Click here to switch to the map view.

The map label for this gene is zur [H]

Identifier: 59710913

GI number: 59710913

Start: 315687

End: 316136

Strand: Reverse

Name: zur [H]

Synonym: VF_0306

Alternate gene names: 59710913

Gene position: 316136-315687 (Counterclockwise)

Preceding gene: 59710920

Following gene: 59710912

Centisome position: 10.91

GC content: 37.78

Gene sequence:

>450_bases
TTGAATCGTACACAAAAACAAAAGGTTGAGCTGCTATGCCAACAACGTGGAGTAAGGTTAACTCCACAACGATTAACTGT
TTTAGAGCTGATTGTGACTCATCAGGGGGCGATCAGTGCTTATGATCTATTAGAACAATTAAAACAAATAGAACCCCAAG
CAAAGCCGCCAACCATCTATCGAGCATTAGATTTTTTGGTCACTCAAGGTTTTGTGCATAAGGTCGAATCAATAAATAGC
TATATTTCTTGCTGTGTGATCGGTGAACACGCTCATTTCTCACAACTTTTCATCTGTCGAACTTGCGATGACGTTGTTGA
ATTCCATGATAATGATATTACTAAGCAGCTAACTAAGCATGCTGAACAAATCGGCTTTTCAGTTGAGAACCATATTGTTG
AAACTCATGGCACTTGCAAGACTTGTTTAAGTAACAATAAGAAAAATTAA

Upstream 100 bases:

>100_bases
CAACTCACATAACAAATAATAATTCTCTAAATAGTGGATAAAAAATAACGAGAGTTATGTTAAACTCCTCAACTTGTTCA
AAAAATAAGACATATTTTCA

Downstream 100 bases:

>100_bases
AATAATATTTAAAGGACATCACTCACCATGCGCGCTGAATTTGTAAACCCATTCTTAGCTTCATTTATGAATGTTATTAA
AACGATGGCATCAATGGACT

Product: DNA-binding transcriptional repressor, Zn(II)-binding

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MNRTQKQKVELLCQQRGVRLTPQRLTVLELIVTHQGAISAYDLLEQLKQIEPQAKPPTIYRALDFLVTQGFVHKVESINS
YISCCVIGEHAHFSQLFICRTCDDVVEFHDNDITKQLTKHAEQIGFSVENHIVETHGTCKTCLSNNKKN

Sequences:

>Translated_149_residues
MNRTQKQKVELLCQQRGVRLTPQRLTVLELIVTHQGAISAYDLLEQLKQIEPQAKPPTIYRALDFLVTQGFVHKVESINS
YISCCVIGEHAHFSQLFICRTCDDVVEFHDNDITKQLTKHAEQIGFSVENHIVETHGTCKTCLSNNKKN
>Mature_149_residues
MNRTQKQKVELLCQQRGVRLTPQRLTVLELIVTHQGAISAYDLLEQLKQIEPQAKPPTIYRALDFLVTQGFVHKVESINS
YISCCVIGEHAHFSQLFICRTCDDVVEFHDNDITKQLTKHAEQIGFSVENHIVETHGTCKTCLSNNKKN

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=147, Percent_Identity=48.9795918367347, Blast_Score=147, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17005; Mature: 17005

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTQKQKVELLCQQRGVRLTPQRLTVLELIVTHQGAISAYDLLEQLKQIEPQAKPPTIY
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHH
RALDFLVTQGFVHKVESINSYISCCVIGEHAHFSQLFICRTCDDVVEFHDNDITKQLTKH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AEQIGFSVENHIVETHGTCKTCLSNNKKN
HHHHCCHHHHHHHHCCCHHHHHHCCCCCC
>Mature Secondary Structure
MNRTQKQKVELLCQQRGVRLTPQRLTVLELIVTHQGAISAYDLLEQLKQIEPQAKPPTIY
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHH
RALDFLVTQGFVHKVESINSYISCCVIGEHAHFSQLFICRTCDDVVEFHDNDITKQLTKH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AEQIGFSVENHIVETHGTCKTCLSNNKKN
HHHHCCHHHHHHHHCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]