTGGGCTGATAACATGCACTACCGTTTTGGTGCATCAAGCCTACTGACT
AACCTATTAAATACATTAGAGGTAACAGAAGAAACGGCTGATCCATCAGCTTACTAG

Upstream 100 bases:

>100_bases
TTGCCCAATTCTTCAAGGAATCAAGTCCGCTCATTTGCTGTTGAACGTACTTAACCTGAACAGCAAAACTATCAAAGAAT
TCTATCTATCGGAGATAACA

Downstream 100 bases:

>100_bases
TTTCTCGTTACTTGATTTATAGCTAAGAAATAAATCGACTTAGGTGAGACATACTCGTCTCACCTACCTCAACCCTACCT
ATTTTAATTACCCAACCAAG

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFIPIAKKTLREQGTPEVRIATVTNFPHGN
DDIEIAVAETKAAVAYGADEVDVVFPYRALIAGDETTGFELVKQCKEACGDVLLKVIIETGELKEEALIKKASQICIEAG
ANFIKTSTGKVPVNATPEYARMMLEVIRDMDVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLT
NLLNTLEVTEETADPSAY

Sequences:

>Translated_258_residues
MSDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFIPIAKKTLREQGTPEVRIATVTNFPHGN
DDIEIAVAETKAAVAYGADEVDVVFPYRALIAGDETTGFELVKQCKEACGDVLLKVIIETGELKEEALIKKASQICIEAG
ANFIKTSTGKVPVNATPEYARMMLEVIRDMDVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLT
NLLNTLEVTEETADPSAY
>Mature_257_residues
SDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFIPIAKKTLREQGTPEVRIATVTNFPHGND
DIEIAVAETKAAVAYGADEVDVVFPYRALIAGDETTGFELVKQCKEACGDVLLKVIIETGELKEEALIKKASQICIEAGA
NFIKTSTGKVPVNATPEYARMMLEVIRDMDVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLTN
LLNTLEVTEETADPSAY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116063554, Length=254, Percent_Identity=37.7952755905512, Blast_Score=158, Evalue=5e-39,
Organism=Escherichia coli, GI1790841, Length=236, Percent_Identity=78.3898305084746, Blast_Score=380, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17533015, Length=244, Percent_Identity=40.1639344262295, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19922098, Length=258, Percent_Identity=36.8217054263566, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.4 [H]

Molecular weight: Translated: 27724; Mature: 27593

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFIPIAKKTL
CCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHH
REQGTPEVRIATVTNFPHGNDDIEIAVAETKAAVAYGADEVDVVFPYRALIAGDETTGFE
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEECCCCEEEEECHHHEEECCCCHHHH
LVKQCKEACGDVLLKVIIETGELKEEALIKKASQICIEAGANFIKTSTGKVPVNATPEYA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHH
RMMLEVIRDMDVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLT
HHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHH
NLLNTLEVTEETADPSAY
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFIPIAKKTL
CCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHH
REQGTPEVRIATVTNFPHGNDDIEIAVAETKAAVAYGADEVDVVFPYRALIAGDETTGFE
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEECCCCEEEEECHHHEEECCCCHHHH
LVKQCKEACGDVLLKVIIETGELKEEALIKKASQICIEAGANFIKTSTGKVPVNATPEYA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHH
RMMLEVIRDMDVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLT
HHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHH
NLLNTLEVTEETADPSAY
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA