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The map label for this gene is lolC [H]

Identifier: 58616806

GI number: 58616806

Start: 126842

End: 128077

Strand: Reverse

Name: lolC [H]

Synonym: ERGA_CDS_00790

Alternate gene names: 58616806

Gene position: 128077-126842 (Counterclockwise)

Preceding gene: 58616810

Following gene: 58616805

Centisome position: 8.54

GC content: 31.23

Gene sequence:

>1236_bases
ATGTTATTTAAGTTTGAGTTGATGCTAGCATTGCGTTACTTACAATCTAACAGAAGTCAATTTTTATGTTCTATGATTAC
TATGTTATCATTTATTGGGATTACCTTAGGAGTCGCCACACTAATTATAGTGATGTCCGTAATGAACGGATTTGGCGAAA
AGTTGTTAAATTGTATTGTAGGAGTTAATGGTCAAGTAGCAATTTACTTCAACAATAATGAGAAAGATACTAATTATCAT
GACGTTGCAAAATTAATTAAAGATATTCCTGGTGTAATAGATGCAATTCCCATAACTGAAAACCAAGCTATGGCAAAATC
CGAACAAAGTGTTTCCGGAATCATAGTAAGAGGAATCAGTAAACAAGATCTACTAAGAAAAAACATAATCGCTGACAACA
TCGTAAGAGGTAATATATCTGACCTAGACAATGGTATAGTAATAGGTATAAAATTGGCAGAAATTCTGAATGTGAATTAT
GGAGATAAAATAACCATTCTCTCATCAGATAGTATTCCTACAGTAATAGGTAGTATCCCACGCATGAAGAGCTACAAAGT
TATTGCAGTATTCGATTTAGGAATGTACGAATATGATAGTACTCTCGTGTATATGCCTTTACATTCTTCGCAACTATTTT
TTCATTATGGCAATAGAGTTCATAATATTGAAGTCTCAATTGACGATATAAATAGATCATCAGAAATATTAAAATTAATA
GAAGATAAAACATCCATGAAGGGAGAAGACTGGAAAATGCAACAAGGTAGTTATTTCAATGCCCTAAAAGTTGAAAGTAA
TGTTATGTTTTTTATATTGACTTTAATTATAATAGTTGCAACATTTAATATTATTTCAAGTTTGTCTATATTGGTACAAG
ATAAAAAAGGAGCAATTGCTATAATGCGTACATTAGGTGTCACACGCGGTAGTATACTGAGAATATTTTGTATGTGTGGG
TTTTTTATAGGATTGATTGGTACATTAGTAGGTTGCATACTAGGTGTAGTATTTTCCTTAAATATTAATGGAATTAAAAA
CATACTAGAGAGTATCAGTCACAATAATATTTTTGATCCTATAGTTTATTTTTTTGATACCTTACCCTCCATCTTACTGG
TAAAGGACATAGTAAAGATATCATTATTATCATTGTTTTTATCATTAGTTGCAGCTATTCTTCCTGCTAGGAAAGCTGCC
TGTCAAGATCCAGCAGATATTCTACGACATGAATAG

Upstream 100 bases:

>100_bases
CAGATATTAACATTTCAGTAATAAAATTCTTGAATATCATTACTAGTAACAATGAGTAAATAATATTATTCTTTTCTATA
ATTTAATCGGATGTATTTGC

Downstream 100 bases:

>100_bases
GTAATTATATGGTGGCAAGAGAAGTATGGGGGTGGTTCTTTATGATGTTAATAACTGCTTCCTGTTCCGTGATTGCAATT
TTCTCCTATCTTGATATTAA

Product: lipoprotein releasing system transmembrane protein lolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLFKFELMLALRYLQSNRSQFLCSMITMLSFIGITLGVATLIIVMSVMNGFGEKLLNCIVGVNGQVAIYFNNNEKDTNYH
DVAKLIKDIPGVIDAIPITENQAMAKSEQSVSGIIVRGISKQDLLRKNIIADNIVRGNISDLDNGIVIGIKLAEILNVNY
GDKITILSSDSIPTVIGSIPRMKSYKVIAVFDLGMYEYDSTLVYMPLHSSQLFFHYGNRVHNIEVSIDDINRSSEILKLI
EDKTSMKGEDWKMQQGSYFNALKVESNVMFFILTLIIIVATFNIISSLSILVQDKKGAIAIMRTLGVTRGSILRIFCMCG
FFIGLIGTLVGCILGVVFSLNINGIKNILESISHNNIFDPIVYFFDTLPSILLVKDIVKISLLSLFLSLVAAILPARKAA
CQDPADILRHE

Sequences:

>Translated_411_residues
MLFKFELMLALRYLQSNRSQFLCSMITMLSFIGITLGVATLIIVMSVMNGFGEKLLNCIVGVNGQVAIYFNNNEKDTNYH
DVAKLIKDIPGVIDAIPITENQAMAKSEQSVSGIIVRGISKQDLLRKNIIADNIVRGNISDLDNGIVIGIKLAEILNVNY
GDKITILSSDSIPTVIGSIPRMKSYKVIAVFDLGMYEYDSTLVYMPLHSSQLFFHYGNRVHNIEVSIDDINRSSEILKLI
EDKTSMKGEDWKMQQGSYFNALKVESNVMFFILTLIIIVATFNIISSLSILVQDKKGAIAIMRTLGVTRGSILRIFCMCG
FFIGLIGTLVGCILGVVFSLNINGIKNILESISHNNIFDPIVYFFDTLPSILLVKDIVKISLLSLFLSLVAAILPARKAA
CQDPADILRHE
>Mature_411_residues
MLFKFELMLALRYLQSNRSQFLCSMITMLSFIGITLGVATLIIVMSVMNGFGEKLLNCIVGVNGQVAIYFNNNEKDTNYH
DVAKLIKDIPGVIDAIPITENQAMAKSEQSVSGIIVRGISKQDLLRKNIIADNIVRGNISDLDNGIVIGIKLAEILNVNY
GDKITILSSDSIPTVIGSIPRMKSYKVIAVFDLGMYEYDSTLVYMPLHSSQLFFHYGNRVHNIEVSIDDINRSSEILKLI
EDKTSMKGEDWKMQQGSYFNALKVESNVMFFILTLIIIVATFNIISSLSILVQDKKGAIAIMRTLGVTRGSILRIFCMCG
FFIGLIGTLVGCILGVVFSLNINGIKNILESISHNNIFDPIVYFFDTLPSILLVKDIVKISLLSLFLSLVAAILPARKAA
CQDPADILRHE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=422, Percent_Identity=30.3317535545024, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1787360, Length=418, Percent_Identity=29.9043062200957, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45550; Mature: 45550

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKFELMLALRYLQSNRSQFLCSMITMLSFIGITLGVATLIIVMSVMNGFGEKLLNCIV
CEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVNGQVAIYFNNNEKDTNYHDVAKLIKDIPGVIDAIPITENQAMAKSEQSVSGIIVRGIS
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHCCCCCEEECCC
KQDLLRKNIIADNIVRGNISDLDNGIVIGIKLAEILNVNYGDKITILSSDSIPTVIGSIP
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHCCCCCCEEEEEECCCCCHHHHCCC
RMKSYKVIAVFDLGMYEYDSTLVYMPLHSSQLFFHYGNRVHNIEVSIDDINRSSEILKLI
CCCCEEEEEEEECCCEEECCEEEEEECCCCEEEEEECCEEEEEEEEEECCCCHHHHHHHH
EDKTSMKGEDWKMQQGSYFNALKVESNVMFFILTLIIIVATFNIISSLSILVQDKKGAIA
HHHHCCCCCCCEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHH
IMRTLGVTRGSILRIFCMCGFFIGLIGTLVGCILGVVFSLNINGIKNILESISHNNIFDP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHH
IVYFFDTLPSILLVKDIVKISLLSLFLSLVAAILPARKAACQDPADILRHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
>Mature Secondary Structure
MLFKFELMLALRYLQSNRSQFLCSMITMLSFIGITLGVATLIIVMSVMNGFGEKLLNCIV
CEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVNGQVAIYFNNNEKDTNYHDVAKLIKDIPGVIDAIPITENQAMAKSEQSVSGIIVRGIS
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHCCCCCEEECCC
KQDLLRKNIIADNIVRGNISDLDNGIVIGIKLAEILNVNYGDKITILSSDSIPTVIGSIP
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHCCCCCCEEEEEECCCCCHHHHCCC
RMKSYKVIAVFDLGMYEYDSTLVYMPLHSSQLFFHYGNRVHNIEVSIDDINRSSEILKLI
CCCCEEEEEEEECCCEEECCEEEEEECCCCEEEEEECCEEEEEEEEEECCCCHHHHHHHH
EDKTSMKGEDWKMQQGSYFNALKVESNVMFFILTLIIIVATFNIISSLSILVQDKKGAIA
HHHHCCCCCCCEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHH
IMRTLGVTRGSILRIFCMCGFFIGLIGTLVGCILGVVFSLNINGIKNILESISHNNIFDP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHH
IVYFFDTLPSILLVKDIVKISLLSLFLSLVAAILPARKAACQDPADILRHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]