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The map label for this gene is metH

Identifier: 59710944

GI number: 59710944

Start: 359759

End: 363439

Strand: Direct

Name: metH

Synonym: VF_0337

Alternate gene names: 59710944

Gene position: 359759-363439 (Clockwise)

Preceding gene: 59710940

Following gene: 59710946

Centisome position: 12.42

GC content: 38.28

Gene sequence:

>3681_bases
GTGGCAGGAAGCAATATAAAAGTACAAATAGAAAAGCAACTTTCAGAGCGAATTTTATTGATTGATGGTGGTATGGGCAC
CATGATTCAAGGTTATAAGTTTGAAGAGGAAGATTATAGAGGGGAACGTTTTAATAAATGGCATTGTGATCTTAAAGGTA
ACAATGATTTATTAGTTCTTTCACAACCACAAATTATAAGAGATATCCACGAAGCCTATTTAGAAGCTGGTGCTGATATC
CTTGAGACTAATACTTTTAATGCAACAACTATTGCTATGGCTGATTATGATATGGAAAGCCTTAGTGAAGAGATTAACTT
TGAAGCAGCAAAGCTTGCTCGTGAAGTTGCAGATAAATGGACCGAGAAGACACCAAATAAGCCTCGTTATGTCGCAGGAG
TGCTTGGACCAACAAACCGAACTTGTTCTATTTCTCCAGATGTAAATGATCCAGGCTTTCGTAATGTATCGTTTGATGAA
TTAGTGGAAGCTTATTCAGAGTCAACTCGAGCACTTATTAGAGGTGGCTCAGATCTTATTCTTATCGAAACTATTTTTGA
TACATTAAATGCTAAAGCGTGTTCTTTTGCTGTCGAGTCTGTTTTTGAAGAGCTTGATATTACTCTGCCCGTTATGATTT
CAGGGACAATTACTGACGCATCAGGAAGAACCTTATCGGGACAAACAACAGAAGCTTTTTATAATGCATTAAGACATGTA
AAACCTATTTCTTTTGGTCTTAATTGTGCGCTTGGTCCTGATGAATTACGTGAATATGTAAGCGATCTTTCACGTATTTC
TGAATGTTATGTTTCTGCTCACCCAAACGCTGGTTTACCTAATGCATTTGGTGAGTATGATTTATCCCCTGAAGATATGG
CTGAGCATGTTGCGGAATGGGCAAGTAGCGGATTTTTAAATCTCATTGGTGGATGTTGTGGCACCACTCCTGAACATATT
CGTCAAATGGCTTTAGTTGTTGAAGGTGTGAAACCTCGACAATTACCTGAATTACCCGTCGCTTGTCGTCTTTCCGGATT
AGAGCCTTTAACAATAGAAAAAGATTCTTTGTTTATTAATGTTGGTGAACGTACAAATGTTACTGGATCTGCTCGTTTTA
AACGCTTAATTAAAGAAGAGCTTTATGATGAAGCACTAAGTGTTGCTCAAGAGCAAGTTGAAAACGGTGCTCAAATTATC
GATATCAACATGGATGAAGGCATGCTTGATGCTGAAGCATGTATGGTTCGTTTTTTAAATCTTTGTGCATCAGAGCCTGA
AATATCTAAAGTTCCAGTGATGGTTGATTCTTCTAAATGGGAAGTAATTGAAGCTGGATTAAAGTGTATTCAAGGTAAGG
GGATAGTTAATTCAATCTCTTTAAAGGAAGGCAAAGAAAAGTTTGTACATCAAGCCAAGTTAATACGTCGCTATGGTGCT
GCAGTGATCGTTATGGCTTTTGATGAAGTCGGCCAAGCGGACACTCGTGAGCGTAAAATTGAAATTTGTACCAATGCCTA
CAATATTTTAGTTGATGAAGTTGGTTTCCCACCTGAAGATATTATTTTTGATCCTAATATTTTTGCGGTTGCTACAGGTA
TCGATGAGCATAATAACTATGCAGTAGACTTTATTGAAGCTGTTGGTGATATAAAGCGAACTCTTCCTCATGCAATGATT
TCAGGTGGTGTTTCTAACGTCTCTTTTTCTTTCCGTGGAAATAACTACGTTCGTGAAGCTATCCATGCCGTATTTTTATA
TCACTGTTTTAAAAATGGTATGGATATGGGTATCGTAAATGCAGGACAGTTGGAAATATACGATAACGTACCAGAAGATT
TGCGTGAAGCGGTTGAAGATGTAGTTCTGAATCGTAGAGATGATTCTACGGAACGTTTACTTGATATTGCAACTGAGTAT
TTAGAACGAGCTGTTGGTAAAGTTGAAGATAAATCAGCTTTAGAGTGGCGTGATTGGCCTGTTGAAAAACGTCTTGAACA
TTCTCTAGTGAAGGGGATAACAGAGTTTATTGTCGAAGATACAGAAGAAGCTCGAATCAATGCAGAAAAACCAATAGAAG
TAATTGAAGGGCCATTGATGGACGGAATGAACGTCGTCGGTGATCTTTTTGGTGAAGGAAAAATGTTCCTTCCTCAAGTA
GTAAAGTCTGCTCGTGTAATGAAACAAGCAGTTGCTCATTTAGAACCGTTTATTAATGCGTCCAAAGAAGTTGGAGCAAC
AAATGGAAAAATACTTTTAGCAACGGTAAAAGGGGATGTTCATGATATTGGTAAGAATATCGTTGGCGTTGTTTTACAGT
GTAATAATTATGAGATAATTGATCTTGGTGTCATGGTCTCTTGTGAAACTATCTTAAAAGTAGCCAAAGAAGAAAATGTA
GACATCATTGGTTTATCTGGATTGATAACACCATCATTAGATGAAATGGTCCATGTTGCTAAAGAGATGGAACGACAAGG
GTTCGATTTACCACTATTGATTGGTGGGGCAACAACTTCAAAAGCACATACAGCGGTAAAAATTGAACAAAACTATTCTC
AACCTGTTGTGTATGTCAACAATGCTTCTCGAGCTGTAGGTGTCTGTACGTCACTACTTTCCGATGAACTAAAACCTTCT
TTCGTTGAGAAGCTAGATATTGATTACGAACGAGTTAGAGAGCAGCATAGTCGTAAACAACCGCGAACTAAGCCTGTGAC
TTTAGAGGTTGCTCGAGCGAATAAAGTTGCTATTGACTGGGCTTCTTATACACCTCCTGTCCCACTGAAGCCTGGTGTAC
ATATATTTGATAATTTTGATGTTTCAACATTGCGTAATTATATTGATTGGACCCCATTTTTTATGACTTGGTCTCTTGTT
GGGAAATACCCAAAGATCTTAGATCATGAAGAAGTAGGTGAAGAAGCCAAACGATTATTTAAAGATGCAAATGATCTATT
AGATCGAGTTGAAAAAGAAGGGTTACTTAAAGCCCGTGGAATGTGTGCGCTATTTCCAGCTTCTAGTGTTGGTGATGATA
TTGAAGTTTATACTGATGAATCACGCACTAAAGTTGCAAAAGTACTTCACAATTTGCGACAACAAACGGAGAAACCGAAA
GGTTTTAACTACTGTTTATCTGATTATATAGCCCCCAAAGAATCGGGTAAAAATGATTGGATCGGTGGTTTTGCTGTAAC
TGGTGGTATTGGTGAGCGTGAACTAGCCGATGAATATAAAGCAAATGGTGATGATTATAACGCTATCATGATTCAAGCGG
TGGCTGATCGTCTAGCTGAAGCCTTTGCTGAATATTTACATGAAAAAGTACGTAAAGAAATTTGGGGTTACTCTCCTAAT
GAGACACTTTCAAATGACGATTTAATCCGTGAGAAATACCAAGGTATTCGTCCTGCTCCTGGTTACCCAGCTTGTCCTGA
ACATACAGAAAAAGGGGCTTTATGGGAGCTAATGAATGTTGAAGAATCTATTGGAATGTCTTTAACATCAAGCTATGCAA
TGTGGCCCGGTGCATCTGTGTCAGGAATGTATTTTTCACATCCGGATTCTCGTTATTTTGCGATTGCTCAGATTCAGCAA
GATCAAGCCGAAAGCTATGCCGATCGTAAAGGTTGGAATATGCTTGAAGCTGAGAAGTGGTTAGGTCCAAATTTGAATTA
A

Upstream 100 bases:

>100_bases
ATTTTCATTTTGTTGAAATAAAAATGCTTTTAGACGTCTAGATTTCTATAAAATGTGTGATAGGATTGTAACAGAAACGT
ATTATGGATGAGGTTGTACC

Downstream 100 bases:

>100_bases
TAGTGAATTGACCTTTTAAACTAAAAATGCCCATTAAATGTAATGGGCATTTTTGTATGTATCACTTATTGTTCAAAAAG
TTCTTTGTGCAAGATTTTAA

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS

Number of amino acids: Translated: 1226; Mature: 1225

Protein sequence:

>1226_residues
MAGSNIKVQIEKQLSERILLIDGGMGTMIQGYKFEEEDYRGERFNKWHCDLKGNNDLLVLSQPQIIRDIHEAYLEAGADI
LETNTFNATTIAMADYDMESLSEEINFEAAKLAREVADKWTEKTPNKPRYVAGVLGPTNRTCSISPDVNDPGFRNVSFDE
LVEAYSESTRALIRGGSDLILIETIFDTLNAKACSFAVESVFEELDITLPVMISGTITDASGRTLSGQTTEAFYNALRHV
KPISFGLNCALGPDELREYVSDLSRISECYVSAHPNAGLPNAFGEYDLSPEDMAEHVAEWASSGFLNLIGGCCGTTPEHI
RQMALVVEGVKPRQLPELPVACRLSGLEPLTIEKDSLFINVGERTNVTGSARFKRLIKEELYDEALSVAQEQVENGAQII
DINMDEGMLDAEACMVRFLNLCASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVHQAKLIRRYGA
AVIVMAFDEVGQADTRERKIEICTNAYNILVDEVGFPPEDIIFDPNIFAVATGIDEHNNYAVDFIEAVGDIKRTLPHAMI
SGGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVNAGQLEIYDNVPEDLREAVEDVVLNRRDDSTERLLDIATEY
LERAVGKVEDKSALEWRDWPVEKRLEHSLVKGITEFIVEDTEEARINAEKPIEVIEGPLMDGMNVVGDLFGEGKMFLPQV
VKSARVMKQAVAHLEPFINASKEVGATNGKILLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVSCETILKVAKEENV
DIIGLSGLITPSLDEMVHVAKEMERQGFDLPLLIGGATTSKAHTAVKIEQNYSQPVVYVNNASRAVGVCTSLLSDELKPS
FVEKLDIDYERVREQHSRKQPRTKPVTLEVARANKVAIDWASYTPPVPLKPGVHIFDNFDVSTLRNYIDWTPFFMTWSLV
GKYPKILDHEEVGEEAKRLFKDANDLLDRVEKEGLLKARGMCALFPASSVGDDIEVYTDESRTKVAKVLHNLRQQTEKPK
GFNYCLSDYIAPKESGKNDWIGGFAVTGGIGERELADEYKANGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYSPN
ETLSNDDLIREKYQGIRPAPGYPACPEHTEKGALWELMNVEESIGMSLTSSYAMWPGASVSGMYFSHPDSRYFAIAQIQQ
DQAESYADRKGWNMLEAEKWLGPNLN

Sequences:

>Translated_1226_residues
MAGSNIKVQIEKQLSERILLIDGGMGTMIQGYKFEEEDYRGERFNKWHCDLKGNNDLLVLSQPQIIRDIHEAYLEAGADI
LETNTFNATTIAMADYDMESLSEEINFEAAKLAREVADKWTEKTPNKPRYVAGVLGPTNRTCSISPDVNDPGFRNVSFDE
LVEAYSESTRALIRGGSDLILIETIFDTLNAKACSFAVESVFEELDITLPVMISGTITDASGRTLSGQTTEAFYNALRHV
KPISFGLNCALGPDELREYVSDLSRISECYVSAHPNAGLPNAFGEYDLSPEDMAEHVAEWASSGFLNLIGGCCGTTPEHI
RQMALVVEGVKPRQLPELPVACRLSGLEPLTIEKDSLFINVGERTNVTGSARFKRLIKEELYDEALSVAQEQVENGAQII
DINMDEGMLDAEACMVRFLNLCASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVHQAKLIRRYGA
AVIVMAFDEVGQADTRERKIEICTNAYNILVDEVGFPPEDIIFDPNIFAVATGIDEHNNYAVDFIEAVGDIKRTLPHAMI
SGGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVNAGQLEIYDNVPEDLREAVEDVVLNRRDDSTERLLDIATEY
LERAVGKVEDKSALEWRDWPVEKRLEHSLVKGITEFIVEDTEEARINAEKPIEVIEGPLMDGMNVVGDLFGEGKMFLPQV
VKSARVMKQAVAHLEPFINASKEVGATNGKILLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVSCETILKVAKEENV
DIIGLSGLITPSLDEMVHVAKEMERQGFDLPLLIGGATTSKAHTAVKIEQNYSQPVVYVNNASRAVGVCTSLLSDELKPS
FVEKLDIDYERVREQHSRKQPRTKPVTLEVARANKVAIDWASYTPPVPLKPGVHIFDNFDVSTLRNYIDWTPFFMTWSLV
GKYPKILDHEEVGEEAKRLFKDANDLLDRVEKEGLLKARGMCALFPASSVGDDIEVYTDESRTKVAKVLHNLRQQTEKPK
GFNYCLSDYIAPKESGKNDWIGGFAVTGGIGERELADEYKANGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYSPN
ETLSNDDLIREKYQGIRPAPGYPACPEHTEKGALWELMNVEESIGMSLTSSYAMWPGASVSGMYFSHPDSRYFAIAQIQQ
DQAESYADRKGWNMLEAEKWLGPNLN
>Mature_1225_residues
AGSNIKVQIEKQLSERILLIDGGMGTMIQGYKFEEEDYRGERFNKWHCDLKGNNDLLVLSQPQIIRDIHEAYLEAGADIL
ETNTFNATTIAMADYDMESLSEEINFEAAKLAREVADKWTEKTPNKPRYVAGVLGPTNRTCSISPDVNDPGFRNVSFDEL
VEAYSESTRALIRGGSDLILIETIFDTLNAKACSFAVESVFEELDITLPVMISGTITDASGRTLSGQTTEAFYNALRHVK
PISFGLNCALGPDELREYVSDLSRISECYVSAHPNAGLPNAFGEYDLSPEDMAEHVAEWASSGFLNLIGGCCGTTPEHIR
QMALVVEGVKPRQLPELPVACRLSGLEPLTIEKDSLFINVGERTNVTGSARFKRLIKEELYDEALSVAQEQVENGAQIID
INMDEGMLDAEACMVRFLNLCASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVHQAKLIRRYGAA
VIVMAFDEVGQADTRERKIEICTNAYNILVDEVGFPPEDIIFDPNIFAVATGIDEHNNYAVDFIEAVGDIKRTLPHAMIS
GGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVNAGQLEIYDNVPEDLREAVEDVVLNRRDDSTERLLDIATEYL
ERAVGKVEDKSALEWRDWPVEKRLEHSLVKGITEFIVEDTEEARINAEKPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVV
KSARVMKQAVAHLEPFINASKEVGATNGKILLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVSCETILKVAKEENVD
IIGLSGLITPSLDEMVHVAKEMERQGFDLPLLIGGATTSKAHTAVKIEQNYSQPVVYVNNASRAVGVCTSLLSDELKPSF
VEKLDIDYERVREQHSRKQPRTKPVTLEVARANKVAIDWASYTPPVPLKPGVHIFDNFDVSTLRNYIDWTPFFMTWSLVG
KYPKILDHEEVGEEAKRLFKDANDLLDRVEKEGLLKARGMCALFPASSVGDDIEVYTDESRTKVAKVLHNLRQQTEKPKG
FNYCLSDYIAPKESGKNDWIGGFAVTGGIGERELADEYKANGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYSPNE
TLSNDDLIREKYQGIRPAPGYPACPEHTEKGALWELMNVEESIGMSLTSSYAMWPGASVSGMYFSHPDSRYFAIAQIQQD
QAESYADRKGWNMLEAEKWLGPNLN

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain

Homologues:

Organism=Homo sapiens, GI169790923, Length=1251, Percent_Identity=52.2781774580336, Blast_Score=1308, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1217, Percent_Identity=73.6236647493837, Blast_Score=1882, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535405, Length=1252, Percent_Identity=52.0766773162939, Blast_Score=1272, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): METH_VIBF1 (Q5E814)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_203720.1
- ProteinModelPortal:   Q5E814
- SMR:   Q5E814
- STRING:   Q5E814
- GeneID:   3277291
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0337
- NMPDR:   fig|312309.3.peg.337
- eggNOG:   COG1410
- HOGENOM:   HBG289648
- OMA:   YVTDASR
- PhylomeDB:   Q5E814
- ProtClustDB:   PRK09490
- BioCyc:   VFIS312309:VF0337-MONOMER
- GO:   GO:0005622
- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223
- Gene3D:   G3DSA:3.40.50.280
- Gene3D:   G3DSA:3.20.20.20
- Gene3D:   G3DSA:3.10.196.10
- Gene3D:   G3DSA:1.10.1240.10
- Gene3D:   G3DSA:3.20.20.330
- PIRSF:   PIRSF000381
- TIGRFAMs:   TIGR02082

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans; SSF52242 Cbl-bd; SSF51717 DHP_synth_like; SSF56507 Met_synth_B12; SSF47644 Met_synth_Cbl-bd; SSF82282 S_methyl_trans

EC number: =2.1.1.13

Molecular weight: Translated: 136370; Mature: 136239

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50974 ADOMET_ACTIVATION; PS51332 B12_BINDING; PS51337 B12_BINDING_NTER; PS50970 HCY; PS50972 PTERIN_BINDING

Important sites: BINDING 806-806 BINDING 949-949 BINDING 1137-1137 BINDING 1141-1141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSNIKVQIEKQLSERILLIDGGMGTMIQGYKFEEEDYRGERFNKWHCDLKGNNDLLVL
CCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEE
SQPQIIRDIHEAYLEAGADILETNTFNATTIAMADYDMESLSEEINFEAAKLAREVADKW
CCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCHHHHHHHHCHHHHHHHHHHHHHH
TEKTPNKPRYVAGVLGPTNRTCSISPDVNDPGFRNVSFDELVEAYSESTRALIRGGSDLI
HHCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
LIETIFDTLNAKACSFAVESVFEELDITLPVMISGTITDASGRTLSGQTTEAFYNALRHV
EHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCEECCCHHHHHHHHHHHC
KPISFGLNCALGPDELREYVSDLSRISECYVSAHPNAGLPNAFGEYDLSPEDMAEHVAEW
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ASSGFLNLIGGCCGTTPEHIRQMALVVEGVKPRQLPELPVACRLSGLEPLTIEKDSLFIN
HHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHEECCCCCEEEECCCEEEE
VGERTNVTGSARFKRLIKEELYDEALSVAQEQVENGAQIIDINMDEGMLDAEACMVRFLN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
LCASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVHQAKLIRRYGA
HHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHCC
AVIVMAFDEVGQADTRERKIEICTNAYNILVDEVGFPPEDIIFDPNIFAVATGIDEHNNY
EEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEEEECCCCCCCH
AVDFIEAVGDIKRTLPHAMISGGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVN
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEC
AGQLEIYDNVPEDLREAVEDVVLNRRDDSTERLLDIATEYLERAVGKVEDKSALEWRDWP
CCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VEKRLEHSLVKGITEFIVEDTEEARINAEKPIEVIEGPLMDGMNVVGDLFGEGKMFLPQV
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHCCCHHCHHHHHHHHHCCCCCHHHHH
VKSARVMKQAVAHLEPFINASKEVGATNGKILLATVKGDVHDIGKNIVGVVLQCNNYEII
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCHHHHHHHHEEEEEEECCEEEE
DLGVMVSCETILKVAKEENVDIIGLSGLITPSLDEMVHVAKEMERQGFDLPLLIGGATTS
EECHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCC
KAHTAVKIEQNYSQPVVYVNNASRAVGVCTSLLSDELKPSFVEKLDIDYERVREQHSRKQ
CCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCC
PRTKPVTLEVARANKVAIDWASYTPPVPLKPGVHIFDNFDVSTLRNYIDWTPFFMTWSLV
CCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHCCCHHHHHHHHH
GKYPKILDHEEVGEEAKRLFKDANDLLDRVEKEGLLKARGMCALFPASSVGDDIEVYTDE
HCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEECCCCCCCCCEEEEECC
SRTKVAKVLHNLRQQTEKPKGFNYCLSDYIAPKESGKNDWIGGFAVTGGIGERELADEYK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHC
ANGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYSPNETLSNDDLIREKYQGIRPAP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCC
GYPACPEHTEKGALWELMNVEESIGMSLTSSYAMWPGASVSGMYFSHPDSRYFAIAQIQQ
CCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCEEECCCCCEEEEEHHHH
DQAESYADRKGWNMLEAEKWLGPNLN
HHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
AGSNIKVQIEKQLSERILLIDGGMGTMIQGYKFEEEDYRGERFNKWHCDLKGNNDLLVL
CCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEE
SQPQIIRDIHEAYLEAGADILETNTFNATTIAMADYDMESLSEEINFEAAKLAREVADKW
CCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCHHHHHHHHCHHHHHHHHHHHHHH
TEKTPNKPRYVAGVLGPTNRTCSISPDVNDPGFRNVSFDELVEAYSESTRALIRGGSDLI
HHCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
LIETIFDTLNAKACSFAVESVFEELDITLPVMISGTITDASGRTLSGQTTEAFYNALRHV
EHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCEECCCHHHHHHHHHHHC
KPISFGLNCALGPDELREYVSDLSRISECYVSAHPNAGLPNAFGEYDLSPEDMAEHVAEW
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ASSGFLNLIGGCCGTTPEHIRQMALVVEGVKPRQLPELPVACRLSGLEPLTIEKDSLFIN
HHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHEECCCCCEEEECCCEEEE
VGERTNVTGSARFKRLIKEELYDEALSVAQEQVENGAQIIDINMDEGMLDAEACMVRFLN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
LCASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVHQAKLIRRYGA
HHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHCC
AVIVMAFDEVGQADTRERKIEICTNAYNILVDEVGFPPEDIIFDPNIFAVATGIDEHNNY
EEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEEEECCCCCCCH
AVDFIEAVGDIKRTLPHAMISGGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVN
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEC
AGQLEIYDNVPEDLREAVEDVVLNRRDDSTERLLDIATEYLERAVGKVEDKSALEWRDWP
CCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VEKRLEHSLVKGITEFIVEDTEEARINAEKPIEVIEGPLMDGMNVVGDLFGEGKMFLPQV
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHCCCHHCHHHHHHHHHCCCCCHHHHH
VKSARVMKQAVAHLEPFINASKEVGATNGKILLATVKGDVHDIGKNIVGVVLQCNNYEII
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCHHHHHHHHEEEEEEECCEEEE
DLGVMVSCETILKVAKEENVDIIGLSGLITPSLDEMVHVAKEMERQGFDLPLLIGGATTS
EECHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCC
KAHTAVKIEQNYSQPVVYVNNASRAVGVCTSLLSDELKPSFVEKLDIDYERVREQHSRKQ
CCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCC
PRTKPVTLEVARANKVAIDWASYTPPVPLKPGVHIFDNFDVSTLRNYIDWTPFFMTWSLV
CCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHCCCHHHHHHHHH
GKYPKILDHEEVGEEAKRLFKDANDLLDRVEKEGLLKARGMCALFPASSVGDDIEVYTDE
HCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEECCCCCCCCCEEEEECC
SRTKVAKVLHNLRQQTEKPKGFNYCLSDYIAPKESGKNDWIGGFAVTGGIGERELADEYK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHC
ANGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYSPNETLSNDDLIREKYQGIRPAP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCC
GYPACPEHTEKGALWELMNVEESIGMSLTSSYAMWPGASVSGMYFSHPDSRYFAIAQIQQ
CCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCEEECCCCCEEEEEHHHH
DQAESYADRKGWNMLEAEKWLGPNLN
HHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA