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The map label for this gene is nutA [H]

Identifier: 57651132

GI number: 57651132

Start: 31026

End: 33344

Strand: Direct

Name: nutA [H]

Synonym: SACOL0024

Alternate gene names: 57651132

Gene position: 31026-33344 (Clockwise)

Preceding gene: 57651131

Following gene: 57651134

Centisome position: 1.1

GC content: 38.68

Gene sequence:

>2319_bases
ATGAAAGCTTTATTACTTAAAACAAGTGTATGGCTCGTTTTGCTTTTTAGTGTAATGGGATTATGGCAAGTCTCGAACGC
GGCTGAGCAGCATACACCAATGAAAGCACATGCAGTAACAACGATAGACAAAGCAACAACAGATAAGCAACAAGTACCGC
CAACAAAGGAAGCGGCTCATCATTCTGGCAAAGAAGCGGCAACCAACGTATCAGCATCAGCGCAGGGAACAGCTGATGAT
ACAAACAGCAAAGTAACATCCAACGCACCATCTAACAAACCATCTACAGTAGTTTCAACAAAAGTAAACGAAACACGCGA
CGTAGATACACAACAAGCCTCAACACAAAAACCAACTCACACAGCAACGTTCAAATTATCAAATGCTAAAACAGCATCAC
TTTCACCACGAATGTTTGCTGCTAATGCACCACAAACAACAACACATAAAATATTACATACAAATGATATCCATGGCCGA
CTAGCCGAAGAAAAAGGGCGTGTCATCGGTATGGCTAAATTAAAAACAGTAAAAGAACAAGAAAAGCCTGATTTAATGTT
AGACGCAGGAGACGCCTTCCAAGGTTTACCACTTTCAAACCAGTCTAAAGGTGAAGAAATGGCTAAAGCAATGAATGCAG
TAGGTTATGATGCTATGGCAGTCGGTAACCATGAATTTGACTTTGGATACGATCAGTTGAAAAAGTTAGAGGGTATGTTA
GACTTCCCGATGCTAAGTACTAACGTTTATAAAGATGGAAAACGCGCGTTTAAGCCTTCAACGATTGTAACAAAAAATGG
TATTCGTTATGGAATTATTGGTGTAACGACACCAGAAACAAAGACGAAAACAAGACCTGAAGGCATTAAAGGCGTTGAAT
TTAGAGATCCATTACAAAGTGTGACAGCGGAAATGATGCGTATTTATAAAGACGTAGATACATTTGTTGTTATATCACAT
TTAGGAATTGATCCTTCAACACAAGAAACATGGCGTGGTGATTACTTAGTGAAACAATTAAGTCAAAATCCACAATTGAA
GAAACGTATTACAGTTATTGATGGTCATTCACATACAGTACTTCAAAATGGTCAAATTTATAACAATGATGCATTGGCAC
AAACAGGTACAGCACTTGCGAATATCGGTAAGATTACATTTAATTATCGCAATGGAGAGGTATCGAATATTAAACCGTCA
TTGATTAATGTTAAAGACGTTGAAAATGTAACACCGAACAAAGCATTAGCTGAACAAATTAATCAAGCTGATCAAACATT
TAGAGCACAAACTGCAGAGGTAATTATTCCAAACAATACCATTGATTTCAAAGGAGAAAGAGATGACGTTAGAACGCGTG
AAACAAATTTAGGAAACGCGATTGCAGATGCTATGGAAGCGTATGGCGTTAAGAATTTCTCTAAAAAGACTGACTTTGCC
GTGACAAATGGTGGAGGTATTCGTGCCTCTATCGCAAAAGGTAAGGTGACACGCTATGATTTAATCTCAGTATTACCATT
TGGAAATACGATTGCGCAAATTGATGTAAAAGGTTCAGACGTCTGGACGGCTTTCGAACATAGTTTAGGCGCACCAACAA
CACAAAAGGACGGTAAGACAGTGTTAACAGCGAATGGCGGTTTACTACATATCTCTGATTCAATCCGTGTTTACTATGAT
ATAAATAAACCGTCTGGCAAACGAATTAATGCTATTCAAATTTTAAATAAAGAGACAGGTAAGTTTGAAAATATTGATTT
AAAACGTGTATATCACGTAACGATGAATGACTTCACAGCATCAGGTGGCGACGGATATAGTATGTTCGGTGGTCCTAGAG
AAGAAGGTATTTCATTAGATCAAGTACTAGCAAGTTATTTAAAAACAGCTAACTTAGCTAAGTATGATACGACAGAACCA
CAACGTATGTTATTAGGTAAACCAGCAGTAAGTGAACAACCAGCTAAAGGACAACAAGGTAGCAAAGGTAGTAAGTCTGG
TAAAGATACACAACCAATTGGTGACGACAAAGTGATGGATCCAGCGAAAAAACCAGCTCCAGGTAAAGTTGTATTGTTGC
TAGCGCATAGAGGAACTGTTAGTAGCGGTACAGAAGGTTCTGGTCGCACAATAGAAGGAGCTACTGTATCAAGCAAGAGT
GGGAAACAATTGGCTAGAATGTCAGTGCCTAAAGGTAGCGCGCATGAGAAACAGTTACCAAAAACTGGAACTAATCAAAG
TTCAAGCCCAGAAGCGATGTTTGTATTATTAGCAGGTATAGGTTTAATCGCGACTGTACGACGTAGAAAAGCTAGCTAA

Upstream 100 bases:

>100_bases
ATATTAAATGTAATTTATAAATAATTTACATAAAATCAATCATTTTAATATAAGGATTATGATAATATATTGGTGTATGA
CAGTTAATGGAGGGAACGAA

Downstream 100 bases:

>100_bases
AATATATTGAAAATAATACTACTGTATTTCTTAAATAAGAGGTACGGTAGTGTTTTTTTATGAAAAAAAGCGATAACCGT
TGATAAATATGGGATATAAA

Product: 5'-nucleotidase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQHTPMKAHAVTTIDKATTDKQQVPPTKEAAHHSGKEAATNVSASAQGTADD
TNSKVTSNAPSNKPSTVVSTKVNETRDVDTQQASTQKPTHTATFKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTVKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKDVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
INKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSKSGKDTQPIGDDKVMDPAKKPAPGKVVLLLAHRGTVSSGTEGSGRTIEGATVSSKS
GKQLARMSVPKGSAHEKQLPKTGTNQSSSPEAMFVLLAGIGLIATVRRRKAS

Sequences:

>Translated_772_residues
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQHTPMKAHAVTTIDKATTDKQQVPPTKEAAHHSGKEAATNVSASAQGTADD
TNSKVTSNAPSNKPSTVVSTKVNETRDVDTQQASTQKPTHTATFKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTVKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKDVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
INKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSKSGKDTQPIGDDKVMDPAKKPAPGKVVLLLAHRGTVSSGTEGSGRTIEGATVSSKS
GKQLARMSVPKGSAHEKQLPKTGTNQSSSPEAMFVLLAGIGLIATVRRRKAS
>Mature_772_residues
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQHTPMKAHAVTTIDKATTDKQQVPPTKEAAHHSGKEAATNVSASAQGTADD
TNSKVTSNAPSNKPSTVVSTKVNETRDVDTQQASTQKPTHTATFKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTVKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKDVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
INKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSKSGKDTQPIGDDKVMDPAKKPAPGKVVLLLAHRGTVSSGTEGSGRTIEGATVSSKS
GKQLARMSVPKGSAHEKQLPKTGTNQSSSPEAMFVLLAGIGLIATVRRRKAS

Specific function: Degradation of extracellular 5'-nucleotides for nutritional needs [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=523, Percent_Identity=28.8718929254302, Blast_Score=156, Evalue=7e-38,
Organism=Escherichia coli, GI1786687, Length=551, Percent_Identity=27.9491833030853, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1790658, Length=264, Percent_Identity=26.5151515151515, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19922446, Length=498, Percent_Identity=26.9076305220884, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24654424, Length=498, Percent_Identity=26.9076305220884, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573524, Length=554, Percent_Identity=24.7292418772563, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI19922444, Length=600, Percent_Identity=25.8333333333333, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641187, Length=534, Percent_Identity=27.1535580524345, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI161076508, Length=478, Percent_Identity=26.1506276150628, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24652512, Length=478, Percent_Identity=26.1506276150628, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19921980, Length=478, Percent_Identity=26.1506276150628, Blast_Score=111, Evalue=2e-24,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 83425; Mature: 83425

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50847 GRAM_POS_ANCHORING ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQHTPMKAHAVTTIDKATTDKQQVPPTKEAAH
CCEEEEHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHEEEEEHHCCCCCCCCCCCHHHHH
HSGKEAATNVSASAQGTADDTNSKVTSNAPSNKPSTVVSTKVNETRDVDTQQASTQKPTH
CCCCHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCC
TATFKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGRLAEEKGRVIGMAKLKTVKEQ
EEEEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHCCCEEEHHHHHHHHHC
EKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCC
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQS
CCCCCCCHHHHCCHHHCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
VTAEMMRIYKDVDTFVVISHLGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTV
HHHHHHHHHHHHHHEEEEEECCCCCCCCHHHCHHHHHHHHHCCCCCEEEEEEEECCCEEE
LQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPSLINVKDVENVTPNKALAEQI
EECCEEECCCCHHHCCHHHHCCCEEEEEECCCCCCCCCCCEEEEHHCCCCCCCHHHHHHH
NQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
HHHHHHHHHCCEEEEECCCEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEE
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKT
EECCCCEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCEEHHHHHHCCCCCCCCCCCE
VLTANGGLLHISDSIRVYYDINKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTA
EEEECCCEEEEECCEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEECCEEC
SGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEPQRMLLGKPAVSEQPAKGQQG
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
SKGSKSGKDTQPIGDDKVMDPAKKPAPGKVVLLLAHRGTVSSGTEGSGRTIEGATVSSKS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCEECCCC
GKQLARMSVPKGSAHEKQLPKTGTNQSSSPEAMFVLLAGIGLIATVRRRKAS
CHHHHHHCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQHTPMKAHAVTTIDKATTDKQQVPPTKEAAH
CCEEEEHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHEEEEEHHCCCCCCCCCCCHHHHH
HSGKEAATNVSASAQGTADDTNSKVTSNAPSNKPSTVVSTKVNETRDVDTQQASTQKPTH
CCCCHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCC
TATFKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGRLAEEKGRVIGMAKLKTVKEQ
EEEEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHCCCEEEHHHHHHHHHC
EKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCC
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQS
CCCCCCCHHHHCCHHHCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
VTAEMMRIYKDVDTFVVISHLGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTV
HHHHHHHHHHHHHHEEEEEECCCCCCCCHHHCHHHHHHHHHCCCCCEEEEEEEECCCEEE
LQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPSLINVKDVENVTPNKALAEQI
EECCEEECCCCHHHCCHHHHCCCEEEEEECCCCCCCCCCCEEEEHHCCCCCCCHHHHHHH
NQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
HHHHHHHHHCCEEEEECCCEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEE
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKT
EECCCCEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCEEHHHHHHCCCCCCCCCCCE
VLTANGGLLHISDSIRVYYDINKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTA
EEEECCCEEEEECCEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEECCEEC
SGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEPQRMLLGKPAVSEQPAKGQQG
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
SKGSKSGKDTQPIGDDKVMDPAKKPAPGKVVLLLAHRGTVSSGTEGSGRTIEGATVSSKS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCEECCCC
GKQLARMSVPKGSAHEKQLPKTGTNQSSSPEAMFVLLAGIGLIATVRRRKAS
CHHHHHHCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2016269; 12620739 [H]