Click here to switch to the map view.

The map label for this gene is spsB [H]

Identifier: 57651657

GI number: 57651657

Start: 971238

End: 971822

Strand: Direct

Name: spsB [H]

Synonym: SACOL0969

Alternate gene names: 57651657

Gene position: 971238-971822 (Clockwise)

Preceding gene: 57651656

Following gene: 57651658

Centisome position: 34.57

GC content: 31.28

Gene sequence:

>585_bases
GTGTCAAAATTGAAAAAAGAAATATTGGAATGGATTATTTCAATTGCAGTCGCTTTTGTCATTTTATTTATAGTAGGTAA
ATTTATTGTTACGCCATATACAATTAAAGGTGAATCAATGGATCCAACTTTGAAAGATGGCGAGCGAGTAGCTGTAAACA
TTGTTGGATATAAAACAGGTGGTTTGGAAAAAGGTAATGTAGTTGTCTTCCATGCAAACAAAAATGATGACTATGTTAAA
CGTGTCATCGGTGTTCCTGGTGATAAAGTAGAATACAAAAATGATACATTATATGTCAATGGTAAAAAACAAGATGAACC
ATATTTAAACTACAATTTAAAACATAAACAAGGTGATTACATTACTGGGACTTTCCAAGTTAAAGATTTACCGAATGCGA
ATCCTAAATCAAATGTCATTCCAAAAGGTAAATATTTAGTGCTTGGAGATAATCGTGAAGTAAGTAAAGATAGCCGTGCG
TTTGGCCTCATTGATGAAGACCAAATTGTTGGTAAAGTTTCATTTAGGTTCTGGCCATTTAGTGAATTTAAACATAATTT
CAATCCTGAAAATACTAAAAATTAA

Upstream 100 bases:

>100_bases
ACAATTTGGTTTAATCGATAAAAAGGATATTATTGGTAATGTTAGTTTACGATACTATCCTTTTTCAAAATGGACTGTTC
AGTTCAAATCTTAAAAAGAG

Downstream 100 bases:

>100_bases
TATGAAACAAATACAACATCGTTTGTCGGTTTTAATACTGATAAACGATGTTTTATTTTGTTAGTACCACAATAAAAGCT
AAGTTCGAAATGAACTTATA

Product: signal peptidase IB

Products: NA

Alternate protein names: SPase IB; Leader peptidase IB [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSKLKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVK
RVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRA
FGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN

Sequences:

>Translated_194_residues
MSKLKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVK
RVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRA
FGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>Mature_193_residues
SKLKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKR
VIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAF
GLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN

Specific function: Essential for cell viability [H]

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22006; Mature: 21875

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEEEECC
GLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDY
CCCCCCEEEEEECCCHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCEEEEEEEECCCCE
ITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPF
EEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCEECCCCCCCEEEEEEEEECCH
SEFKHNFNPENTKN
HHHHCCCCCCCCCC
>Mature Secondary Structure 
SKLKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEEEECC
GLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDY
CCCCCCEEEEEECCCHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCEEEEEEEECCCCE
ITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPF
EEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCEECCCCCCCEEEEEEEEECCH
SEFKHNFNPENTKN
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA