Click here to switch to the map view.

The map label for this gene is ribH [H]

Identifier: 58617040

GI number: 58617040

Start: 516909

End: 517358

Strand: Reverse

Name: ribH [H]

Synonym: ERGA_CDS_03130

Alternate gene names: 58617040

Gene position: 517358-516909 (Counterclockwise)

Preceding gene: 58617041

Following gene: 58617039

Centisome position: 34.49

GC content: 33.33

Gene sequence:

>450_bases
ATGCCTAACAATAAAATAAAAATGCTAGTTGTAGTATCACAATTCTATCCTGAAATTACAGAACTTATGTTAAACGCAGC
AGTTGCCGTATTTCAAGAACATACAGAACCTGTAGAATATGATGTAGTATATGTACCAGGATCTTTTGAAATACCAGCAG
CTATAACATTTGCAATACTAAGTGACAAGTATCATTATGATGGCTATGTTGCCTTAGGTTGTGTAATAAAAGGAGAAACT
GATCATTATTATTATGTTTCTAAAGGAGTAACTTTATCTCTTAGTGAAATTGCTACCAATCATGCTGTTCCTATGGGCTT
TGGAGTAATTACAGCTGAAACTAAAGAACTAGCATTAGCAAGAGCAGATATGAATAAAAAAAATGTCGGGGGAAAAGCTG
CTAAAGCAGCATTAGCTATGGTCACATTACATAAAAAATTCTTACGCTAA

Upstream 100 bases:

>100_bases
AGTAATTCTATTACTATAATACAACAATTAATAATAAAAGCTTATATAGGAAGAAAGTTTAATTTAAAACATGATTTATA
ATAACTAAAAAAGAGTTAAT

Downstream 100 bases:

>100_bases
AATTATGAAAGATAACATACACTATCAATCACTTTGGCAGTCAAAAAAAACAACAACAAGGTTTCTTGCTGTACAAGGTA
CCTATGCAATGACATTTAAC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MPNNKIKMLVVVSQFYPEITELMLNAAVAVFQEHTEPVEYDVVYVPGSFEIPAAITFAILSDKYHYDGYVALGCVIKGET
DHYYYVSKGVTLSLSEIATNHAVPMGFGVITAETKELALARADMNKKNVGGKAAKAALAMVTLHKKFLR

Sequences:

>Translated_149_residues
MPNNKIKMLVVVSQFYPEITELMLNAAVAVFQEHTEPVEYDVVYVPGSFEIPAAITFAILSDKYHYDGYVALGCVIKGET
DHYYYVSKGVTLSLSEIATNHAVPMGFGVITAETKELALARADMNKKNVGGKAAKAALAMVTLHKKFLR
>Mature_148_residues
PNNKIKMLVVVSQFYPEITELMLNAAVAVFQEHTEPVEYDVVYVPGSFEIPAAITFAILSDKYHYDGYVALGCVIKGETD
HYYYVSKGVTLSLSEIATNHAVPMGFGVITAETKELALARADMNKKNVGGKAAKAALAMVTLHKKFLR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=141, Percent_Identity=31.9148936170213, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16360; Mature: 16229

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNNKIKMLVVVSQFYPEITELMLNAAVAVFQEHTEPVEYDVVYVPGSFEIPAAITFAIL
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHEEEEEE
SDKYHYDGYVALGCVIKGETDHYYYVSKGVTLSLSEIATNHAVPMGFGVITAETKELALA
CCCCCCCCEEEEEEEEECCCCCEEEEECCCEEEHHHHHCCCCCCCCEEEEEECHHHHHHH
RADMNKKNVGGKAAKAALAMVTLHKKFLR
HCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNNKIKMLVVVSQFYPEITELMLNAAVAVFQEHTEPVEYDVVYVPGSFEIPAAITFAIL
CCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHEEEEEE
SDKYHYDGYVALGCVIKGETDHYYYVSKGVTLSLSEIATNHAVPMGFGVITAETKELALA
CCCCCCCCEEEEEEEEECCCCCEEEEECCCEEEHHHHHCCCCCCCCEEEEEECHHHHHHH
RADMNKKNVGGKAAKAALAMVTLHKKFLR
HCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA