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The map label for this gene is csd

Identifier: 57651606

GI number: 57651606

Start: 923524

End: 924765

Strand: Direct

Name: csd

Synonym: SACOL0916

Alternate gene names: 57651606

Gene position: 923524-924765 (Clockwise)

Preceding gene: 57651605

Following gene: 57651607

Centisome position: 32.87

GC content: 37.28

Gene sequence:

>1242_bases
GTGGCCGAACACTCATTTGACGTTAATGAAGTAATCAAGGATTTTCCGATATTAGATCAAAAAGTCAATGGCAAACGTTT
AGCATATCTTGATTCAACAGCGACAAGTCAAACGCCTGTGCAAGTGTTAAATGTTTTAGAAGATTACTACAAGCGTTATA
ATTCAAACGTTCATCGTGGTGTTCATACATTAGGATCATTGGCAACTGATGGTTATGAAAATGCCCGTGAAACCGTTCGT
CGTTTTATTAATGCGAAGTATTTTGAAGAAATCATTTTTACACGCGGAACAACTGCGTCGATTAACCTTGTAGCACATAG
CTATGGTGATGCAAATGTTGAAGAGGGCGATGAAATTGTTGTCACTGAAATGGAACATCATGCCAATATTGTTCCTTGGC
AACAGTTAGCAAAGCGTAAAAATGCGACATTGAAATTTATACCAATGACAGCTGACGGTGAATTAAACATCGAGGATATT
AAGCAAACGATTAATGATAAAACAAAGATCGTTGCTATTGCACATATATCTAATGTGCTCGGTACAATTAATGATGTTAA
AACCATTGCAGAAATAGCTCATCAACATGGTGCAATTATCAGTGTTGATGGGGCGCAAGCAGCACCACATATGAAACTTG
ATATGCAAGAAATGAATGCTGATTTTTATAGTTTTAGTGGTCATAAAATGCTTGGACCAACAGGTATTGGCGTATTATTT
GGTAAACGTGAGTTACTACAAAAAATGGAACCGATTGAGTTCGGTGGCGACATGATTGATTTTGTAAGTAAGTATGATGC
AACATGGGCTGATTTACCTACTAAATTTGAGGCGGGTACTCCATTAATTGCTCAAGCAATTGGGCTTGCAGAAGCTATTC
GCTATTTAGAACGCATAGGTTTTGATGCAATTCATAAATATGAACAAGAATTAACGATATATGCTTATGAGCAAATGTCT
GCAATTGAAGGAATTGAAATTTATGGCCCGCCAAAGGATCGTCGTGCAGGTGTAATAACGTTTAATTTACAAGATGTACA
TCCACACGATGTTGCTACAGCCGTAGATACAGAAGGTGTAGCGGTTAGAGCTGGGCATCATTGTGCGCAACCGTTAATGA
AATGGTTAAATGTGTCTTCAACAGCTAGAGCGAGTTTTTATATATACAACACGAAAGAAGACGTTGATCAGTTAATAAAT
GCCTTGAAACAAACGAAGGAGTTTTTCTCTTATGAATTTTAA

Upstream 100 bases:

>100_bases
AAGTTTGTAATAGATATAGACTGTCGATATTGGTATAAGACTAATACAACGTCAGTATTTAAATGATTAGGATTTTTATT
TAAGAAAGGTCGTGAATGAA

Downstream 100 bases:

>100_bases
TAATCTAGATCAATTATATAGATCTGTCATTATGGATCATTATAAAAATCCTAGAAATAAAGGTGTATTAGATAACGGGT
CTATGACAGTAGATATGAAT

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVR
RFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDI
KQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLF
GKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMS
AIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLIN
ALKQTKEFFSYEF

Sequences:

>Translated_413_residues
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVR
RFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDI
KQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLF
GKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMS
AIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLIN
ALKQTKEFFSYEF
>Mature_412_residues
AEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRR
FINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIK
QTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFG
KRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSA
IEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINA
LKQTKEFFSYEF

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily

Homologues:

Organism=Homo sapiens, GI32307132, Length=400, Percent_Identity=23.75, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI156713448, Length=262, Percent_Identity=25.9541984732824, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787970, Length=405, Percent_Identity=48.1481481481481, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1789175, Length=381, Percent_Identity=39.3700787401575, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI48994898, Length=268, Percent_Identity=26.4925373134328, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=432, Percent_Identity=24.7685185185185, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI25143064, Length=278, Percent_Identity=27.3381294964029, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319831, Length=400, Percent_Identity=25.75, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI20129463, Length=246, Percent_Identity=31.3008130081301, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CSD_STAAC (Q5HHH0)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_185787.1
- ProteinModelPortal:   Q5HHH0
- SMR:   Q5HHH0
- STRING:   Q5HHH0
- EnsemblBacteria:   EBSTAT00000010964
- GeneID:   3237762
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL0916
- TIGR:   SACOL0916
- eggNOG:   COG0520
- GeneTree:   EBGT00050000024757
- HOGENOM:   HBG635316
- OMA:   YDSTWKE
- ProtClustDB:   CLSK884944
- BioCyc:   SAUR93062:SACOL0916-MONOMER
- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR01979

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.8.1.7

Molecular weight: Translated: 46277; Mature: 46146

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: ACT_SITE 368-368

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRG
CCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHH
VHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEE
VTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVL
EEEHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHHHH
GTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLF
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEHHHHCCCCEECCCCEEECCCCCHHHC
GKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIG
CHHHHHHHCCCCCCCCHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
FDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGV
HHHHHHHHHHEEEEEHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHCCCCCE
AVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF
EEECCHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRG
CCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHH
VHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEE
VTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVL
EEEHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHHHH
GTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLF
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEHHHHCCCCEECCCCEEECCCCCHHHC
GKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIG
CHHHHHHHCCCCCCCCHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
FDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGV
HHHHHHHHHHEEEEEHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHCCCCCE
AVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF
EEECCHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA