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The map label for this gene is dapA [H]

Identifier: 58616994

GI number: 58616994

Start: 442053

End: 442970

Strand: Reverse

Name: dapA [H]

Synonym: ERGA_CDS_02670

Alternate gene names: 58616994

Gene position: 442970-442053 (Counterclockwise)

Preceding gene: 58616995

Following gene: 58616993

Centisome position: 29.53

GC content: 31.37

Gene sequence:

>918_bases
TTGATTAAAAATATTGAGGTACTACAGATGAACAGTGAGAGACTTAAAGGTGTATTTACTGCACTTGTTACACCGTTTAA
AAACGATTTTTCTGTAGATCAAGATGCATTTACTCAGCTTATTGAGTATCAGATTAGCAATAATGTTCATGGTTTAGTAC
CATGTGGCAGTACTGGAGAAAGTACAACTTTAACTTTTGAAGAATACTGTGAAATAATAAAACTATGTATTAAAACTACA
AATAACAGAGTTCCAATAATAGCTGGTTCAGGTTCATGTTCTACACAAGAAACAATTAAACGTACATTATTCGTTAATTC
CTTAAATGTAGATGCAGCATTGGTAGTAGTTCCATATTATAATAGACCAACTGATGAAGGAATATATCAACACTTTAAGG
CAGTACATGATGCAACTAATATTCCTATCATTATATATAATATCCCAAAAAGAACTGGAGTAGATGTAAGCGATACATTA
CTTGCACGTATCTTATCTTTACCTAGAGTAATAGGAGTGAAGGATGCAACTTGTGATATAAGTCGGCCACTGAATTTAAA
AACATTGGTACAGAAAGATATAGTTCTGTTCTCAGGAGATGATTTTACATGTTTAGCATTCAATGCTCATGGTGGTTCTG
GATGCATATCTGCTGTTTCAAATGTAGCACCTAAAATATGTTCAGATATGCAAAGTGCTTTCTTTTCCAATAATATAAAA
GAAGCTATAGAAATAAGTAAGACAATACTTAAATTATCACAAGCATTATTCTGTGAATCTAACCCATCACCGGCAAAATA
TGCCTTGAGCTTAATTACAGAATATATATCTCCAATAGTAAGATTACCATTAGTAGAATTAACTCAAGAGAATAAATTAA
AAGTTGAAAATACATTAAAAGAGCTAGGGTTTATCTAA

Upstream 100 bases:

>100_bases
TTAATCATATAAACAACAATATTCAACTAAACAAAGTAATAAATCTCTATTGACAAAGTTTACAATAAAGACAAATATGA
ATTAATAAACTAGTGTATTA

Downstream 100 bases:

>100_bases
AAAAAATATCATTTCAATTAAAGCTATCATTATATAGCATAATTATAGTAATGTTTGTATGTTACTTCATTAGATAATAT
GCTTGACATAATATATTATA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MIKNIEVLQMNSERLKGVFTALVTPFKNDFSVDQDAFTQLIEYQISNNVHGLVPCGSTGESTTLTFEEYCEIIKLCIKTT
NNRVPIIAGSGSCSTQETIKRTLFVNSLNVDAALVVVPYYNRPTDEGIYQHFKAVHDATNIPIIIYNIPKRTGVDVSDTL
LARILSLPRVIGVKDATCDISRPLNLKTLVQKDIVLFSGDDFTCLAFNAHGGSGCISAVSNVAPKICSDMQSAFFSNNIK
EAIEISKTILKLSQALFCESNPSPAKYALSLITEYISPIVRLPLVELTQENKLKVENTLKELGFI

Sequences:

>Translated_305_residues
MIKNIEVLQMNSERLKGVFTALVTPFKNDFSVDQDAFTQLIEYQISNNVHGLVPCGSTGESTTLTFEEYCEIIKLCIKTT
NNRVPIIAGSGSCSTQETIKRTLFVNSLNVDAALVVVPYYNRPTDEGIYQHFKAVHDATNIPIIIYNIPKRTGVDVSDTL
LARILSLPRVIGVKDATCDISRPLNLKTLVQKDIVLFSGDDFTCLAFNAHGGSGCISAVSNVAPKICSDMQSAFFSNNIK
EAIEISKTILKLSQALFCESNPSPAKYALSLITEYISPIVRLPLVELTQENKLKVENTLKELGFI
>Mature_305_residues
MIKNIEVLQMNSERLKGVFTALVTPFKNDFSVDQDAFTQLIEYQISNNVHGLVPCGSTGESTTLTFEEYCEIIKLCIKTT
NNRVPIIAGSGSCSTQETIKRTLFVNSLNVDAALVVVPYYNRPTDEGIYQHFKAVHDATNIPIIIYNIPKRTGVDVSDTL
LARILSLPRVIGVKDATCDISRPLNLKTLVQKDIVLFSGDDFTCLAFNAHGGSGCISAVSNVAPKICSDMQSAFFSNNIK
EAIEISKTILKLSQALFCESNPSPAKYALSLITEYISPIVRLPLVELTQENKLKVENTLKELGFI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=289, Percent_Identity=24.9134948096886, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI13540533, Length=304, Percent_Identity=22.3684210526316, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788823, Length=289, Percent_Identity=35.6401384083045, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1786463, Length=250, Percent_Identity=28, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI87082415, Length=302, Percent_Identity=23.841059602649, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789620, Length=229, Percent_Identity=25.764192139738, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33574; Mature: 33574

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNIEVLQMNSERLKGVFTALVTPFKNDFSVDQDAFTQLIEYQISNNVHGLVPCGSTGE
CCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
STTLTFEEYCEIIKLCIKTTNNRVPIIAGSGSCSTQETIKRTLFVNSLNVDAALVVVPYY
CCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHEECCCCCEEEEEEECC
NRPTDEGIYQHFKAVHDATNIPIIIYNIPKRTGVDVSDTLLARILSLPRVIGVKDATCDI
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCC
SRPLNLKTLVQKDIVLFSGDDFTCLAFNAHGGSGCISAVSNVAPKICSDMQSAFFSNNIK
CCCCCHHHHHHHCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
EAIEISKTILKLSQALFCESNPSPAKYALSLITEYISPIVRLPLVELTQENKLKVENTLK
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHH
ELGFI
HHCCC
>Mature Secondary Structure
MIKNIEVLQMNSERLKGVFTALVTPFKNDFSVDQDAFTQLIEYQISNNVHGLVPCGSTGE
CCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
STTLTFEEYCEIIKLCIKTTNNRVPIIAGSGSCSTQETIKRTLFVNSLNVDAALVVVPYY
CCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHEECCCCCEEEEEEECC
NRPTDEGIYQHFKAVHDATNIPIIIYNIPKRTGVDVSDTLLARILSLPRVIGVKDATCDI
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCC
SRPLNLKTLVQKDIVLFSGDDFTCLAFNAHGGSGCISAVSNVAPKICSDMQSAFFSNNIK
CCCCCHHHHHHHCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
EAIEISKTILKLSQALFCESNPSPAKYALSLITEYISPIVRLPLVELTQENKLKVENTLK
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHH
ELGFI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA