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The map label for this gene is isdF

Identifier: 57651743

GI number: 57651743

Start: 1151937

End: 1152902

Strand: Direct

Name: isdF

Synonym: SACOL1144

Alternate gene names: 57651743

Gene position: 1151937-1152902 (Clockwise)

Preceding gene: 57651742

Following gene: 57651744

Centisome position: 41.0

GC content: 32.71

Gene sequence:

>966_bases
ATGATAAAAAATAAAAAGAAACTACTATTTTTATGTTTGTTAGTCATTTTAATCGCAACTGCTTATATTTCGTTTGTAAC
CGGTACAATTAAATTGTCATTTAATGACCTATTTACAAAATTTACAACTGGTAGCAATGAAGCAGTGGATTCAATCATTG
ATTTGCGATTGCCACGTATATTAATTGCATTGATGGTTGGCGCAATGTTAGCAGTTTCTGGAGCATTATTACAAGCAGCA
CTACAAAATCCTTTGGCAGAGGCGAATATCATTGGCGTTTCCTCAGGTGCACTTATAATGAGAGCACTTTGTATGTTGTT
TATTCCACAATTGTACTTTTACTTACCATTATTAAGTTTTATTGGAGGTTTAATACCATTTTTAATAATTATATTGTTGC
ATTCTAAATTTAGATTCAATGCTGTAAGTATGATATTAGTAGGTGTTGCGTTATTCGTATTATTAAATGGTGTTTTAGAA
ATTTTAACTCAAAACCCTTTAATGAAAATTCCTCAAGGCTTAACAATGAAAATATGGAGCGACGTATACATATTAGCAGT
ATCAGCATTATTGGGATTAATATTAACATTACTATTGTCCCCTAAATTGAATTTACTAAATTTAGACGACATACAAGCGC
GAAGTATCGGTTTTAATATTGATCGTTACAGATGGTTAACAGGTTTATTAGCAGTATTTTTAGCAAGTGCAACTGTTGCG
ATTGTTGGACAACTAGCCTTTTTAGGTATTATTGTGCCACATGTGGTTAGAAAGCTAGTTGGGGGCAATTACAGAGTACT
TATTCCGTTTTCTACAGTTATTGGTGCATGGCTATTGTTAGTGGCTGATTTATTAGGACGAGTGATACAGCCTCCTTTAG
AAATTCCAGCCAATGCTATTTTAATGATTGTCGGTGGTCCAATGCTAATTTACTTAATTTGTCAAAGTCAACGAAATCGA
ATCTAA

Upstream 100 bases:

>100_bases
GGAAGTGCCATTCGGTATTACAGCAAATGTTGATGCTGATAAGGCAATGACTCAATTATATGATTTATTTTATAAGGATA
AAAAATAGTGAGTTGATATG

Downstream 100 bases:

>100_bases
AACGGTACAACAACTGGTTTAGTGATGACTGAAGAAACGTCGTTAATAAAAGAGGATTTTTATGAGAATGAAGCGATTTT
TAACTATTGTACAAATTTTA

Product: iron compound ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron-regulated surface determinant protein F; Staphylococcal iron-regulated protein G

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAA
LQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLE
ILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVA
IVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNR
I

Sequences:

>Translated_321_residues
MIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAA
LQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLE
ILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVA
IVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNR
I
>Mature_321_residues
MIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAA
LQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLE
ILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVA
IVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNR
I

Specific function: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily

Homologues:

Organism=Escherichia coli, GI1790740, Length=307, Percent_Identity=35.5048859934853, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790741, Length=302, Percent_Identity=32.1192052980132, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786347, Length=303, Percent_Identity=29.042904290429, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786804, Length=334, Percent_Identity=28.1437125748503, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786805, Length=294, Percent_Identity=32.312925170068, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788004, Length=282, Percent_Identity=29.7872340425532, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISDF_STAA1 (A7X154)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441715.1
- ProteinModelPortal:   A7X154
- SMR:   A7X154
- STRING:   A7X154
- EnsemblBacteria:   EBSTAT00000002742
- GeneID:   5560684
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1125
- eggNOG:   COG0609
- GeneTree:   EBGT00050000023880
- HOGENOM:   HBG700016
- ProtClustDB:   CLSK885156
- BioCyc:   SAUR418127:SAHV_1125-MONOMER
- InterPro:   IPR000522

Pfam domain/function: PF01032 FecCD

EC number: NA

Molecular weight: Translated: 35045; Mature: 35045

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdbf258c)-; HASH(0xe2bd974)-; HASH(0xdec99c8)-; HASH(0xe0fdb40)-; HASH(0xd0f3d78)-; HASH(0xdc5cc24)-; HASH(0xd228ca4)-; HASH(0xbc4b238)-; HASH(0xe2ad500)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSIIDLRLPRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHH
LIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSF
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIPQGLTMKIWS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHH
DVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVA
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
LMIVGGPMLIYLICQSQRNRI
EEEECCHHHHHHHHHHHCCCH
>Mature Secondary Structure
MIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSIIDLRLPRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHH
LIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSF
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIPQGLTMKIWS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHH
DVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVA
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
LMIVGGPMLIYLICQSQRNRI
EEEECCHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA