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The map label for this gene is mqo2

Identifier: 57652342

GI number: 57652342

Start: 2680806

End: 2682302

Strand: Reverse

Name: mqo2

Synonym: SACOL2623

Alternate gene names: 57652342

Gene position: 2682302-2680806 (Counterclockwise)

Preceding gene: 57652343

Following gene: 57652339

Centisome position: 95.48

GC content: 36.27

Gene sequence:

>1497_bases
ATGGCTAAGTCTAATAGTAAAGACATCGTTTTAATTGGAGCCGGTGTACTTAGCACAACATTTGGTTCAATGTTAAAAGA
AATTGAGCCAGACTGGAATATCCACGTTTACGAACGCTTGGATCGTCCTGCAATCGAAAGTTCAAACGAAAGAAATAATG
CTGGTACGGGTCATGCAGCATTATGTGAGTTGAACTACACAGTTTTACAACCTGATGGTTCTATCGACATCGAAAAAGCG
AAAGTGATTAACGAAGAGTTTGAGATTTCAAAACAATTCTGGGGTCACTTAGTGAAAAGCGGTAGCATCGAGAACCCAAG
AGAATTTATCAATCCATTACCACACATCAGTTATGTTAGAGGTAAAAACAATGTTAAATTCTTAAAAGATCGTTACGAAG
CGATGAAAGCTTTCCCTATGTTCGATAATATCGAATATACTGAAGACATCGAAGTAATGAAAAAATGGATTCCATTGATG
ATGAAAGGCCGTGAAGATAACCCTGGTATCATGGCGGCAAGTAAAATTGACGAAGGTACAGATGTAAACTTCGGTGAATT
AACACGTAAAATGGCTAAAAGCATTGAAGCACATCCAAATGCTACAGTGCAATTTAACCATGAAGTTGTTGATTTTGAAC
AATTATCAAATGGTCAATGGGAAGTTACTGTTAAAAATCGCCTAACTGGTGAGAAATTCAAACAAGTAACTGACTACGTA
TTCATCGGTGCTGGCGGTGGAGCAATTCCATTATTACAAAAAACAGGTATCCCTGAAAGTAAACATTTGGGTGGATTCCC
TATCAGTGGTCAATTCTTAGCTTGTACAAACCCACAAGTTATTGAACAACACGATGCCAAAGTTTATGGTAAAGAGCCAC
CTGGTACACCACCAATGACTGTACCTCATTTAGATACGCGTTACATTGATGGTCAAAGAACATTATTATTTGGACCATTT
GCTAATGTTGGACCTAAATTCTTGAAAAATGGTTCTAACTTAGATTTATTCAAGTCTGTTAAAACATACAACATTACAAC
TTTATTAGCAGCAGCAGTTAAAAACTTACCTTTAATTAAATACTCATTTGACCAAGTAATTATGACAAAAGAAGGTTGTA
TGAACCACTTACGTACTTTCTATCCAGAAGCACGTAATGAAGATTGGCAATTATACACTGCTGGTAAACGTGTACAAGTT
ATCAAAGATACACCTGAACACGGTAAAGGATTCATCCAATTCGGTACAGAAGTGGTTAACTCACAAGACCACACTGTAAT
TGCATTATTAGGTGAATCACCAGGGGCTTCAACTTCAGTTTCAGTTGCGTTAGAAGTATTAGAACGTAACTTCCCTGAAT
ACAAAACTGAATGGGCACCTAAAATTAAGAAAATGATTCCATCATACGGTGAATCATTAATTGAAGACGAAAAATTAATG
AGAAAAATCCGTAAACAAACTTCAAAAGACTTAGAATTAGGTTACTACGAAAACTAA

Upstream 100 bases:

>100_bases
GGAAGTTATCAATGGCGTTGATATTTTAAAGAAATATGTCAGTTTTATGTAACTTTCATATTGATGATACACATTTACAA
TTTTTGGAGAGGTGAAACCA

Downstream 100 bases:

>100_bases
ATTCTAATAGCTATATTTAAAATCGGACAACTGAGAAATCTTAAAGATTTTTCAGCTGTCCGATTTTTTTACGTAATCTA
ATACATACGGCAAAATCAAC

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO 2; Malate dehydrogenase [quinone] 2

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAALCELNYTVLQPDGSIDIEKA
KVINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVRGKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLM
MKGREDNPGIMAASKIDEGTDVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYV
FIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMTVPHLDTRYIDGQRTLLFGPF
ANVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIKYSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQV
IKDTPEHGKGFIQFGTEVVNSQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLM
RKIRKQTSKDLELGYYEN

Sequences:

>Translated_498_residues
MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAALCELNYTVLQPDGSIDIEKA
KVINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVRGKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLM
MKGREDNPGIMAASKIDEGTDVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYV
FIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMTVPHLDTRYIDGQRTLLFGPF
ANVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIKYSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQV
IKDTPEHGKGFIQFGTEVVNSQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLM
RKIRKQTSKDLELGYYEN
>Mature_497_residues
AKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAALCELNYTVLQPDGSIDIEKAK
VINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVRGKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLMM
KGREDNPGIMAASKIDEGTDVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYVF
IGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMTVPHLDTRYIDGQRTLLFGPFA
NVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIKYSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQVI
KDTPEHGKGFIQFGTEVVNSQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLMR
KIRKQTSKDLELGYYEN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=490, Percent_Identity=46.3265306122449, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO2_STAAC (Q5HCU5)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_187412.1
- ProteinModelPortal:   Q5HCU5
- STRING:   Q5HCU5
- EnsemblBacteria:   EBSTAT00000009622
- GeneID:   3237074
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL2623
- TIGR:   SACOL2623
- eggNOG:   COG0579
- GeneTree:   EBGT00050000024300
- HOGENOM:   HBG289663
- OMA:   NSEDHSV
- ProtClustDB:   PRK13339
- BioCyc:   SAUR93062:SACOL2623-MONOMER
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 56000; Mature: 55868

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAA
CCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCEEHHHHCCCCCCCCCCCCCCCCCCCEE
LCELNYTVLQPDGSIDIEKAKVINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVR
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEE
GKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLMMKGREDNPGIMAASKIDEGT
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
DVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYV
CCCHHHHHHHHHHHHHCCCCCEEEECCEEEEHHHHCCCEEEEEECCCCCHHHHHHHHCEE
FIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMT
EEECCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCEEECCCCCCCCCCC
VPHLDTRYIDGQRTLLFGPFANVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIK
CCCCCCEEECCCEEEEECCCHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
YSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQVIKDTPEHGKGFIQFGTEVVN
EEHHHHEECHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCEEECHHHHC
SQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLM
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKIRKQTSKDLELGYYEN
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAA
CCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCEEHHHHCCCCCCCCCCCCCCCCCCCEE
LCELNYTVLQPDGSIDIEKAKVINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVR
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEE
GKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLMMKGREDNPGIMAASKIDEGT
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
DVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYV
CCCHHHHHHHHHHHHHCCCCCEEEECCEEEEHHHHCCCEEEEEECCCCCHHHHHHHHCEE
FIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMT
EEECCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCEEECCCCCCCCCCC
VPHLDTRYIDGQRTLLFGPFANVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIK
CCCCCCEEECCCEEEEECCCHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
YSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQVIKDTPEHGKGFIQFGTEVVN
EEHHHHEECHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCEEECHHHHC
SQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLM
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKIRKQTSKDLELGYYEN
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA