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The map label for this gene is mreC [H]

Identifier: 59710980

GI number: 59710980

Start: 405626

End: 406477

Strand: Direct

Name: mreC [H]

Synonym: VF_0373

Alternate gene names: 59710980

Gene position: 405626-406477 (Clockwise)

Preceding gene: 59710979

Following gene: 59710981

Centisome position: 14.0

GC content: 39.79

Gene sequence:

>852_bases
ATGACTCCAATCTTTGGTAGAGGTCCTTCTCTACAATTTCGCCTGTTTATTGCAGTAATGGTATCGGCTAGCCTAATGTT
AGCCGATAGTCGTTTAAATACCTTTTCCGACATACGTTACCTATTAAATAGCTTTGTTTCCCCAATTCATTACGCGGCAA
ACCTTCCTCGTACAATGTTTAATGGCATGTATGAACGGTTTAATAGCCGTAATACCCTCATGCTTGAAAATCAACGCCTT
AAGCAAGAAATGTTTGTCCAAAACAGCAATTTATTGCTCATGGAACAACTGAAACAAGAAAATAGCCGTTTACGTAATTT
ACTCGGTTCACCATTTATTCGTGATGAGAAAAAGATGGTTACGGAAGTAATGGCGGTGGATTCTGCACCTTATACACATC
AAGTGATGATTGATAAAGGTGCCGCTGATGGCGTATACGAAGGCCAGCCCGTCATTAGTGATAAAGGTATTGTTGGGCAA
ATTAACAATGTTGGAGCACATAACAGCCGAGTGTTGTTATTAACGGATGCAAATAATGCAATTCCGGTGCAGGCAGTTCG
AAATGACATTCGTGTTATTGCATCGGGCAAAGGCCACTTAGATACGATGCAACTTGAGCACATACCAACAAATACTGACT
TAAAGGTTGGGGATTTATTGGTAACTTCTGGTTTAGGTTTAGTTTACCCAGAAGGGTACCCGGTTGGGTATATATCTAAA
ATAGATAATGATAATAAGCGTCCGTTTGCGTCTATTGATATAGAAACTACGGTTGAATTTGATAAATTGCGTTATTTATT
ACTAGTATGGCCAACTGGAAAAGCACCAGAGGAGATATCTGATGGCGAGTAG

Upstream 100 bases:

>100_bases
CATGTGTGGCTCGTGGCGGCGGTAAAGCATTAGAAATGATCGATATGCACGGTGGCGATCTATTTAGTGAAGAGTAATAA
CAGTTAACGGGTGAGTGGAT

Downstream 100 bases:

>100_bases
TCATTTAATGCGTGGAAGAGTCATTATTTGGCTTTCTTTTTTAATCGCATTAACCTTGCAAGCAGCTCCTTGGCCTGGCG
CTTTAGAGGTTCTAAGACCG

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTPIFGRGPSLQFRLFIAVMVSASLMLADSRLNTFSDIRYLLNSFVSPIHYAANLPRTMFNGMYERFNSRNTLMLENQRL
KQEMFVQNSNLLLMEQLKQENSRLRNLLGSPFIRDEKKMVTEVMAVDSAPYTHQVMIDKGAADGVYEGQPVISDKGIVGQ
INNVGAHNSRVLLLTDANNAIPVQAVRNDIRVIASGKGHLDTMQLEHIPTNTDLKVGDLLVTSGLGLVYPEGYPVGYISK
IDNDNKRPFASIDIETTVEFDKLRYLLLVWPTGKAPEEISDGE

Sequences:

>Translated_283_residues
MTPIFGRGPSLQFRLFIAVMVSASLMLADSRLNTFSDIRYLLNSFVSPIHYAANLPRTMFNGMYERFNSRNTLMLENQRL
KQEMFVQNSNLLLMEQLKQENSRLRNLLGSPFIRDEKKMVTEVMAVDSAPYTHQVMIDKGAADGVYEGQPVISDKGIVGQ
INNVGAHNSRVLLLTDANNAIPVQAVRNDIRVIASGKGHLDTMQLEHIPTNTDLKVGDLLVTSGLGLVYPEGYPVGYISK
IDNDNKRPFASIDIETTVEFDKLRYLLLVWPTGKAPEEISDGE
>Mature_282_residues
TPIFGRGPSLQFRLFIAVMVSASLMLADSRLNTFSDIRYLLNSFVSPIHYAANLPRTMFNGMYERFNSRNTLMLENQRLK
QEMFVQNSNLLLMEQLKQENSRLRNLLGSPFIRDEKKMVTEVMAVDSAPYTHQVMIDKGAADGVYEGQPVISDKGIVGQI
NNVGAHNSRVLLLTDANNAIPVQAVRNDIRVIASGKGHLDTMQLEHIPTNTDLKVGDLLVTSGLGLVYPEGYPVGYISKI
DNDNKRPFASIDIETTVEFDKLRYLLLVWPTGKAPEEISDGE

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=270, Percent_Identity=54.4444444444444, Blast_Score=283, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 31664; Mature: 31533

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPIFGRGPSLQFRLFIAVMVSASLMLADSRLNTFSDIRYLLNSFVSPIHYAANLPRTMF
CCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
NGMYERFNSRNTLMLENQRLKQEMFVQNSNLLLMEQLKQENSRLRNLLGSPFIRDEKKMV
HHHHHHHCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TEVMAVDSAPYTHQVMIDKGAADGVYEGQPVISDKGIVGQINNVGAHNSRVLLLTDANNA
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCEECCCCCEEECCCCCCCCCEEEEEECCCCC
IPVQAVRNDIRVIASGKGHLDTMQLEHIPTNTDLKVGDLLVTSGLGLVYPEGYPVGYISK
EEHHHHHCCEEEEECCCCCCEEEEEEECCCCCCCEECCEEEECCCCEECCCCCCCEEEEE
IDNDNKRPFASIDIETTVEFDKLRYLLLVWPTGKAPEEISDGE
CCCCCCCCEEEEEEEEEEEHHHEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TPIFGRGPSLQFRLFIAVMVSASLMLADSRLNTFSDIRYLLNSFVSPIHYAANLPRTMF
CCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
NGMYERFNSRNTLMLENQRLKQEMFVQNSNLLLMEQLKQENSRLRNLLGSPFIRDEKKMV
HHHHHHHCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TEVMAVDSAPYTHQVMIDKGAADGVYEGQPVISDKGIVGQINNVGAHNSRVLLLTDANNA
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCEECCCCCEEECCCCCCCCCEEEEEECCCCC
IPVQAVRNDIRVIASGKGHLDTMQLEHIPTNTDLKVGDLLVTSGLGLVYPEGYPVGYISK
EEHHHHHCCEEEEECCCCCCEEEEEEECCCCCCCEECCEEEECCCCEECCCCCCCEEEEE
IDNDNKRPFASIDIETTVEFDKLRYLLLVWPTGKAPEEISDGE
CCCCCCCCEEEEEEEEEEEHHHEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2687239; 9278503; 3049542 [H]