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The map label for this gene is lepB [H]

Identifier: 58617107

GI number: 58617107

Start: 627646

End: 628362

Strand: Reverse

Name: lepB [H]

Synonym: ERGA_CDS_03800

Alternate gene names: 58617107

Gene position: 628362-627646 (Counterclockwise)

Preceding gene: 58617108

Following gene: 58617106

Centisome position: 41.89

GC content: 30.68

Gene sequence:

>717_bases
TTGAAAAAAAGTTTCCCTGTTCGTGAGTTTATCTCAACATTTATTCTTGCTACGCTAACTGTTTTAGCGATAAGGGTTTT
TTTATTTGAGCCATTTCACATACCCTCCGGTTCAATGAAAAGTACATTATTAGTGGGAGATTATATATTTGTTAGTAAAT
ATAGTTATGGTTACAGTAGGTATTCTTTTCCATTCTATCTTCCAATAATAAAAGGTCGCATTTTCCCAAAAACACCAAAA
CCTGGTGATGTTGTTGTATTTCGTCCACCTAAAGATCCAGGACTTCATTATATAAAAAGAGTAATTGGTATACCAGGTGA
TAAAGTACAAATTATTAATGGTTTTCTTTATATAAATGGAAATAAAATGCAGTATAAAAAGGTTAGTGATTTTATAGATG
AAGATGATGGAAAAGCAATCTGTCGTTACTTAGAAACATTACCTAATGGTAATACACATGAGGTATTAGATGATATTCAA
GATAGTCCACTTGATAACACACCAGTATATACTGTACCAGAAGATCATGTTTTTGTACTAGGTGATAATCGAGATAATTC
AAGGGATAGTCGATTTATTACAGATGTTGGGTATATTCCTCTTAAAAATATAATAGGAAAAGCTCATGTAATAGCATTAT
CATTCACAAAATCTAAAGATGGCAGTTTTTTGCCATTTAAATTAAGATCAGATAGAGTATGGCATGCAATTAATTAA

Upstream 100 bases:

>100_bases
TAGAAGATATAAATGGATCTCGATTTGTCATCAATAATCCAAGTGCAAAATCTAAGTGCGGATGCGGTAATAGTTTTTCT
ATATAGTTCATGGTATAACC

Downstream 100 bases:

>100_bases
GATATATTATGATTAATAAAAGATCATTACTGGCAAGTTTTATAAATTTACCGTATAGCTTATTCATTACCTTTAAAGGT
ATGTATATAACATTACGTTA

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKKSFPVREFISTFILATLTVLAIRVFLFEPFHIPSGSMKSTLLVGDYIFVSKYSYGYSRYSFPFYLPIIKGRIFPKTPK
PGDVVVFRPPKDPGLHYIKRVIGIPGDKVQIINGFLYINGNKMQYKKVSDFIDEDDGKAICRYLETLPNGNTHEVLDDIQ
DSPLDNTPVYTVPEDHVFVLGDNRDNSRDSRFITDVGYIPLKNIIGKAHVIALSFTKSKDGSFLPFKLRSDRVWHAIN

Sequences:

>Translated_238_residues
MKKSFPVREFISTFILATLTVLAIRVFLFEPFHIPSGSMKSTLLVGDYIFVSKYSYGYSRYSFPFYLPIIKGRIFPKTPK
PGDVVVFRPPKDPGLHYIKRVIGIPGDKVQIINGFLYINGNKMQYKKVSDFIDEDDGKAICRYLETLPNGNTHEVLDDIQ
DSPLDNTPVYTVPEDHVFVLGDNRDNSRDSRFITDVGYIPLKNIIGKAHVIALSFTKSKDGSFLPFKLRSDRVWHAIN
>Mature_238_residues
MKKSFPVREFISTFILATLTVLAIRVFLFEPFHIPSGSMKSTLLVGDYIFVSKYSYGYSRYSFPFYLPIIKGRIFPKTPK
PGDVVVFRPPKDPGLHYIKRVIGIPGDKVQIINGFLYINGNKMQYKKVSDFIDEDDGKAICRYLETLPNGNTHEVLDDIQ
DSPLDNTPVYTVPEDHVFVLGDNRDNSRDSRFITDVGYIPLKNIIGKAHVIALSFTKSKDGSFLPFKLRSDRVWHAIN

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=264, Percent_Identity=35.9848484848485, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 27131; Mature: 27131

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSFPVREFISTFILATLTVLAIRVFLFEPFHIPSGSMKSTLLVGDYIFVSKYSYGYSR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECEEEEEEECCCCEE
YSFPFYLPIIKGRIFPKTPKPGDVVVFRPPKDPGLHYIKRVIGIPGDKVQIINGFLYING
CCCCEEEEECCCEECCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEEEEEC
NKMQYKKVSDFIDEDDGKAICRYLETLPNGNTHEVLDDIQDSPLDNTPVYTVPEDHVFVL
CEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEECCCCEEEEE
GDNRDNSRDSRFITDVGYIPLKNIIGKAHVIALSFTKSKDGSFLPFKLRSDRVWHAIN
ECCCCCCCCCEEEEECCCCCHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCEEEECC
>Mature Secondary Structure
MKKSFPVREFISTFILATLTVLAIRVFLFEPFHIPSGSMKSTLLVGDYIFVSKYSYGYSR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECEEEEEEECCCCEE
YSFPFYLPIIKGRIFPKTPKPGDVVVFRPPKDPGLHYIKRVIGIPGDKVQIINGFLYING
CCCCEEEEECCCEECCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEEEEEC
NKMQYKKVSDFIDEDDGKAICRYLETLPNGNTHEVLDDIQDSPLDNTPVYTVPEDHVFVL
CEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEECCCCEEEEE
GDNRDNSRDSRFITDVGYIPLKNIIGKAHVIALSFTKSKDGSFLPFKLRSDRVWHAIN
ECCCCCCCCCEEEEECCCCCHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA