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The map label for this gene is ygcA [C]

Identifier: 57652118

GI number: 57652118

Start: 2017126

End: 2018487

Strand: Reverse

Name: ygcA [C]

Synonym: SACOL1957

Alternate gene names: 57652118

Gene position: 2018487-2017126 (Counterclockwise)

Preceding gene: 57652119

Following gene: 57652117

Centisome position: 71.85

GC content: 33.11

Gene sequence:

>1362_bases
TTGCAAGCAATAGCTAAAAATGACATAAAAACGGGAACAGTTGTTGATTTAACGCATGAAGGCCATGGTGTCGTAAAAAT
AGATCGCTTTCCTATTTTCATACCACAAGCTTTAATTAATGAACAAATTGAATATAAAATTATCAAAGTAAAAAAGAACT
TTGCGATAGGTAAGTTGCTTAATATAAATACGAGAAGTGAGAATCGTGTTGCACCGCCATGTATATATTATGAACGTTGT
GGTGGGTGCCAACTTCAACACTTATCATACGAAGCACAACTTGAAATGAAAAAGGAACAAGTGATTAATTTGTTTCAGCG
AAAAGCGCATTTTGATAATTCTAAGATTAACGATACAGTTGGCATGACAGATCCTTGGAGATATCGAAACAAGTCCCAGA
TTCCAGTTGGTAAGAATGAACAGAATGAAGTTATTATGGGCTTTTATCGTCAAAGAAGCCATGACATTATTGACATGGAA
AGTTGTTTAATACAAGATTCACAACATCAAGAAGTGATGAATGAAGTTAAATCTATTTTAAAAGATTTAAATGTAAGTAT
TTATCAAGAACAATTGAAAAAAGGTTTAATGAGACATTTGGTTGTAAGAACAGGATATCATACAGACGAAATGATGATTA
TTTTTGTAACTAATGGTAAAAAGTGGCCACAAAAAAATGCTGTTGTTGAGAAGATATTAGATGCATTTCCTAATGTGACA
AGCATTAAACAAAACATTAATGATAGCCACTCTAATGTTATTATGGGACGTCAATCTATAACGCTATATGGTAAAGATAC
AATTATTGATCAATTAACAGATAGTACATTTAAAATAAGTGATCAGTCATTCTACCAAATTAATTCTGAACAAACAGAGA
AATTATATAATAAAGCAATTGAGTATGCGCAATTGACAGGTAATGAAGTTGTATTAGATACCTATTGTGGTATTGGAACA
ATAGGGCTATATATGGCACCACTTGCAAAACATGTATACGGTGTTGAAGTAGTACCTTCTGCAATTGAAGACGCACAACA
AAATGCGACTATAAACCAATGCAATAATACAACTTTTGTCTGTGGGAAAGCTGAAGAAGTTATTTTACAATGGAAAGCAC
AAGGGATTAAACCAGATGTTGTAATGGTTGATCCGCCAAGAAAGGGCTGTGACGAAACGTTTATTCAGACTTTGCTTACA
TTAGAACCTAAGCGTATTGTCTATATTTCATGTAATCCCGCAACACAGCAACGTGATGCATTATTATTAGCTGAAAAATA
TCAACTTGAAGAGGTAACACCGGTAGATATGTTTCCACAAACAACACATGTTGAGACAGTGGCATTATTCAATTTGAAAT
AG

Upstream 100 bases:

>100_bases
ACAATTTAATCGAAGAATAAACAGAAATAGTGAAATATATAATGGCAGGTTAGGAAGCGCATAATTTTGTTCCTAACCTG
TTCATTTTGGAGGTAAAATT

Downstream 100 bases:

>100_bases
CGCACATGATTTGAGATAAAATTTCGCCTTAATAAGTGAAGAAAGAAGTCGTATATTAAAATTTTATTACAGCCAATTTA
CTTTCTTGATATGAACTTTT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK

Sequences:

>Translated_453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>Mature_453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=350, Percent_Identity=28.2857142857143, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI51173878, Length=350, Percent_Identity=28.2857142857143, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI269784678, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI269784680, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI269784676, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI20149688, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=9e-26,
Organism=Escherichia coli, GI1789148, Length=449, Percent_Identity=31.4031180400891, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1787083, Length=380, Percent_Identity=25.2631578947368, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1790403, Length=208, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997438, Length=164, Percent_Identity=32.3170731707317, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322909, Length=448, Percent_Identity=23.2142857142857, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24666579, Length=415, Percent_Identity=29.1566265060241, Blast_Score=151, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 51683; Mature: 51683

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
CCCCCCCCCCCCCEEEEEECCCCEEEECCCCEECCHHHHCCCCEEEEEEEECCCCEEEEE
NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
ECCCCCCCCCCCCEEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHH
KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHH
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
HHHHHCCCCCCEEEEECCEEEEEECHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHH
EYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFV
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHCCCCCCCCCCEEE
CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
ECCHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCE
LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
EEEEHHHCCCCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
CCCCCCCCCCCCCEEEEEECCCCEEEECCCCEECCHHHHCCCCEEEEEEEECCCCEEEEE
NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
ECCCCCCCCCCCCEEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHH
KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHH
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
HHHHHCCCCCCEEEEECCEEEEEECHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHH
EYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFV
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHCCCCCCCCCCEEE
CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
ECCHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCE
LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
EEEEHHHCCCCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]