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The map label for this gene is pyrH [H]

Identifier: 58617478

GI number: 58617478

Start: 1195332

End: 1195676

Strand: Reverse

Name: pyrH [H]

Synonym: ERGA_CDS_07510

Alternate gene names: 58617478

Gene position: 1195676-1195332 (Counterclockwise)

Preceding gene: 58617479

Following gene: 58617477

Centisome position: 79.72

GC content: 37.68

Gene sequence:

>345_bases
TTGTCTGCAGTTTCTATTACTGCAGTATGTGAGACATATATTAGGAGGCGTGCTATCCGTCATTTAGAGAAGGGAAGGAT
AGTCATTTGTGCAGCTGGGGTAGGTAATCCTTTTTTTACTACAGATACTGCTGCTGCTTTACGTGGCATAGAAATGGGAT
GTAATGTGATATTTAAAGGGACGCAAGTTGATGGTATCTACTCAGCAGATCCTAAAAAAGTTGCTGATGCAGTTAGGTAT
GATAAGATTTCTTATCGTGAGTTATTATCTCTTGATCTTAAAATTATGGATGTTGCAGCTGTATCCTTGGCTCGAGATCA
TTCAATATGTGTTTCAAATAAATAG

Upstream 100 bases:

>100_bases
TTTTTTGAATAGTATTAAAGTGACTACTTATAACTTTGGGAACACCAATGTTATCTTCTTTAAGTGAATTTATATAAATT
ACCTTGTACAATCTAGAGTC

Downstream 100 bases:

>100_bases
TTTTATTTTTACTGTGTTATTGATCACATATTATATAAAAAGTTTATTAGAATTCTTGTTGAATACTTAGTAATTTGTCT
GAATAGATATTTATAATCAG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 114; Mature: 113

Protein sequence:

>114_residues
MSAVSITAVCETYIRRRAIRHLEKGRIVICAAGVGNPFFTTDTAAALRGIEMGCNVIFKGTQVDGIYSADPKKVADAVRY
DKISYRELLSLDLKIMDVAAVSLARDHSICVSNK

Sequences:

>Translated_114_residues
MSAVSITAVCETYIRRRAIRHLEKGRIVICAAGVGNPFFTTDTAAALRGIEMGCNVIFKGTQVDGIYSADPKKVADAVRY
DKISYRELLSLDLKIMDVAAVSLARDHSICVSNK
>Mature_113_residues
SAVSITAVCETYIRRRAIRHLEKGRIVICAAGVGNPFFTTDTAAALRGIEMGCNVIFKGTQVDGIYSADPKKVADAVRYD
KISYRELLSLDLKIMDVAAVSLARDHSICVSNK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=111, Percent_Identity=49.5495495495495, Blast_Score=124, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 12423; Mature: 12291

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVSITAVCETYIRRRAIRHLEKGRIVICAAGVGNPFFTTDTAAALRGIEMGCNVIFKG
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEC
TQVDGIYSADPKKVADAVRYDKISYRELLSLDLKIMDVAAVSLARDHSICVSNK
CEECCEECCCHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
SAVSITAVCETYIRRRAIRHLEKGRIVICAAGVGNPFFTTDTAAALRGIEMGCNVIFKG
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEC
TQVDGIYSADPKKVADAVRYDKISYRELLSLDLKIMDVAAVSLARDHSICVSNK
CEECCEECCCHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA