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The map label for this gene is purQ [H]

Identifier: 58617394

GI number: 58617394

Start: 1054600

End: 1055397

Strand: Reverse

Name: purQ [H]

Synonym: ERGA_CDS_06670

Alternate gene names: 58617394

Gene position: 1055397-1054600 (Counterclockwise)

Preceding gene: 58617396

Following gene: 58617392

Centisome position: 70.36

GC content: 31.7

Gene sequence:

>798_bases
ATGAATGTAATTGTTTTATCTGGATATGGTTTGAATTGTGAAGAAGAAACTGTATTTGCTTTTTTAAAAGCTGGAGAATT
GTTATCGTGTAATGTGCAGGTGAAAGTAATGCATATTAATGAAGTGGTATCAAATCCCAGATTATTGAAAGGCTATAATG
TACTTGTAATACCTGGTGGTTTTTCATATGGTGATTATACTGGTGCTGGCAATGCTTTTGCATTAAGGATGTTAAATAAT
TTTAAAGAAGAAATAGAAGAATTTCTTACTGCTGATAAATTAGTTCTTGGCATCTGTAATGGATGTCAAGTATTAATTAG
GGTAATATCTGATTTTTCATATATCACTCTTTTAAGTAACTCTGTTAATCAGTATCAATGCAGGTGGGTGAAAGTAAAAG
TAAACCAGTTAAATAATTCAGTATGGTTGTATGAGTTAGATGAATTGTATATTCCAGTTGCACATGGAGAAGGACGCTTT
TTTCTTGAGAGTAATTCTATTGATGTATCTATTAAAGATAAAATTGCGTTACAATATGTTACAGATAAAGGTAATCTTGC
AAATCAACAATTTCCACACAATCCAAATGGGTCGGTATATGATATAGCTGCGTTATCAAGTAACAATGGTAGAGTGCTGG
TAATGATGCCACATCCAGAAAGAGCTGTATTTTTCTTACAGCAAGATAATTGGAGTGAAATTAAGGAACAATGCTTACGT
TCTGATATCCCTTATCCCATTTATGGTGATGGAATAAAGATTTTTTGCAATGCTGTGAAATATTTTCATAGTATGTAA

Upstream 100 bases:

>100_bases
ATTTAATAATCTAGTTTTTTAAATAAAATATTGATATAAAGAAAGTTCAATAGTTTGCTTTTATGTAAATCTAAATTTAT
ATACTTATTGTAGATTAATA

Downstream 100 bases:

>100_bases
TGAATAGATTTTATTAATAACAAGTAATAACAATGTTAATACCATATAAATAAATATGCATATATGATAACTTTAGTATT
AACATATAATATGTTGAATT

Product: phosphoribosylformylglycinamidine synthase

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MNVIVLSGYGLNCEEETVFAFLKAGELLSCNVQVKVMHINEVVSNPRLLKGYNVLVIPGGFSYGDYTGAGNAFALRMLNN
FKEEIEEFLTADKLVLGICNGCQVLIRVISDFSYITLLSNSVNQYQCRWVKVKVNQLNNSVWLYELDELYIPVAHGEGRF
FLESNSIDVSIKDKIALQYVTDKGNLANQQFPHNPNGSVYDIAALSSNNGRVLVMMPHPERAVFFLQQDNWSEIKEQCLR
SDIPYPIYGDGIKIFCNAVKYFHSM

Sequences:

>Translated_265_residues
MNVIVLSGYGLNCEEETVFAFLKAGELLSCNVQVKVMHINEVVSNPRLLKGYNVLVIPGGFSYGDYTGAGNAFALRMLNN
FKEEIEEFLTADKLVLGICNGCQVLIRVISDFSYITLLSNSVNQYQCRWVKVKVNQLNNSVWLYELDELYIPVAHGEGRF
FLESNSIDVSIKDKIALQYVTDKGNLANQQFPHNPNGSVYDIAALSSNNGRVLVMMPHPERAVFFLQQDNWSEIKEQCLR
SDIPYPIYGDGIKIFCNAVKYFHSM
>Mature_265_residues
MNVIVLSGYGLNCEEETVFAFLKAGELLSCNVQVKVMHINEVVSNPRLLKGYNVLVIPGGFSYGDYTGAGNAFALRMLNN
FKEEIEEFLTADKLVLGICNGCQVLIRVISDFSYITLLSNSVNQYQCRWVKVKVNQLNNSVWLYELDELYIPVAHGEGRF
FLESNSIDVSIKDKIALQYVTDKGNLANQQFPHNPNGSVYDIAALSSNNGRVLVMMPHPERAVFFLQQDNWSEIKEQCLR
SDIPYPIYGDGIKIFCNAVKYFHSM

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=246, Percent_Identity=30.8943089430894, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI48994899, Length=240, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17553022, Length=279, Percent_Identity=26.8817204301075, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321498, Length=283, Percent_Identity=31.4487632508834, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24582111, Length=243, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24582109, Length=243, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17137292, Length=243, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 29917; Mature: 29917

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIVLSGYGLNCEEETVFAFLKAGELLSCNVQVKVMHINEVVSNPRLLKGYNVLVIPGG
CEEEEEECCCCCCCHHHEEEEEECCCEEEEEEEEEEEEEEHHHCCCEEEECCEEEEECCC
FSYGDYTGAGNAFALRMLNNFKEEIEEFLTADKLVLGICNGCQVLIRVISDFSYITLLSN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCEEEEECC
SVNQYQCRWVKVKVNQLNNSVWLYELDELYIPVAHGEGRFFLESNSIDVSIKDKIALQYV
CCCCEEEEEEEEEEEECCCEEEEEEECEEEEEEEECCCEEEEECCCEEEEEECEEEEEEE
TDKGNLANQQFPHNPNGSVYDIAALSSNNGRVLVMMPHPERAVFFLQQDNWSEIKEQCLR
ECCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHH
SDIPYPIYGDGIKIFCNAVKYFHSM
CCCCCCEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVIVLSGYGLNCEEETVFAFLKAGELLSCNVQVKVMHINEVVSNPRLLKGYNVLVIPGG
CEEEEEECCCCCCCHHHEEEEEECCCEEEEEEEEEEEEEEHHHCCCEEEECCEEEEECCC
FSYGDYTGAGNAFALRMLNNFKEEIEEFLTADKLVLGICNGCQVLIRVISDFSYITLLSN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCEEEEECC
SVNQYQCRWVKVKVNQLNNSVWLYELDELYIPVAHGEGRFFLESNSIDVSIKDKIALQYV
CCCCEEEEEEEEEEEECCCEEEEEEECEEEEEEEECCCEEEEECCCEEEEEECEEEEEEE
TDKGNLANQQFPHNPNGSVYDIAALSSNNGRVLVMMPHPERAVFFLQQDNWSEIKEQCLR
ECCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHH
SDIPYPIYGDGIKIFCNAVKYFHSM
CCCCCCEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA