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The map label for this gene is purQ

Identifier: 57651677

GI number: 57651677

Start: 1085488

End: 1086159

Strand: Direct

Name: purQ

Synonym: SACOL1077

Alternate gene names: 57651677

Gene position: 1085488-1086159 (Clockwise)

Preceding gene: 57651676

Following gene: 57651678

Centisome position: 38.64

GC content: 34.82

Gene sequence:

>672_bases
ATGAAATTTGCGGTTCTTGTTTTTCCAGGTTCGAATTGTGATAGAGACATGTTTAATGCTGCTATTAAAAGTGGTGTTGA
AGCGGAATATGTAGATTATAGAGAAACATCACTAAGTGGATTTGATGGCGTACTTATTCCTGGTGGATTTTCATTCGGGG
ATTACTTAAGATCTGGGGCAATGGCTAGTGTAGCGCCGATTATTTCGGAAGTTAAACGTCTTGCAGCTGAAGGTAAGCCA
GTATTAGGTGTTTGTAATGGGTTTCAAATTTTAACTGAAATAGGCTTATTACCTGGTGCATTATTGCATAACGATTCACA
TTTATTTATTAGTAGAAATGAAGAGTTAGAAATAGTGAATAATCAAACGGCATTTACAAATCTTTATGAACAAGGTGAAA
AAGTTATATATCCTGTAGCTCACGGTGAAGGTCATTATTATTGTACTGATGAAATATATCAACAATTAAAAGCTAACAAT
CAAATTATTCTGAAATATGTGAATAATCCGAACGGTTCATATGATGATATTGCAGGAATTGTTAACGAAAAAGGCAATGT
ATGTGGCATGATGCCACATCCTGAAAGAGCTTTAGAAACGTTGTTAGGTACTGATAGTGGTGTGAAATTATTTGAAGCGA
TGGTAAAAAGTTGGAGGGAACAACATGTCTAA

Upstream 100 bases:

>100_bases
CACAACATTATTACAACTCTAAGTGAAAAATTGTTTGCAAATACAGTGATTGAAGAATATAGCTATAAAGTGTTAGATGA
TGAAAAGGAGAATGCATAAA

Downstream 100 bases:

>100_bases
ATTTATCGAACCAAGCGTTGAAGAAATTAAACTTGAAAAAGTATATCAAGATATGGGATTAAGTGATCAAGAATATGAAA
AAGTTTGCGATATTTTAGGC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKP
VLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANN
QIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV

Sequences:

>Translated_223_residues
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKP
VLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANN
QIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>Mature_223_residues
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKP
VLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANN
QIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=229, Percent_Identity=28.82096069869, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=232, Percent_Identity=29.3103448275862, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582111, Length=232, Percent_Identity=30.1724137931034, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582109, Length=232, Percent_Identity=30.1724137931034, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17137292, Length=232, Percent_Identity=30.1724137931034, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_STAA3 (Q2FI10)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_493668.1
- ProteinModelPortal:   Q2FI10
- SMR:   Q2FI10
- STRING:   Q2FI10
- EnsemblBacteria:   EBSTAT00000038365
- GeneID:   3914501
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_0970
- eggNOG:   COG0047
- GeneTree:   EBGT00050000024256
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- ProtClustDB:   PRK03619
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF00117 GATase

EC number: =6.3.5.3

Molecular weight: Translated: 24527; Mature: 24527

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 85-85 ACT_SITE 193-193 ACT_SITE 195-195

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGA
CEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEECCCCCHHHHHHCCC
MASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVN
HHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCEEECCCEEEEECCCCEEEEC
NQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGI
CCHHHHHHHHCCCEEEEEEECCCCCEEEHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
VNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
HCCCCCEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGA
CEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEECCCCCHHHHHHCCC
MASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVN
HHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCEEECCCEEEEECCCCEEEEC
NQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGI
CCHHHHHHHHCCCEEEEEEECCCCCEEEHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
VNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
HCCCCCEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA