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The map label for this gene is sirB [H]

Identifier: 57652461

GI number: 57652461

Start: 111427

End: 112422

Strand: Reverse

Name: sirB [H]

Synonym: SACOL0098

Alternate gene names: 57652461

Gene position: 112422-111427 (Counterclockwise)

Preceding gene: 57652462

Following gene: 57652460

Centisome position: 4.0

GC content: 38.45

Gene sequence:

>996_bases
ATGCTACTTAAACCAAAATACCAAATCGTTATTGCTGGTTTATGTCTTGCAATAGTAGCTATCTTAAGTTTAATGATTGG
AAATACGCTTGTGTCACCAGGTACGGTGATACAGGCGTTATTCAACTTTGATAGTGAAAACGATTTACATGATGTTGTCA
CTGGTGCACGGGCGTCGAGAACAATCATTGCGTTATTGACTGGTGCTGCCCTTGCTGTCTCAGGTTTGTTGATGCAAGCA
CTTACACGAAACCCAATAGCCTCACCAGGGCTTTTCGGTGTCAATGCAGGCGCAGTATTTTTTGTCATTTTTAGTATTAC
ATTTATCCAAATTCAATCTTTTAAAATGATTGTAGTTATTGCATTTTTGGGGGCTATTGTTGTTACTGTATTAGTTGTTG
CACTAGGTATGTTTAGACAAACACTATTCTCACCTCACCGTGTCATTTTGGCAGGTGCTGCGATTGCGATGCTATTTACA
GCCTTTACTCAAGGCATACTTATTATGAACGAAACAGACTTACAAGGCCTATTATTTTGGTTAAGTGGCTCCGTTTCATT
ACGTAATATTTGGGATATCACATGGATTATTCCGCTTGTATTGATACTTATTTTAATTGCATTTAGCATGGCTGCACACA
TCAACATCTTGATGACAAGTGACGACATTGCAACCGGCCTCGGTCAAAACATAAAATTAATCAAATGGATGATTATTATG
CTCATCAGTATGTTAGCCGGTATTTCGGTAGCCGTAGCTGGATCAATCGTCTTTGTGGGTCTTATCGTACCGAATATTAG
CAAACGATTATTACCACCAAACTATAAGTATTTAATTCCTTTTACTGCATTAGCTGGAGCAATCCTAATGATCATTTCAG
ACATTGTTGCTCGTATAATAATTAAGCCACTAGAGTTGCCTATCGGTGTCGTTACCGCTGTCATTGGCGCTATTGTCTTA
ATCTATATTATGAAGAAAGGACGTCAACGCTTATGA

Upstream 100 bases:

>100_bases
GAACTTAGCTGGCGGATATAAATCTTCATTAAAACTTATTGACGATTTATATGAAAAGTTAAATATTGAAAAACAATCAA
AATAATTAAGGAGTTTTACG

Downstream 100 bases:

>100_bases
CCGAAAAGATTAATAAAAAAGACAATTACCATCTCATCTTCGCGTTAATCTTTTTAGCCATCGTTTCAGTGGTAAGTATG
ATGATTGGTTCAAGCTTTAT

Product: iron compound ABC transporter permease SirB

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MLLKPKYQIVIAGLCLAIVAILSLMIGNTLVSPGTVIQALFNFDSENDLHDVVTGARASRTIIALLTGAALAVSGLLMQA
LTRNPIASPGLFGVNAGAVFFVIFSITFIQIQSFKMIVVIAFLGAIVVTVLVVALGMFRQTLFSPHRVILAGAAIAMLFT
AFTQGILIMNETDLQGLLFWLSGSVSLRNIWDITWIIPLVLILILIAFSMAAHINILMTSDDIATGLGQNIKLIKWMIIM
LISMLAGISVAVAGSIVFVGLIVPNISKRLLPPNYKYLIPFTALAGAILMIISDIVARIIIKPLELPIGVVTAVIGAIVL
IYIMKKGRQRL

Sequences:

>Translated_331_residues
MLLKPKYQIVIAGLCLAIVAILSLMIGNTLVSPGTVIQALFNFDSENDLHDVVTGARASRTIIALLTGAALAVSGLLMQA
LTRNPIASPGLFGVNAGAVFFVIFSITFIQIQSFKMIVVIAFLGAIVVTVLVVALGMFRQTLFSPHRVILAGAAIAMLFT
AFTQGILIMNETDLQGLLFWLSGSVSLRNIWDITWIIPLVLILILIAFSMAAHINILMTSDDIATGLGQNIKLIKWMIIM
LISMLAGISVAVAGSIVFVGLIVPNISKRLLPPNYKYLIPFTALAGAILMIISDIVARIIIKPLELPIGVVTAVIGAIVL
IYIMKKGRQRL
>Mature_331_residues
MLLKPKYQIVIAGLCLAIVAILSLMIGNTLVSPGTVIQALFNFDSENDLHDVVTGARASRTIIALLTGAALAVSGLLMQA
LTRNPIASPGLFGVNAGAVFFVIFSITFIQIQSFKMIVVIAFLGAIVVTVLVVALGMFRQTLFSPHRVILAGAAIAMLFT
AFTQGILIMNETDLQGLLFWLSGSVSLRNIWDITWIIPLVLILILIAFSMAAHINILMTSDDIATGLGQNIKLIKWMIIM
LISMLAGISVAVAGSIVFVGLIVPNISKRLLPPNYKYLIPFTALAGAILMIISDIVARIIIKPLELPIGVVTAVIGAIVL
IYIMKKGRQRL

Specific function: Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=304, Percent_Identity=35.1973684210526, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790740, Length=316, Percent_Identity=31.6455696202532, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790741, Length=327, Percent_Identity=30.8868501529052, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788004, Length=308, Percent_Identity=34.7402597402597, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786347, Length=291, Percent_Identity=28.8659793814433, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786804, Length=321, Percent_Identity=29.9065420560748, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35530; Mature: 35530

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKPKYQIVIAGLCLAIVAILSLMIGNTLVSPGTVIQALFNFDSENDLHDVVTGARASR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHCCHHHH
TIIALLTGAALAVSGLLMQALTRNPIASPGLFGVNAGAVFFVIFSITFIQIQSFKMIVVI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AFLGAIVVTVLVVALGMFRQTLFSPHRVILAGAAIAMLFTAFTQGILIMNETDLQGLLFW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHH
LSGSVSLRNIWDITWIIPLVLILILIAFSMAAHINILMTSDDIATGLGQNIKLIKWMIIM
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHCCCCCHHHHHHHHHH
LISMLAGISVAVAGSIVFVGLIVPNISKRLLPPNYKYLIPFTALAGAILMIISDIVARII
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
IKPLELPIGVVTAVIGAIVLIYIMKKGRQRL
HHHHHCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLKPKYQIVIAGLCLAIVAILSLMIGNTLVSPGTVIQALFNFDSENDLHDVVTGARASR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHCCHHHH
TIIALLTGAALAVSGLLMQALTRNPIASPGLFGVNAGAVFFVIFSITFIQIQSFKMIVVI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AFLGAIVVTVLVVALGMFRQTLFSPHRVILAGAAIAMLFTAFTQGILIMNETDLQGLLFW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHH
LSGSVSLRNIWDITWIIPLVLILILIAFSMAAHINILMTSDDIATGLGQNIKLIKWMIIM
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHCCCCCHHHHHHHHHH
LISMLAGISVAVAGSIVFVGLIVPNISKRLLPPNYKYLIPFTALAGAILMIISDIVARII
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
IKPLELPIGVVTAVIGAIVLIYIMKKGRQRL
HHHHHCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8596459 [H]