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The map label for this gene is sarZ

Identifier: 57650930

GI number: 57650930

Start: 2443605

End: 2444051

Strand: Direct

Name: sarZ

Synonym: SACOL2384

Alternate gene names: 57650930

Gene position: 2443605-2444051 (Clockwise)

Preceding gene: 57650927

Following gene: 57650931

Centisome position: 86.98

GC content: 28.41

Gene sequence:

>447_bases
ATGTATGTAGAAAACAGCTATCTTAGCAAACAGTTGTGTTTTTTATTTTATGTTTCTTCAAAAGAAATAATTAAAAAATA
CACAAACTATCTTAAGGAATATGATTTAACCTATACTGGTTACATTGTTTTAATGGCGATTGAAAATGATGAAAAACTTA
ACATCAAAAAATTAGGTGAACGTGTGTTCTTAGATTCTGGAACACTGACACCATTACTAAAGAAATTAGAAAAGAAAGAT
TACGTTGTTCGAACACGTGAAGAGAAAGATGAAAGAAACCTACAAATTTCTCTAACAGAACAAGGTAAAGCAATAAAAAG
CCCTCTTGCTGAAATTTCTGTTAAGGTCTTTAATGAATTCAACATTTCAGAACGAGAAGCATCAGATATAATTAATAATT
TGCGGAATTTTGTTTCTAAAAATTTTGACTATTCCGACAAAAAATAA

Upstream 100 bases:

>100_bases
ATTTAAATTCAATTATAGACAATTCAATAATTGCGATGAAATCAGTACTTGACAACTATTACACTTCATAATATTGTTTA
TTTTAACAAGGAGTGATTGG

Downstream 100 bases:

>100_bases
CTCCCTATCATAAGGTGATGGGCAGAAGTATGCATCGATATGTTTATTCATTATCTTTATTGCTTGTATAAATCTCGATG
CTCAGTTCTTTTGCCCTGAT

Product: accessory protein Z

Products: NA

Alternate protein names: Staphylococcal accessory regulator Z

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKD
YVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDKK

Sequences:

>Translated_148_residues
MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKD
YVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDKK
>Mature_148_residues
MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKD
YVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDKK

Specific function: Activates transcription of virulence factors alpha- and beta hemolysin genes (hla and hlb). Also, activates RNAIII expression, a central regulator transcribed from the agr locus

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SARZ_STAA3 (Q2FEB2)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494966.1
- ProteinModelPortal:   Q2FEB2
- SMR:   Q2FEB2
- STRING:   Q2FEB2
- EnsemblBacteria:   EBSTAT00000036680
- GeneID:   3913511
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_2331
- eggNOG:   COG1846
- GeneTree:   EBGT00050000024454
- HOGENOM:   HBG728159
- OMA:   YAASREI
- ProtClustDB:   CLSK885944
- GO:   GO:0005737
- GO:   GO:0009405
- InterPro:   IPR000835
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00598
- SMART:   SM00347

Pfam domain/function: PF01047 MarR

EC number: NA

Molecular weight: Translated: 17435; Mature: 17435

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS01117 HTH_MARR_1; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGE
CCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCHHHHCC
RVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEF
CCEECCCCHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCHHHCHHHHHHHHHHHCC
NISEREASDIINNLRNFVSKNFDYSDKK
CCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGE
CCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCHHHHCC
RVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEF
CCEECCCCHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCHHHCHHHHHHHHHHHCC
NISEREASDIINNLRNFVSKNFDYSDKK
CCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA