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The map label for this gene is isaA [H]

Identifier: 57652306

GI number: 57652306

Start: 2648751

End: 2649452

Strand: Reverse

Name: isaA [H]

Synonym: SACOL2584

Alternate gene names: 57652306

Gene position: 2649452-2648751 (Counterclockwise)

Preceding gene: 57652307

Following gene: 57652305

Centisome position: 94.31

GC content: 41.6

Gene sequence:

>702_bases
ATGAAAAAGACAATTATGGCATCATCATTAGCAGTGGCATTAGGTGTAACAGGTTACGCAGCAGGTACAGGACATCAAGC
ACACGCTGCTGAAGTAAACGTTGATCAAGCACACTTAGTTGACTTAGCGCATAATCACCAAGATCAATTAAATGCAGCTC
CAATCAAAGATGGTGCATATGACATCCACTTTGTAAAAGATGGTTTCCAATATAACTTCACTTCAAATGGTACTACATGG
TCATGGAGCTATGAAGCAGCTAATGGTCAAACTGCTGGTTTCTCAAACGTTGCAGGTGCAGACTACACTACTTCATACAA
CCAAGGTTCAAATGTACAATCAGTAAGCTACAATGCACAATCAAGTAACTCAAACGTTGAAGCTGTTTCAGCTCCAACTT
ACCATAACTACAGCACTTCAACTACTTCAAGTTCAGTGAGATTAAGCAATGGTAATACTGCAGGTGCTACTGGTTCATCA
GCAGCTCAAATCATGGCTCAACGTACTGGTGTTTCAGCTTCTACATGGGCTGCAATCATCGCTCGTGAATCAAATGGTCA
AGTAAATGCTTACAACCCATCAGGTGCTTCAGGTTTATTCCAAACTATGCCAGGTTGGGGTCCAACAAACACTGTTGACC
AACAAATCAACGCAGCTGTTAAAGCATACAAAGCACAAGGTTTAGGTGCTTGGGGATTCTAA

Upstream 100 bases:

>100_bases
AAGAAATAAAAGACAATTTAAACTTGCACTACGACATTCAAATTCAAAATATAATTACTAAAAACATAAACTTACAATTA
TTACTGGAGGATTTTTTACT

Downstream 100 bases:

>100_bases
TTCCTTCATAATAAATAAAAGTAATGTTTAGACATTAAATATATAGCTCTTCCCATAGAAATTGGGGAGAGTTTTTTTAT
TAATTAAAAATACATTTTTT

Product: immunodominant antigen A

Products: NA

Alternate protein names: Immunodominant staphylococcal antigen A [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTW
SWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSS
AAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF

Sequences:

>Translated_233_residues
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTW
SWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSS
AAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>Mature_233_residues
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTW
SWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSS
AAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF

Specific function: Is able to cleave peptidoglycan [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase family. IsaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010618 [H]

Pfam domain/function: PF06737 Transglycosylas [H]

EC number: NA

Molecular weight: Translated: 24203; Mature: 24203

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAY
CCCCHHHHHHEEEHCCCEEECCCCCCCEEEECCCCHHHHHHHHHCCCHHCCCCCCCCCCE
DIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQ
EEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCC
SSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAII
CCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHEEEEE
ARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
EECCCCEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAY
CCCCHHHHHHEEEHCCCEEECCCCCCCEEEECCCCHHHHHHHHHCCCHHCCCCCCCCCCE
DIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQ
EEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCC
SSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAII
CCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHEEEEE
ARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
EECCCCEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA