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The map label for this gene is atpA

Identifier: 58616801

GI number: 58616801

Start: 121540

End: 123063

Strand: Reverse

Name: atpA

Synonym: ERGA_CDS_00740

Alternate gene names: 58616801

Gene position: 123063-121540 (Counterclockwise)

Preceding gene: 58616802

Following gene: 58616800

Centisome position: 8.2

GC content: 34.06

Gene sequence:

>1524_bases
ATGATATCTGCGGGTGAAGTGTTAAAGGTTATTAAGGAACGTATCGAGAATTTTGATGGTCAGGTAAAATGTGAAAGTGT
TGGCGAAGTTATATCTGTCAAAGATGGTATAGCATTAGTATATGGCCTGGAAAAAGCCAAGTTTGGAGAAGTAGTAGCTT
TTGCTAATGGTACAATAGGAGTAGTATTAAATTTAGACTGCGATACTGTAAGTATAGTAATTTTTGGAAGTGAAAATAGT
GTTGGAGAAGGTGACATTGTAAAATGTACTAATCAATTAATGGATGTTCCTGTTGGGTTAGAGCTTTTAGGACGGGTAGT
TGACGCATTAGGTAATCCTATTGATGGGCTTGAGAATTTTGACACTAAAACTAGATTACCTGTAGAAATTAAAGCACCAG
GTATCATAGATAGGCAATCTGTAACTGAACCATTACAAACTGGTATTAAAGTAATAGATATGTTAATACCAATAGGACGT
GGGCAGCGTGAGTTGATTATCGGAGATAGAAAAACTGGAAAAACTGCTATAGCTATTGATACTATTATCAATCAGAAATC
CCATAACAACGAAGTAATAGATAAAGAAAAGGTTTATTGTATTTATGTTGCAATTGGACAGAAGAATTCTTCTGTAGCAA
GGATAATCAACAAATTACGTGAAAGTGGTGCACTAGAGTACACAATTGTTGTTGTTGCAGGAGCATCAGATTCTGCATCA
CTACAATATTTAGCTCCATATACTGCATGTGCTATGGGAGAATTTTTTCGAGATAATGGTATGCATTGTTTAATTGTATA
TGATGATTTATCAAAGCATGCCGCTGCATATAGGCAAATGTCCTTATTATTAAGACGTCCTCCAGGTCGTGAAGCATATC
CAGGTGATGTGTTCTTTCTACACTCTCGACTATTAGAAAGAGCAGCAAAAATGTCAGATAAGAAAGGGGGTGGCTCATTA
ACTGCTTTGCCAATTATTGAAACTCAAGCAGGTGATGTTTCAGCATATGTACCAACCAATGTAATTTCAATTACTGATGG
GCAAATTTTTCTTGAATCTGAAATTTTTTATAAAGGTCTACGTCCTGCTGTAAATGTTGGTTTATCTGTTTCTCGTGTAG
GTTCTTCTGCTCAAATTAAATCTGTAAAAAAAGTTGCAGGTTCTATAAAACTAAGTTTAGCACAGTATAGAGAATTAGAA
GATTTTGCAAAATTTGGTTCTGACGTTGATGTGCATTCTCAAAAAATTCTTGATCGTGGTAGAAGAATGATGGAGCTATT
AAAACAAAAACAATACTCTCCATTATCTGTAGGAGAACAAGTAGCCGTTATATTTGCTGGAACAAGTGGCTACTTAGATG
ACATTAGTGTTAATGATATTAGTAAGTTTGAAGAGAGACTTTTAAGTGAATTAAATAGCAATTATCCAGATATTTTAAGT
AGTATATCTAATAATAATTTTACTGATGACATCAGGTCTTTATTGTCAAAAGTTATAAGTAAGATTGCTTCTAGCTTAAA
GTAA

Upstream 100 bases:

>100_bases
GTTTTGACATAATTGACGTATCATTAAATAGTTATTTACAAAGTTTACAGGAACTCAGTAAAATAGCGGTACGTAGTATG
GTGAATAGCAAGGTGTAATA

Downstream 100 bases:

>100_bases
TTCTTTATAATTTTAGAATTTAGGTATGGATTATGAATGACTATATGAATGAAAGATTCCCTATTACAAAGGCTGGATTT
GAAAAGCTTGAACTAGAGCT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MISAGEVLKVIKERIENFDGQVKCESVGEVISVKDGIALVYGLEKAKFGEVVAFANGTIGVVLNLDCDTVSIVIFGSENS
VGEGDIVKCTNQLMDVPVGLELLGRVVDALGNPIDGLENFDTKTRLPVEIKAPGIIDRQSVTEPLQTGIKVIDMLIPIGR
GQRELIIGDRKTGKTAIAIDTIINQKSHNNEVIDKEKVYCIYVAIGQKNSSVARIINKLRESGALEYTIVVVAGASDSAS
LQYLAPYTACAMGEFFRDNGMHCLIVYDDLSKHAAAYRQMSLLLRRPPGREAYPGDVFFLHSRLLERAAKMSDKKGGGSL
TALPIIETQAGDVSAYVPTNVISITDGQIFLESEIFYKGLRPAVNVGLSVSRVGSSAQIKSVKKVAGSIKLSLAQYRELE
DFAKFGSDVDVHSQKILDRGRRMMELLKQKQYSPLSVGEQVAVIFAGTSGYLDDISVNDISKFEERLLSELNSNYPDILS
SISNNNFTDDIRSLLSKVISKIASSLK

Sequences:

>Translated_507_residues
MISAGEVLKVIKERIENFDGQVKCESVGEVISVKDGIALVYGLEKAKFGEVVAFANGTIGVVLNLDCDTVSIVIFGSENS
VGEGDIVKCTNQLMDVPVGLELLGRVVDALGNPIDGLENFDTKTRLPVEIKAPGIIDRQSVTEPLQTGIKVIDMLIPIGR
GQRELIIGDRKTGKTAIAIDTIINQKSHNNEVIDKEKVYCIYVAIGQKNSSVARIINKLRESGALEYTIVVVAGASDSAS
LQYLAPYTACAMGEFFRDNGMHCLIVYDDLSKHAAAYRQMSLLLRRPPGREAYPGDVFFLHSRLLERAAKMSDKKGGGSL
TALPIIETQAGDVSAYVPTNVISITDGQIFLESEIFYKGLRPAVNVGLSVSRVGSSAQIKSVKKVAGSIKLSLAQYRELE
DFAKFGSDVDVHSQKILDRGRRMMELLKQKQYSPLSVGEQVAVIFAGTSGYLDDISVNDISKFEERLLSELNSNYPDILS
SISNNNFTDDIRSLLSKVISKIASSLK
>Mature_507_residues
MISAGEVLKVIKERIENFDGQVKCESVGEVISVKDGIALVYGLEKAKFGEVVAFANGTIGVVLNLDCDTVSIVIFGSENS
VGEGDIVKCTNQLMDVPVGLELLGRVVDALGNPIDGLENFDTKTRLPVEIKAPGIIDRQSVTEPLQTGIKVIDMLIPIGR
GQRELIIGDRKTGKTAIAIDTIINQKSHNNEVIDKEKVYCIYVAIGQKNSSVARIINKLRESGALEYTIVVVAGASDSAS
LQYLAPYTACAMGEFFRDNGMHCLIVYDDLSKHAAAYRQMSLLLRRPPGREAYPGDVFFLHSRLLERAAKMSDKKGGGSL
TALPIIETQAGDVSAYVPTNVISITDGQIFLESEIFYKGLRPAVNVGLSVSRVGSSAQIKSVKKVAGSIKLSLAQYRELE
DFAKFGSDVDVHSQKILDRGRRMMELLKQKQYSPLSVGEQVAVIFAGTSGYLDDISVNDISKFEERLLSELNSNYPDILS
SISNNNFTDDIRSLLSKVISKIASSLK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=477, Percent_Identity=64.3605870020964, Blast_Score=635, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=477, Percent_Identity=64.3605870020964, Blast_Score=635, Evalue=0.0,
Organism=Homo sapiens, GI32189394, Length=424, Percent_Identity=27.122641509434, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913426, Length=364, Percent_Identity=25.5494505494505, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19913428, Length=299, Percent_Identity=26.7558528428094, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI19913424, Length=272, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790172, Length=516, Percent_Identity=52.3255813953488, Blast_Score=536, Evalue=1e-154,
Organism=Escherichia coli, GI1788251, Length=303, Percent_Identity=28.3828382838284, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790170, Length=384, Percent_Identity=24.4791666666667, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=480, Percent_Identity=63.75, Blast_Score=635, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=480, Percent_Identity=63.75, Blast_Score=634, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=480, Percent_Identity=59.1666666666667, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17510931, Length=376, Percent_Identity=26.3297872340426, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=362, Percent_Identity=24.8618784530387, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=395, Percent_Identity=26.0759493670886, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=64.7058823529412, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=90, Percent_Identity=38.8888888888889, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565854, Length=271, Percent_Identity=23.9852398523985, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=477, Percent_Identity=60.7966457023061, Blast_Score=615, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6319603, Length=350, Percent_Identity=28.8571428571429, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=403, Percent_Identity=26.7990074441687, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=60.1980198019802, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI281361666, Length=344, Percent_Identity=27.6162790697674, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646341, Length=344, Percent_Identity=27.6162790697674, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17136796, Length=344, Percent_Identity=27.6162790697674, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24638766, Length=403, Percent_Identity=26.302729528536, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28574560, Length=435, Percent_Identity=26.8965517241379, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583988, Length=264, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583986, Length=264, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583984, Length=264, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583992, Length=264, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129479, Length=263, Percent_Identity=26.9961977186312, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_EHRRG (Q5FF66)

Other databases:

- EMBL:   CR925677
- RefSeq:   YP_196000.1
- ProteinModelPortal:   Q5FF66
- SMR:   Q5FF66
- STRING:   Q5FF66
- GeneID:   3268237
- GenomeReviews:   CR925677_GR
- KEGG:   erg:ERGA_CDS_00740
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   ERUM302409:ERGA_CDS_00740-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55135; Mature: 55135

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00152 ATPASE_ALPHA_BETA; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAGEVLKVIKERIENFDGQVKCESVGEVISVKDGIALVYGLEKAKFGEVVAFANGTIG
CCCHHHHHHHHHHHHHCCCCEEEEHHHCCEEECCCCEEEEEECCCCCCCCEEEEECCCEE
VVLNLDCDTVSIVIFGSENSVGEGDIVKCTNQLMDVPVGLELLGRVVDALGNPIDGLENF
EEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
DTKTRLPVEIKAPGIIDRQSVTEPLQTGIKVIDMLIPIGRGQRELIIGDRKTGKTAIAID
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEH
TIINQKSHNNEVIDKEKVYCIYVAIGQKNSSVARIINKLRESGALEYTIVVVAGASDSAS
HHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
LQYLAPYTACAMGEFFRDNGMHCLIVYDDLSKHAAAYRQMSLLLRRPPGREAYPGDVFFL
EEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
HSRLLERAAKMSDKKGGGSLTALPIIETQAGDVSAYVPTNVISITDGQIFLESEIFYKGL
HHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCCEEEEHHHHHHCC
RPAVNVGLSVSRVGSSAQIKSVKKVAGSIKLSLAQYRELEDFAKFGSDVDVHSQKILDRG
CHHHHCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RRMMELLKQKQYSPLSVGEQVAVIFAGTSGYLDDISVNDISKFEERLLSELNSNYPDILS
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
SISNNNFTDDIRSLLSKVISKIASSLK
HHCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISAGEVLKVIKERIENFDGQVKCESVGEVISVKDGIALVYGLEKAKFGEVVAFANGTIG
CCCHHHHHHHHHHHHHCCCCEEEEHHHCCEEECCCCEEEEEECCCCCCCCEEEEECCCEE
VVLNLDCDTVSIVIFGSENSVGEGDIVKCTNQLMDVPVGLELLGRVVDALGNPIDGLENF
EEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
DTKTRLPVEIKAPGIIDRQSVTEPLQTGIKVIDMLIPIGRGQRELIIGDRKTGKTAIAID
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEH
TIINQKSHNNEVIDKEKVYCIYVAIGQKNSSVARIINKLRESGALEYTIVVVAGASDSAS
HHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
LQYLAPYTACAMGEFFRDNGMHCLIVYDDLSKHAAAYRQMSLLLRRPPGREAYPGDVFFL
EEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
HSRLLERAAKMSDKKGGGSLTALPIIETQAGDVSAYVPTNVISITDGQIFLESEIFYKGL
HHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCCEEEEHHHHHHCC
RPAVNVGLSVSRVGSSAQIKSVKKVAGSIKLSLAQYRELEDFAKFGSDVDVHSQKILDRG
CHHHHCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RRMMELLKQKQYSPLSVGEQVAVIFAGTSGYLDDISVNDISKFEERLLSELNSNYPDILS
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
SISNNNFTDDIRSLLSKVISKIASSLK
HHCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA