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The map label for this gene is rnhA [H]

Identifier: 58617483

GI number: 58617483

Start: 1204976

End: 1205437

Strand: Reverse

Name: rnhA [H]

Synonym: ERGA_CDS_07560

Alternate gene names: 58617483

Gene position: 1205437-1204976 (Counterclockwise)

Preceding gene: 58617487

Following gene: 58617482

Centisome position: 80.37

GC content: 34.2

Gene sequence:

>462_bases
TTGAGTAGTTTTATATGTTGCATGAAGGATGAATTAAATAAGGTAGTAGTTTATACTGATGGGGCTTGTTCAGGTAATCC
TGGCCCTGGAGGATGGGGTGCTGTTTTGTTATTTGATAATGGTGAAAAAACGATTTGTGGTGGTCATCCTAATACTACTA
ATAATAGGATGGAGCTGACAGCAGTTGTCCAAGCACTGAAGTTTTTAGATGTTACTTATGTTATTGATTTGTATACTGAT
AGTGTGTATGTTAAATCTGGTATTACTTCATGGATTAAAAAATGGAAAATAAATGGTTGGAGGACTGCTGATAAGTTGCC
AGTAAAGAATCTAGAACTATGGTTGGAGTTAGATAAAATTGTGAAATATCATAAAATTACTTGGTATTGGGTTAAGGCTC
ATTCAGGAAACTTGTATAATGAAAAGGCAGATATGCTTGCACGTAGTCAAATTGTTAAATAG

Upstream 100 bases:

>100_bases
GGACTATTTATATAATTATAAAATGATAAACATGTTGATTTTATTGGTAATTCTATATTTCGATATTGATATAGTAGATA
TTAGATGATACTCTTAAAGC

Downstream 100 bases:

>100_bases
GTTTTTTATATTTAGTGTTATATTATGTTATATTAGTTGTGGTGTTGTTGTACAGACAATCCTATAAATGATGCTGCTGT
ATGTTGGTCTAGTGTTTTAG

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSSFICCMKDELNKVVVYTDGACSGNPGPGGWGAVLLFDNGEKTICGGHPNTTNNRMELTAVVQALKFLDVTYVIDLYTD
SVYVKSGITSWIKKWKINGWRTADKLPVKNLELWLELDKIVKYHKITWYWVKAHSGNLYNEKADMLARSQIVK

Sequences:

>Translated_153_residues
MSSFICCMKDELNKVVVYTDGACSGNPGPGGWGAVLLFDNGEKTICGGHPNTTNNRMELTAVVQALKFLDVTYVIDLYTD
SVYVKSGITSWIKKWKINGWRTADKLPVKNLELWLELDKIVKYHKITWYWVKAHSGNLYNEKADMLARSQIVK
>Mature_152_residues
SSFICCMKDELNKVVVYTDGACSGNPGPGGWGAVLLFDNGEKTICGGHPNTTNNRMELTAVVQALKFLDVTYVIDLYTDS
VYVKSGITSWIKKWKINGWRTADKLPVKNLELWLELDKIVKYHKITWYWVKAHSGNLYNEKADMLARSQIVK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Homo sapiens, GI21359816, Length=152, Percent_Identity=36.1842105263158, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1786408, Length=138, Percent_Identity=52.8985507246377, Blast_Score=157, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI115532542, Length=144, Percent_Identity=37.5, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17505482, Length=133, Percent_Identity=33.0827067669173, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45552509, Length=142, Percent_Identity=35.9154929577465, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137476, Length=142, Percent_Identity=35.9154929577465, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 17321; Mature: 17190

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFICCMKDELNKVVVYTDGACSGNPGPGGWGAVLLFDNGEKTICGGHPNTTNNRMELT
CCCEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCHHH
AVVQALKFLDVTYVIDLYTDSVYVKSGITSWIKKWKINGWRTADKLPVKNLELWLELDKI
HHHHHHHHHHHEEEEEEECCCEEEHHHHHHHHHHHCCCCEECCCCCCCCCHHHEEEHHHH
VKYHKITWYWVKAHSGNLYNEKADMLARSQIVK
HHHEEEEEEEEEECCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SSFICCMKDELNKVVVYTDGACSGNPGPGGWGAVLLFDNGEKTICGGHPNTTNNRMELT
CCEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCHHH
AVVQALKFLDVTYVIDLYTDSVYVKSGITSWIKKWKINGWRTADKLPVKNLELWLELDKI
HHHHHHHHHHHEEEEEEECCCEEEHHHHHHHHHHHCCCCEECCCCCCCCCHHHEEEHHHH
VKYHKITWYWVKAHSGNLYNEKADMLARSQIVK
HHHEEEEEEEEEECCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA