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The map label for this gene is yheS [H]

Identifier: 59710825

GI number: 59710825

Start: 238452

End: 240383

Strand: Reverse

Name: yheS [H]

Synonym: VF_0218

Alternate gene names: 59710825

Gene position: 240383-238452 (Counterclockwise)

Preceding gene: 59710831

Following gene: 59710824

Centisome position: 8.3

GC content: 40.68

Gene sequence:

>1932_bases
ATGATTACCTTTTCAGACATTCAATTACTTCGTGGCGGAAAGCCATTACTAGAGCAAGCCTCTGCCACTATTCACCCTGG
TGACAAAGTCGGTTTAGTCGGAAAAAATGGCTGTGGTAAATCCACACTTTTTGCCTTAATCAAAGGTGAATTGAGTGTTG
ATGCAGGTTCAAACCGTGTTCCACATAACTGGGAAATGGCTTGGGTGGCTCAAGAAACACCTGCATTAGAACGCAAAGCC
ATTGACTATGTTATTGATGGTGACCGTGAATTTCGTGGTTTAGAAGCGCAATTAGCAAAAGCAGAAGAAGCCGATAACGG
AACTCTGGTTGCTGAATTACACGGTAAACTTGAAACCGTAGGTGGTTACACCATTAATTCTCGTGCTGCAGAATTACTTA
ATGGTTTAGGCTTTTCACAACAACAGATGGAATGGAATTTAACCCAATTCTCTGGTGGTTGGCGTATGCGTTTAAACTTA
GCACAAGCATTGATTTGTCGCTCTGATTTATTATTACTTGATGAACCAACCAACCACTTAGACTTAGATGCCGTAATGTG
GCTTGAGCGTTGGTTACAAAACTACCCGGGAACTCTATTACTCATTTCGCACGACCGTGATTTCTTAGATCCAGTAGTAA
ACCGTATTATTCACGTTGAAAACCAAAAATTGAATGAGTACACAGGTAACTACTCATCATTTGAAGTTCAACGCTCTGAA
AAACTGATCCTACAACAAGCACAATACCAGAAACAGCAGAAAAACATGGCGCACATGCAGTCATACATTGACCGCTTCCG
TTACAAAGCATCAAAAGCACGCCAAGCACAAAGCCGAATTAAAGCGTTAGAAAAAATGGAAAAAGTGCTACCAGCACAAT
TAGATAACCCATTCAGCTTTAATTTTAGAGAACCTGATGCCCTACCAAACCCAATCTTAATGATGGATGAAGTCAGTGCA
GGTTATGAAAACAATACGATTTTAGAACAAATTCGCCTAAACCTAGTTCCGGGAAGTCGTATTGGTCTTTTAGGCCGAAA
CGGTGCAGGTAAATCAACGCTAATCAAATTACTTTCAGGTGAGTTAGCTCCGCAGAGTGGCGTATTTACTTACTCTCAAG
GGGTTAAAATTGGTTACTTCGCACAGCACCAACTGGAAACCTTACACGTAGAAGAAACCCCTCTTCAGCACCTAATGCAA
ATTGCCCCTAATCATACAGAACAACAACTGCGTGATTATTTAGGCAGTTTTGGTTTCCAAGGTGATAAAGCGTTAGAAAA
AATTGGTCCTTTCTCTGGTGGTGAAAAAGCCCGTTTAGTACTGGCACTCGTAGTATGGCAAAAACCAAACATGCTATTGC
TTGATGAACCGACTAACCACCTTGATTTAGATATGCGTCAAGCCCTAACAATGGCACTACAAACCTTTGAAGGTGCAATG
GTTATTGTCAGCCACGACAGATATTTACTTCGTGCGACAACCGATGACTTATACTTAGTTCATGACCGCCAAGTAGTTCC
TTTTGATGGTGATTTAACGGATTATTACAAATGGCTAACCGAGCAGAATAAGAGCGAGCGTAAAGAACAACAGCAACAAG
ACAAGCAAGATAATCCAAGCACATCAACCAGTTTAAGTGCAGCAGAGAAAAAAGAACAAAAACGCAAAGAAGCCGAATTC
AGAAAGCTAATTGCCCCATTACGAAAAGAAGTGACTAAACTTGAAACTCGAATGGATAAGCTTAATGAAGCATTAAGCCA
AGCAGAAGAAGAGCTTGGTGACGTTTCATTATATGAAGCAGAAAACAAAAAGCGTTTAACGGAAGTTCTTGCCATTCAAG
CATCAGCAAAATCTGAACTCGAAGAAGTTGAAATGGAATGGATGGATCTTCAAGAACAAATTGAAGAAAAAGAGAATGCT
GCCAAGCAGTAA

Upstream 100 bases:

>100_bases
GACAATTTCAATGTCGACAATCACCCCTCTTACGCCTACTATGCTCATCGTATTCAAATAACTTCAAGATTCAGTCAGAT
TAAGAGAAGCAAACCACAGC

Downstream 100 bases:

>100_bases
CATTCCTTTGAATGAGCACCAATTGGCTTCTATTACCCAAGAAGCCTTTTGGTGTTTCTCATTATCCCATTATAAGAAAG
ATGGGGTAAAACAAGCAGCA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MITFSDIQLLRGGKPLLEQASATIHPGDKVGLVGKNGCGKSTLFALIKGELSVDAGSNRVPHNWEMAWVAQETPALERKA
IDYVIDGDREFRGLEAQLAKAEEADNGTLVAELHGKLETVGGYTINSRAAELLNGLGFSQQQMEWNLTQFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVMWLERWLQNYPGTLLLISHDRDFLDPVVNRIIHVENQKLNEYTGNYSSFEVQRSE
KLILQQAQYQKQQKNMAHMQSYIDRFRYKASKARQAQSRIKALEKMEKVLPAQLDNPFSFNFREPDALPNPILMMDEVSA
GYENNTILEQIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELAPQSGVFTYSQGVKIGYFAQHQLETLHVEETPLQHLMQ
IAPNHTEQQLRDYLGSFGFQGDKALEKIGPFSGGEKARLVLALVVWQKPNMLLLDEPTNHLDLDMRQALTMALQTFEGAM
VIVSHDRYLLRATTDDLYLVHDRQVVPFDGDLTDYYKWLTEQNKSERKEQQQQDKQDNPSTSTSLSAAEKKEQKRKEAEF
RKLIAPLRKEVTKLETRMDKLNEALSQAEEELGDVSLYEAENKKRLTEVLAIQASAKSELEEVEMEWMDLQEQIEEKENA
AKQ

Sequences:

>Translated_643_residues
MITFSDIQLLRGGKPLLEQASATIHPGDKVGLVGKNGCGKSTLFALIKGELSVDAGSNRVPHNWEMAWVAQETPALERKA
IDYVIDGDREFRGLEAQLAKAEEADNGTLVAELHGKLETVGGYTINSRAAELLNGLGFSQQQMEWNLTQFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVMWLERWLQNYPGTLLLISHDRDFLDPVVNRIIHVENQKLNEYTGNYSSFEVQRSE
KLILQQAQYQKQQKNMAHMQSYIDRFRYKASKARQAQSRIKALEKMEKVLPAQLDNPFSFNFREPDALPNPILMMDEVSA
GYENNTILEQIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELAPQSGVFTYSQGVKIGYFAQHQLETLHVEETPLQHLMQ
IAPNHTEQQLRDYLGSFGFQGDKALEKIGPFSGGEKARLVLALVVWQKPNMLLLDEPTNHLDLDMRQALTMALQTFEGAM
VIVSHDRYLLRATTDDLYLVHDRQVVPFDGDLTDYYKWLTEQNKSERKEQQQQDKQDNPSTSTSLSAAEKKEQKRKEAEF
RKLIAPLRKEVTKLETRMDKLNEALSQAEEELGDVSLYEAENKKRLTEVLAIQASAKSELEEVEMEWMDLQEQIEEKENA
AKQ
>Mature_643_residues
MITFSDIQLLRGGKPLLEQASATIHPGDKVGLVGKNGCGKSTLFALIKGELSVDAGSNRVPHNWEMAWVAQETPALERKA
IDYVIDGDREFRGLEAQLAKAEEADNGTLVAELHGKLETVGGYTINSRAAELLNGLGFSQQQMEWNLTQFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVMWLERWLQNYPGTLLLISHDRDFLDPVVNRIIHVENQKLNEYTGNYSSFEVQRSE
KLILQQAQYQKQQKNMAHMQSYIDRFRYKASKARQAQSRIKALEKMEKVLPAQLDNPFSFNFREPDALPNPILMMDEVSA
GYENNTILEQIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELAPQSGVFTYSQGVKIGYFAQHQLETLHVEETPLQHLMQ
IAPNHTEQQLRDYLGSFGFQGDKALEKIGPFSGGEKARLVLALVVWQKPNMLLLDEPTNHLDLDMRQALTMALQTFEGAM
VIVSHDRYLLRATTDDLYLVHDRQVVPFDGDLTDYYKWLTEQNKSERKEQQQQDKQDNPSTSTSLSAAEKKEQKRKEAEF
RKLIAPLRKEVTKLETRMDKLNEALSQAEEELGDVSLYEAENKKRLTEVLAIQASAKSELEEVEMEWMDLQEQIEEKENA
AKQ

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=527, Percent_Identity=38.3301707779886, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI10947137, Length=553, Percent_Identity=36.7088607594937, Blast_Score=326, Evalue=3e-89,
Organism=Homo sapiens, GI27881506, Length=529, Percent_Identity=37.2400756143667, Blast_Score=325, Evalue=6e-89,
Organism=Homo sapiens, GI69354671, Length=543, Percent_Identity=35.7274401473296, Blast_Score=262, Evalue=6e-70,
Organism=Homo sapiens, GI10947135, Length=543, Percent_Identity=35.7274401473296, Blast_Score=262, Evalue=9e-70,
Organism=Escherichia coli, GI1789751, Length=636, Percent_Identity=64.937106918239, Blast_Score=868, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=530, Percent_Identity=34.7169811320755, Blast_Score=311, Evalue=9e-86,
Organism=Escherichia coli, GI2367384, Length=530, Percent_Identity=31.6981132075472, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1787182, Length=640, Percent_Identity=27.8125, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1788165, Length=195, Percent_Identity=30.2564102564103, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1787758, Length=189, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786563, Length=210, Percent_Identity=30.4761904761905, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=536, Percent_Identity=39.365671641791, Blast_Score=369, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17555318, Length=524, Percent_Identity=35.6870229007634, Blast_Score=330, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17559834, Length=537, Percent_Identity=35.3817504655494, Blast_Score=315, Evalue=6e-86,
Organism=Saccharomyces cerevisiae, GI6321121, Length=536, Percent_Identity=36.1940298507463, Blast_Score=348, Evalue=1e-96,
Organism=Saccharomyces cerevisiae, GI6320874, Length=526, Percent_Identity=36.6920152091255, Blast_Score=335, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6325030, Length=401, Percent_Identity=32.4189526184539, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324314, Length=402, Percent_Identity=28.1094527363184, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323278, Length=405, Percent_Identity=28.3950617283951, Blast_Score=133, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=38.1404174573055, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24642252, Length=547, Percent_Identity=36.745886654479, Blast_Score=353, Evalue=1e-97,
Organism=Drosophila melanogaster, GI18859989, Length=547, Percent_Identity=36.745886654479, Blast_Score=353, Evalue=1e-97,
Organism=Drosophila melanogaster, GI24641342, Length=540, Percent_Identity=36.2962962962963, Blast_Score=311, Evalue=9e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72968; Mature: 72968

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFSDIQLLRGGKPLLEQASATIHPGDKVGLVGKNGCGKSTLFALIKGELSVDAGSNRV
CCCHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCEEECCCCCCC
PHNWEMAWVAQETPALERKAIDYVIDGDREFRGLEAQLAKAEEADNGTLVAELHGKLETV
CCCCEEEEEECCCCCHHHHHHHEEECCCCHHCCHHHHHHHHCCCCCCCEEEEECCCHHHC
GGYTINSRAAELLNGLGFSQQQMEWNLTQFSGGWRMRLNLAQALICRSDLLLLDEPTNHL
CCEEEHHHHHHHHHCCCCCHHHHEECCEEECCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVMWLERWLQNYPGTLLLISHDRDFLDPVVNRIIHVENQKLNEYTGNYSSFEVQRSE
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHEECCCCHHHHHCCCCCCEEEHHHH
KLILQQAQYQKQQKNMAHMQSYIDRFRYKASKARQAQSRIKALEKMEKVLPAQLDNPFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NFREPDALPNPILMMDEVSAGYENNTILEQIRLNLVPGSRIGLLGRNGAGKSTLIKLLSG
CCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHEECCCCCEEEEECCCCCHHHHHHHHHC
ELAPQSGVFTYSQGVKIGYFAQHQLETLHVEETPLQHLMQIAPNHTEQQLRDYLGSFGFQ
CCCCCCCCEEECCCCEEEEEEHHHHHEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GDKALEKIGPFSGGEKARLVLALVVWQKPNMLLLDEPTNHLDLDMRQALTMALQTFEGAM
CCHHHHHHCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIVSHDRYLLRATTDDLYLVHDRQVVPFDGDLTDYYKWLTEQNKSERKEQQQQDKQDNPS
EEEECCCEEEEECCCCEEEEECCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
TSTSLSAAEKKEQKRKEAEFRKLIAPLRKEVTKLETRMDKLNEALSQAEEELGDVSLYEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
ENKKRLTEVLAIQASAKSELEEVEMEWMDLQEQIEEKENAAKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITFSDIQLLRGGKPLLEQASATIHPGDKVGLVGKNGCGKSTLFALIKGELSVDAGSNRV
CCCHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCEEECCCCCCC
PHNWEMAWVAQETPALERKAIDYVIDGDREFRGLEAQLAKAEEADNGTLVAELHGKLETV
CCCCEEEEEECCCCCHHHHHHHEEECCCCHHCCHHHHHHHHCCCCCCCEEEEECCCHHHC
GGYTINSRAAELLNGLGFSQQQMEWNLTQFSGGWRMRLNLAQALICRSDLLLLDEPTNHL
CCEEEHHHHHHHHHCCCCCHHHHEECCEEECCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVMWLERWLQNYPGTLLLISHDRDFLDPVVNRIIHVENQKLNEYTGNYSSFEVQRSE
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHEECCCCHHHHHCCCCCCEEEHHHH
KLILQQAQYQKQQKNMAHMQSYIDRFRYKASKARQAQSRIKALEKMEKVLPAQLDNPFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NFREPDALPNPILMMDEVSAGYENNTILEQIRLNLVPGSRIGLLGRNGAGKSTLIKLLSG
CCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHEECCCCCEEEEECCCCCHHHHHHHHHC
ELAPQSGVFTYSQGVKIGYFAQHQLETLHVEETPLQHLMQIAPNHTEQQLRDYLGSFGFQ
CCCCCCCCEEECCCCEEEEEEHHHHHEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GDKALEKIGPFSGGEKARLVLALVVWQKPNMLLLDEPTNHLDLDMRQALTMALQTFEGAM
CCHHHHHHCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIVSHDRYLLRATTDDLYLVHDRQVVPFDGDLTDYYKWLTEQNKSERKEQQQQDKQDNPS
EEEECCCEEEEECCCCEEEEECCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
TSTSLSAAEKKEQKRKEAEFRKLIAPLRKEVTKLETRMDKLNEALSQAEEELGDVSLYEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
ENKKRLTEVLAIQASAKSELEEVEMEWMDLQEQIEEKENAAKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]