Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 58617324

GI number: 58617324

Start: 967903

End: 968697

Strand: Reverse

Name: dapB

Synonym: ERGA_CDS_05970

Alternate gene names: 58617324

Gene position: 968697-967903 (Counterclockwise)

Preceding gene: 58617325

Following gene: 58617323

Centisome position: 64.58

GC content: 34.84

Gene sequence:

>795_bases
ATGAATAAAGTGAAAGTAGGTATAGTTGGTTGTTTAGGTAGGCAGGGTAGGCATTTGGTGAGTGAAATATCTGCAAGTGA
TATTGCTGAGGTAAGTGCAGGACTTGTTCGTATAGGCAGTGAATATGTTGGTAAGGTATTAGGTGTCGTCATTGGATGTA
ATTGTGATGCGAAAATTACTGATTCTTTAGAGCATCTTTTTGATGTTTCAGATGTTGTCATAGAATTTACTAATCCTAAT
ACCATGATAGAATGTATGAAAATGGCTGAACTAAAAAAGAAACCTATGGTAAGTGGTACTACTGGAATAAGTGAAGATAT
GGTTTTTCAAGATTATATTAAGAGTGTACCTTTTTTGTGGAGTGCTAACTTAAGTTTTAGTATGAATATACTGTTAAAAT
TAGTTGAGGATGCTACAAGAATGTTGTCTGGTTATGATGTAGAAATATGGGAAATACATCATAGGTATAAAAAGGATTCT
CCATCTGGTACATCTTTGATGTTGGGAAAAGCTGCAGCAAGGGGTATGAATGTTCAATTTAGGATGAATCAGTATATAAA
AGGTGGTCAGGAAAGTAGACAAGATAATAAGAGTATAGGATATGCTGTGTCTAGAGGTGGGGTAGGACTTAGTGATCATA
AAATTATCTTTGCTGGTGATGAGGATGTTATAGAATTTAGTCATAGAGCTACGAACAAAAATGTTTATGCAAAAGGCGCT
CTAAAGGCAGCTTTATGGTTAATAGGACAACCTTGTGGTATATATACAATGTCAGATATGATGGTGACACAGTAA

Upstream 100 bases:

>100_bases
AAATTATAATTGGTCAAGTCATAGATTGTTCTAAATTAGATAGTAAAGATAGTCCTTTAGTATATTATAGAGGACAGTAT
ATGGCTATAGGTGATCCATT

Downstream 100 bases:

>100_bases
TTATTTTGGTATAATAAGGTATGTCGATAGAGATTCATGCTTCAGCTAAAAATTTGAATTTATGGTATGATAGTAACCAA
GTTTTACATAATATCAGTTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNKVKVGIVGCLGRQGRHLVSEISASDIAEVSAGLVRIGSEYVGKVLGVVIGCNCDAKITDSLEHLFDVSDVVIEFTNPN
TMIECMKMAELKKKPMVSGTTGISEDMVFQDYIKSVPFLWSANLSFSMNILLKLVEDATRMLSGYDVEIWEIHHRYKKDS
PSGTSLMLGKAAARGMNVQFRMNQYIKGGQESRQDNKSIGYAVSRGGVGLSDHKIIFAGDEDVIEFSHRATNKNVYAKGA
LKAALWLIGQPCGIYTMSDMMVTQ

Sequences:

>Translated_264_residues
MNKVKVGIVGCLGRQGRHLVSEISASDIAEVSAGLVRIGSEYVGKVLGVVIGCNCDAKITDSLEHLFDVSDVVIEFTNPN
TMIECMKMAELKKKPMVSGTTGISEDMVFQDYIKSVPFLWSANLSFSMNILLKLVEDATRMLSGYDVEIWEIHHRYKKDS
PSGTSLMLGKAAARGMNVQFRMNQYIKGGQESRQDNKSIGYAVSRGGVGLSDHKIIFAGDEDVIEFSHRATNKNVYAKGA
LKAALWLIGQPCGIYTMSDMMVTQ
>Mature_264_residues
MNKVKVGIVGCLGRQGRHLVSEISASDIAEVSAGLVRIGSEYVGKVLGVVIGCNCDAKITDSLEHLFDVSDVVIEFTNPN
TMIECMKMAELKKKPMVSGTTGISEDMVFQDYIKSVPFLWSANLSFSMNILLKLVEDATRMLSGYDVEIWEIHHRYKKDS
PSGTSLMLGKAAARGMNVQFRMNQYIKGGQESRQDNKSIGYAVSRGGVGLSDHKIIFAGDEDVIEFSHRATNKNVYAKGA
LKAALWLIGQPCGIYTMSDMMVTQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=263, Percent_Identity=32.6996197718631, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_EHRRG (Q5FFT0)

Other databases:

- EMBL:   CR925677
- RefSeq:   YP_196523.1
- ProteinModelPortal:   Q5FFT0
- SMR:   Q5FFT0
- STRING:   Q5FFT0
- GeneID:   3268445
- GenomeReviews:   CR925677_GR
- KEGG:   erg:ERGA_CDS_05970
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- BioCyc:   ERUM302409:ERGA_CDS_05970-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28973; Mature: 28973

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVKVGIVGCLGRQGRHLVSEISASDIAEVSAGLVRIGSEYVGKVLGVVIGCNCDAKIT
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHH
DSLEHLFDVSDVVIEFTNPNTMIECMKMAELKKKPMVSGTTGISEDMVFQDYIKSVPFLW
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCEEE
SANLSFSMNILLKLVEDATRMLSGYDVEIWEIHHRYKKDSPSGTSLMLGKAAARGMNVQF
ECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCEEEEEHHHHCCCCEEE
RMNQYIKGGQESRQDNKSIGYAVSRGGVGLSDHKIIFAGDEDVIEFSHRATNKNVYAKGA
EEHHHHCCCCHHHCCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEHHH
LKAALWLIGQPCGIYTMSDMMVTQ
HHHHHHHHCCCCCCEEECCEEECC
>Mature Secondary Structure
MNKVKVGIVGCLGRQGRHLVSEISASDIAEVSAGLVRIGSEYVGKVLGVVIGCNCDAKIT
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHH
DSLEHLFDVSDVVIEFTNPNTMIECMKMAELKKKPMVSGTTGISEDMVFQDYIKSVPFLW
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCEEE
SANLSFSMNILLKLVEDATRMLSGYDVEIWEIHHRYKKDSPSGTSLMLGKAAARGMNVQF
ECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCEEEEEHHHHCCCCEEE
RMNQYIKGGQESRQDNKSIGYAVSRGGVGLSDHKIIFAGDEDVIEFSHRATNKNVYAKGA
EEHHHHCCCCHHHCCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEHHH
LKAALWLIGQPCGIYTMSDMMVTQ
HHHHHHHHCCCCCCEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA