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The map label for this gene is yidC [H]

Identifier: 59710610

GI number: 59710610

Start: 2281

End: 3906

Strand: Reverse

Name: yidC [H]

Synonym: VF_0003

Alternate gene names: 59710610

Gene position: 3906-2281 (Counterclockwise)

Preceding gene: 59710611

Following gene: 59710609

Centisome position: 0.13

GC content: 40.77

Gene sequence:

>1626_bases
ATGGATACCCAACGTAATATTCTGTTGCTCGCACTGGCTTTAGTTTCTTTTTTACTTTTCCAACAATGGCAAGTAGAAAC
TAATCCGCAGCAACCAGCTACAGTTAGTACCGTTCAACAAACACAAACGGATGGTGATGTTCCAACTTCTTCAACAGCAA
ACAGTGATACACCAGCCGATTCAGCACAGTCTGACAAGCTGATCACAATCACAACTGATGTGCTTACTTTAAAAGTAGAT
ACATTGGGTGGTGACATCATTGAATCTGTTCTTAATAAATACGACGCAGAACTAGGCTCTAAAGCTAAATTTGTTCTTCT
TAAGAACGACGCAACACACAGCTACGTTGCTCAAAGTGGTCTAATCGGTCCTCAAGGTATCGATTCAAACTCTGGTCGTG
CTCAATTTACAGCACAAAAAACAGATTACGTTTTAGCTGAAGGCCAAAACGAATTACGTGTTCCTTTAACATTAGTGAAA
GACGGTATTACTTATACTAAAACACTAATCCTTAAACGCGACAGCTACGCTATTGATGTTGATTACACGGTTGATAACCA
ATCTTCAGCACCAGCAACTGTTGAAATGTACACAAACCTAAAGCAAAACTTAATGGATGATGGCGGTAGTCTTACTATGC
CAACATACCGTGGTGCAGCTTATTCAACAGAAGATACACGCTATAAAAAATACAGCTTTGACGACATGGAAGATAAAAAC
TTATCTATCGACATGACAAACGGTCAAGGTTGGGCGGGTATGCTACAACACTACTTCGCTTCAGCTTGGATTCCTCGCAA
CGTAAATGATGCAAAACTGACATCTCGCGTAGCAGGTGACTATGGTTACATTGGTGTTCGTATGCCTTCTGTAACTATTC
CAGCAGGTCAAGAAGCAACACTTTCTGCAACACTTTGGACAGGTCCAAAACTTCAGAAAGAAATGGCTGCTACAGCACCT
TACCTAGACCTAACTGTTGATTACGGTTGGTTATGGTTTATCGCTTCACCACTTCATAAACTATTGTCTTTCATCCAAGG
CATCGTTGTGAACTGGGGTCTAGCAATCATTGTTCTTACTTTCATCGTTCGTGGTGCAATGTACCCACTAACGAAAGCAC
AGTACACATCAATGGCTAAAATGCGTATGCTTCAACCTAAGTTGACAGCGATGCGTGAACGTATTGGCGATGACCGTCAG
CGTATGAGCCAAGAAATGATGGAGCTTTACAAGAAAGAAAAAGTAAACCCACTAGGTGGTTGTTTACCAATTCTTCTTCA
AATGCCAATCTTCATTTCACTGTACTGGGCATTAATGGAATCTGTTGAACTTCGTCATACTCCATTCTTTGGTTGGATCA
CGGATTTATCAGCACAAGACCCATACTACATCCTGCCATTATTAATGGGTGCAAGTATGTTCTTAATCCAGAAGATGAGC
CCAACAACAGTAACGGATCCAATGCAACAGAAGATCATGACGTTCATGCCTGTTATGTTCACTGTATTCTTCTTATGGTT
CCCATCTGGCCTAGTTCTTTACTGGTTAGTATCAAACATCGTAACGTTAATTCAGCAAACTCTGATTTACCGTGCTCTAG
AGAAAAAAGGCTTACATTCTAAGTAA

Upstream 100 bases:

>100_bases
GTTGGCTATCTGGCAAACGTCTATTAAAATGTCATCCTTTGAATGATGGGGGCTATGACCCCGTCCCACCCAAGCAGCAT
AAAGACAGAGAACAATAACG

Downstream 100 bases:

>100_bases
CCTTTCACTCTTGAAGTAAAACAAAGGCGGCCATTGGTCGCCTTTTTTGTTCAATGAGCATACAATATCAGTAAGCAATA
GACATAAAGAATAATCATGA

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTQTDGDVPTSSTANSDTPADSAQSDKLITITTDVLTLKVD
TLGGDIIESVLNKYDAELGSKAKFVLLKNDATHSYVAQSGLIGPQGIDSNSGRAQFTAQKTDYVLAEGQNELRVPLTLVK
DGITYTKTLILKRDSYAIDVDYTVDNQSSAPATVEMYTNLKQNLMDDGGSLTMPTYRGAAYSTEDTRYKKYSFDDMEDKN
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDAKLTSRVAGDYGYIGVRMPSVTIPAGQEATLSATLWTGPKLQKEMAATAP
YLDLTVDYGWLWFIASPLHKLLSFIQGIVVNWGLAIIVLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPILLQMPIFISLYWALMESVELRHTPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
PTTVTDPMQQKIMTFMPVMFTVFFLWFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHSK

Sequences:

>Translated_541_residues
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTQTDGDVPTSSTANSDTPADSAQSDKLITITTDVLTLKVD
TLGGDIIESVLNKYDAELGSKAKFVLLKNDATHSYVAQSGLIGPQGIDSNSGRAQFTAQKTDYVLAEGQNELRVPLTLVK
DGITYTKTLILKRDSYAIDVDYTVDNQSSAPATVEMYTNLKQNLMDDGGSLTMPTYRGAAYSTEDTRYKKYSFDDMEDKN
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDAKLTSRVAGDYGYIGVRMPSVTIPAGQEATLSATLWTGPKLQKEMAATAP
YLDLTVDYGWLWFIASPLHKLLSFIQGIVVNWGLAIIVLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPILLQMPIFISLYWALMESVELRHTPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
PTTVTDPMQQKIMTFMPVMFTVFFLWFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHSK
>Mature_541_residues
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTQTDGDVPTSSTANSDTPADSAQSDKLITITTDVLTLKVD
TLGGDIIESVLNKYDAELGSKAKFVLLKNDATHSYVAQSGLIGPQGIDSNSGRAQFTAQKTDYVLAEGQNELRVPLTLVK
DGITYTKTLILKRDSYAIDVDYTVDNQSSAPATVEMYTNLKQNLMDDGGSLTMPTYRGAAYSTEDTRYKKYSFDDMEDKN
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDAKLTSRVAGDYGYIGVRMPSVTIPAGQEATLSATLWTGPKLQKEMAATAP
YLDLTVDYGWLWFIASPLHKLLSFIQGIVVNWGLAIIVLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPILLQMPIFISLYWALMESVELRHTPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
PTTVTDPMQQKIMTFMPVMFTVFFLWFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHSK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI223718097, Length=212, Percent_Identity=28.7735849056604, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790140, Length=551, Percent_Identity=56.0798548094374, Blast_Score=603, Evalue=1e-174,
Organism=Drosophila melanogaster, GI24662345, Length=217, Percent_Identity=29.9539170506912, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356443, Length=217, Percent_Identity=29.9539170506912, Blast_Score=84, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 60601; Mature: 60601

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00496 PII_GLNB_UMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTQTDGDVPTSSTANSDTPAD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
SAQSDKLITITTDVLTLKVDTLGGDIIESVLNKYDAELGSKAKFVLLKNDATHSYVAQSG
CCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCC
LIGPQGIDSNSGRAQFTAQKTDYVLAEGQNELRVPLTLVKDGITYTKTLILKRDSYAIDV
CCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHCCCCEEEEEEEECCCEEEEE
DYTVDNQSSAPATVEMYTNLKQNLMDDGGSLTMPTYRGAAYSTEDTRYKKYSFDDMEDKN
EEEECCCCCCCEEHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCEEECCCCCCCCCC
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDAKLTSRVAGDYGYIGVRMPSVTIPAGQEAT
EEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEECCEEECCCCCCCE
LSATLWTGPKLQKEMAATAPYLDLTVDYGWLWFIASPLHKLLSFIQGIVVNWGLAIIVLT
EEEEECCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQRMSQEMMELYKKEKVNPLGG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCH
CLPILLQMPIFISLYWALMESVELRHTPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHCCHHHHHCCCC
PTTVTDPMQQKIMTFMPVMFTVFFLWFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
K
C
>Mature Secondary Structure
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTQTDGDVPTSSTANSDTPAD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
SAQSDKLITITTDVLTLKVDTLGGDIIESVLNKYDAELGSKAKFVLLKNDATHSYVAQSG
CCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCC
LIGPQGIDSNSGRAQFTAQKTDYVLAEGQNELRVPLTLVKDGITYTKTLILKRDSYAIDV
CCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHCCCCEEEEEEEECCCEEEEE
DYTVDNQSSAPATVEMYTNLKQNLMDDGGSLTMPTYRGAAYSTEDTRYKKYSFDDMEDKN
EEEECCCCCCCEEHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCEEECCCCCCCCCC
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDAKLTSRVAGDYGYIGVRMPSVTIPAGQEAT
EEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEECCEEECCCCCCCE
LSATLWTGPKLQKEMAATAPYLDLTVDYGWLWFIASPLHKLLSFIQGIVVNWGLAIIVLT
EEEEECCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQRMSQEMMELYKKEKVNPLGG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCH
CLPILLQMPIFISLYWALMESVELRHTPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHCCHHHHHCCCC
PTTVTDPMQQKIMTFMPVMFTVFFLWFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA