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The map label for this gene is polX [H]

Identifier: 57651752

GI number: 57651752

Start: 1161345

End: 1163057

Strand: Direct

Name: polX [H]

Synonym: SACOL1153

Alternate gene names: 57651752

Gene position: 1161345-1163057 (Clockwise)

Preceding gene: 57651751

Following gene: 57651753

Centisome position: 41.34

GC content: 32.57

Gene sequence:

>1713_bases
ATGACAAAAAAAGATGTTATCAAACTATTAGAACAAATTGCTACTTATATGGAATTAAAAGGGGAAAATACTTTTAAAAT
ATCAGCGTATCGAAAAGCAGCTCAAAGTCTTGAATTAGATGAACGACCATTAGATGAAATATCTGATGTAACGGAGTTAA
AAGGCATTGGTAAAGGTGTTGCAGAAGTAATCAATGATTACCGTGAGACCGGTGAATCTCAGTATTTACAGCAATTACAG
GAAGAAGTTCCGGAAGGTCTTATTCCACTTTTGAAAATTCAAGGACTTGGAAGCAAGAAAATTGCTAAGCTATATAAAGA
GTTGAATATTGTTGATAAAGCGTCACTTCAAGTTGCTTGTGAAAATGGAAAAGTTAGTGAATTAAGCGGATTTGCTAAGA
AAACGGAACAAAACATATTAGAAGCTGTGAAACAACTTGGTGCTAAGAAAGATAGATATCCAATTGATCAAATGAGAAGA
CTTAATCAAGAAATCATTGATTATATAGATACATTAAATTATATCGATCAATATTCATCTGCAGGAAGCTTCCGTCGTTT
TAAAGAAATGAGCAAAGATTTAGATTTCATAATAAGTACCGATAACCCAAAAGCAGTGCAGCAGCAATTATTAAATATTC
CCAATAAAGTAAAAGAAGTTGCAGTGGGGAACACAAAAGTTTCATTAGAATTAGCGTATGATGATGAAACGATTGGTGTC
GATTTTCGATTAATTGAACCAAGTGCTTTTTATCATACATTGCAGCATTTTACTGGGTCAAAAGAACATAATATAAGAAT
TCGACAACTTGCTAAAGCACGTGATGAAAAAGTAAGTGAATATGGAATTGAACAAGCTGATGGTACATTAATTCAATATG
ATAGTGAAGCCAAGATATATGAACATTTTAATGTGAATTTTATACCACCTGCTATGCGAGAAGATGGTAGCGAATTTGAT
AAAGATCTAAGTAATATCATTACAATAGATGATATTAATGGTGATATTCATATGCATACAACGTATAGTGATGGTGCGTT
TTCTATTCGAGACATGGTAGAAGCAAATATCGCAAAAGGTTATAAATTCATGGTAATTACTGATCATTCACAAAGTTTAC
GTGTTGCTAATGGCTTACAAGTAGAAAGACTTTTAAGACAAAACGAAGAAATTAAGGCTTTAGATAAAGAATATAGTGAA
ATTGATATTTATTCAGGTACAGAAATGGATATATTACCTGATGGCTCGCTGGATTATGATGATGAAATTTTAGCACAACT
TGATTATGTAATTGGAGCTATTCATCAAAGCTTTAACCAATCAGAAGAACAAATTATGGAACGATTAGCTAATGCATGTC
GCAATCCATACGTGCGACATATAGCGCATCCAACAGGGCGTATTATAGGTAGAAGAGATGGTTATAAACCGAATATTGAA
CAATTAATGGCATTAGCTGAAGAAACGAATACAGTATTAGAAATTAATGCCAATCCACATCGACTGGATCTGAGCGCTGA
TATCGTTCGTAAATATCCAAATGTGAAATTAACTATTAACACTGATGCGCATCATACAAATCATTTAGATTTTATGAATT
ATGGCGTAGCAACTGCGCAAAAAGGATTTGTAACAAAAGATAGAGTGATTAACGCATTATCGCGTGAAGCTTTTAAAGAC
TTTATTGAAAATAATACAAAACTTAAGAAATAG

Upstream 100 bases:

>100_bases
TTTATCGGCTTTCACCATTAATTTATAAATTATCATAAGAGGTCAGGACAAAGGTATATATTAATGATACGTCCTGGTCT
TCTTTTTATGGAGTGTTATT

Downstream 100 bases:

>100_bases
AGGGATTTTATGAGACAAAAAACATTAGACGTCTTAGAATTTGAAAAAATAAAATCACTCGTTGCCAATGAAACTATTAG
TGACTTAGGCTTGGAAAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MTKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPLDEISDVTELKGIGKGVAEVINDYRETGESQYLQQLQ
EEVPEGLIPLLKIQGLGSKKIAKLYKELNIVDKASLQVACENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRR
LNQEIIDYIDTLNYIDQYSSAGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVKEVAVGNTKVSLELAYDDETIGV
DFRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDEKVSEYGIEQADGTLIQYDSEAKIYEHFNVNFIPPAMREDGSEFD
KDLSNIITIDDINGDIHMHTTYSDGAFSIRDMVEANIAKGYKFMVITDHSQSLRVANGLQVERLLRQNEEIKALDKEYSE
IDIYSGTEMDILPDGSLDYDDEILAQLDYVIGAIHQSFNQSEEQIMERLANACRNPYVRHIAHPTGRIIGRRDGYKPNIE
QLMALAEETNTVLEINANPHRLDLSADIVRKYPNVKLTINTDAHHTNHLDFMNYGVATAQKGFVTKDRVINALSREAFKD
FIENNTKLKK

Sequences:

>Translated_570_residues
MTKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPLDEISDVTELKGIGKGVAEVINDYRETGESQYLQQLQ
EEVPEGLIPLLKIQGLGSKKIAKLYKELNIVDKASLQVACENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRR
LNQEIIDYIDTLNYIDQYSSAGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVKEVAVGNTKVSLELAYDDETIGV
DFRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDEKVSEYGIEQADGTLIQYDSEAKIYEHFNVNFIPPAMREDGSEFD
KDLSNIITIDDINGDIHMHTTYSDGAFSIRDMVEANIAKGYKFMVITDHSQSLRVANGLQVERLLRQNEEIKALDKEYSE
IDIYSGTEMDILPDGSLDYDDEILAQLDYVIGAIHQSFNQSEEQIMERLANACRNPYVRHIAHPTGRIIGRRDGYKPNIE
QLMALAEETNTVLEINANPHRLDLSADIVRKYPNVKLTINTDAHHTNHLDFMNYGVATAQKGFVTKDRVINALSREAFKD
FIENNTKLKK
>Mature_569_residues
TKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPLDEISDVTELKGIGKGVAEVINDYRETGESQYLQQLQE
EVPEGLIPLLKIQGLGSKKIAKLYKELNIVDKASLQVACENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRRL
NQEIIDYIDTLNYIDQYSSAGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVKEVAVGNTKVSLELAYDDETIGVD
FRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDEKVSEYGIEQADGTLIQYDSEAKIYEHFNVNFIPPAMREDGSEFDK
DLSNIITIDDINGDIHMHTTYSDGAFSIRDMVEANIAKGYKFMVITDHSQSLRVANGLQVERLLRQNEEIKALDKEYSEI
DIYSGTEMDILPDGSLDYDDEILAQLDYVIGAIHQSFNQSEEQIMERLANACRNPYVRHIAHPTGRIIGRRDGYKPNIEQ
LMALAEETNTVLEINANPHRLDLSADIVRKYPNVKLTINTDAHHTNHLDFMNYGVATAQKGFVTKDRVINALSREAFKDF
IENNTKLKK

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1796

COG function: function code L; DNA polymerase IV (family X)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

Organism=Homo sapiens, GI4505931, Length=334, Percent_Identity=22.7544910179641, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 64871; Mature: 64740

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPLDEISDVTELKGIGKGV
CCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHH
AEVINDYRETGESQYLQQLQEEVPEGLIPLLKIQGLGSKKIAKLYKELNIVDKASLQVAC
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEE
ENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRRLNQEIIDYIDTLNYIDQYSS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
AGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVKEVAVGNTKVSLELAYDDETIGV
CCHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEECCCEECE
DFRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDEKVSEYGIEQADGTLIQYDSEAKIY
EEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHH
EHFNVNFIPPAMREDGSEFDKDLSNIITIDDINGDIHMHTTYSDGAFSIRDMVEANIAKG
HCCCCCCCCCHHHCCCHHHHHHHHHEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCC
YKFMVITDHSQSLRVANGLQVERLLRQNEEIKALDKEYSEIDIYSGTEMDILPDGSLDYD
EEEEEEECCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEECCCCCCCCC
DEILAQLDYVIGAIHQSFNQSEEQIMERLANACRNPYVRHIAHPTGRIIGRRDGYKPNIE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCCHHEECCCCCCCCCHH
QLMALAEETNTVLEINANPHRLDLSADIVRKYPNVKLTINTDAHHTNHLDFMNYGVATAQ
HHHHHHHCCCCEEEECCCCCEECCCHHHHHHCCCEEEEEECCCCCCCCCHHHHCCHHHHC
KGFVTKDRVINALSREAFKDFIENNTKLKK
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPLDEISDVTELKGIGKGV
CHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHH
AEVINDYRETGESQYLQQLQEEVPEGLIPLLKIQGLGSKKIAKLYKELNIVDKASLQVAC
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEE
ENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRRLNQEIIDYIDTLNYIDQYSS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
AGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVKEVAVGNTKVSLELAYDDETIGV
CCHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEECCCEECE
DFRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDEKVSEYGIEQADGTLIQYDSEAKIY
EEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHH
EHFNVNFIPPAMREDGSEFDKDLSNIITIDDINGDIHMHTTYSDGAFSIRDMVEANIAKG
HCCCCCCCCCHHHCCCHHHHHHHHHEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCC
YKFMVITDHSQSLRVANGLQVERLLRQNEEIKALDKEYSEIDIYSGTEMDILPDGSLDYD
EEEEEEECCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEECCCCCCCCC
DEILAQLDYVIGAIHQSFNQSEEQIMERLANACRNPYVRHIAHPTGRIIGRRDGYKPNIE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCCHHEECCCCCCCCCHH
QLMALAEETNTVLEINANPHRLDLSADIVRKYPNVKLTINTDAHHTNHLDFMNYGVATAQ
HHHHHHHCCCCEEEECCCCCEECCCHHHHHHCCCEEEEEECCCCCCCCCHHHHCCHHHHC
KGFVTKDRVINALSREAFKDFIENNTKLKK
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]