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The map label for this gene is lspA [H]

Identifier: 58617578

GI number: 58617578

Start: 1363905

End: 1364354

Strand: Reverse

Name: lspA [H]

Synonym: ERGA_CDS_08510

Alternate gene names: 58617578

Gene position: 1364354-1363905 (Counterclockwise)

Preceding gene: 58617579

Following gene: 58617566

Centisome position: 90.96

GC content: 26.22

Gene sequence:

>450_bases
ATGAAGAAATATATATTAATAATATGCTTGTTAGTTTTTATAGACCAAATGAGTAAATGGTATGTTATGTTCTTGTTGCA
AAATATTAATGTAATAAAAATTTGTAGTTTTGTACAAATTTCTGAGGTGTGGAATACGGGTATAAGTTTTGGTATGATGC
ATAACCTGATGTATAGTAATCTTATTTTTTGTAGTATTTCTGTTGTTATTACTTCTTTACTGTTTTATTTTTTAATATCA
GGTCTATTTGATAAAATGCCTATAGCTATTATTATTGGAGGGTCTATAGGAAACATAATCGATAGGATAAAATACGGTGC
TGTATATGATTTTATAGACATTTATGTTAAAAACTGGCACTGGCCTGCTTTTAATTTTGCAGATTCTTTTATAGTTATAG
GAATAAGCATCATCCTTATGAAAAGTATACCAGAAAATAAAAGAAAATAA

Upstream 100 bases:

>100_bases
TTAGGTTATTAGAGTTTATACGTCCTGAGTGTAAGTTTGATAGTGTTGATCAACTAAAACAGCAAATTAATATTGATATT
GTTACAGTAAAGCAAATTTT

Downstream 100 bases:

>100_bases
TTCAGTTATTATATTTTCTTTTGTAGATAATAGTTACTCTTAGTACTATACTTATTCCTTATTAATGCTATTACATTTCT
AATAAATAATAAACCCTTAT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKKYILIICLLVFIDQMSKWYVMFLLQNINVIKICSFVQISEVWNTGISFGMMHNLMYSNLIFCSISVVITSLLFYFLIS
GLFDKMPIAIIIGGSIGNIIDRIKYGAVYDFIDIYVKNWHWPAFNFADSFIVIGISIILMKSIPENKRK

Sequences:

>Translated_149_residues
MKKYILIICLLVFIDQMSKWYVMFLLQNINVIKICSFVQISEVWNTGISFGMMHNLMYSNLIFCSISVVITSLLFYFLIS
GLFDKMPIAIIIGGSIGNIIDRIKYGAVYDFIDIYVKNWHWPAFNFADSFIVIGISIILMKSIPENKRK
>Mature_149_residues
MKKYILIICLLVFIDQMSKWYVMFLLQNINVIKICSFVQISEVWNTGISFGMMHNLMYSNLIFCSISVVITSLLFYFLIS
GLFDKMPIAIIIGGSIGNIIDRIKYGAVYDFIDIYVKNWHWPAFNFADSFIVIGISIILMKSIPENKRK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=86, Percent_Identity=34.8837209302326, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17256; Mature: 17256

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYILIICLLVFIDQMSKWYVMFLLQNINVIKICSFVQISEVWNTGISFGMMHNLMYSN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LIFCSISVVITSLLFYFLISGLFDKMPIAIIIGGSIGNIIDRIKYGAVYDFIDIYVKNWH
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
WPAFNFADSFIVIGISIILMKSIPENKRK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKYILIICLLVFIDQMSKWYVMFLLQNINVIKICSFVQISEVWNTGISFGMMHNLMYSN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LIFCSISVVITSLLFYFLISGLFDKMPIAIIIGGSIGNIIDRIKYGAVYDFIDIYVKNWH
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
WPAFNFADSFIVIGISIILMKSIPENKRK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA