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The map label for this gene is yggV [C]

Identifier: 57650261

GI number: 57650261

Start: 1172626

End: 1173213

Strand: Direct

Name: yggV [C]

Synonym: SACOL1162

Alternate gene names: 57650261

Gene position: 1172626-1173213 (Clockwise)

Preceding gene: 57650260

Following gene: 57650262

Centisome position: 41.74

GC content: 32.99

Gene sequence:

>588_bases
ATGAAAGAGATTGTTATTGCATCGAATAATCAAGGGAAAATAAATGACTTTAAAGTAATATTTCCAGATTACCACGTAAT
AGGTATTTCAGAACTAATACCAGATTTTGATGTGGAAGAAACAGGATCAACATTTGAAGAAAATGCTATATTAAAATCAG
AAGCTGCTGCAAAAGCATTGAATAAAACGGTCATAGCTGATGACAGTGGACTAGAAGTTTTTGCATTAAATGGTGAGCCA
GGTATATACTCTGCACGTTATGCTGGTGAAAATAAAAGCGATGAAGCAAATATTGAAAAATTATTAAATAAGCTTGGTAA
TACAACTGATCGTCGTGCGCAATTTGTTTGTGTCATAAGTATGAGTGGCCCTGATATGGAAACAAAAGTATTTAAAGGTA
CTGTTTCAGGTGAAATTGCAGATGGAAAATATGGCGAAAATGGTTTCGGATATGATCCGATATTTTATGTACCGAAATTA
GATAAAACCATGGCTCAACTTTCAAAAGAACAAAAAGGGCAAATTAGTCATAGACGAAATGCGATTAATTTACTTCAAGC
TTTTCTTGAAGGTGATAAAAATGTCTAA

Upstream 100 bases:

>100_bases
CAACAGGTGATCCTACTCACATTACTAACATTATCAAAGAGTGGTTAAATTTATCTGTCAATGTGGAACGTATATCAGTG
AATGACTAGGAGGATTTTTA

Downstream 100 bases:

>100_bases
ATGGATTATTGTGAGTGATAACCATACTGAATCAGGCGTTTTATATCAAATTTATGAAATGCACCCAGATGCAGATGTAT
ATTTACATTTAGGAGATTCA

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEP
GIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKL
DKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV

Sequences:

>Translated_195_residues
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEP
GIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKL
DKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV
>Mature_195_residues
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEP
GIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKL
DKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789324, Length=191, Percent_Identity=43.979057591623, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17556833, Length=191, Percent_Identity=27.2251308900524, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920712, Length=191, Percent_Identity=32.4607329842932, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_STAAC (Q5HGT2)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186025.1
- ProteinModelPortal:   Q5HGT2
- SMR:   Q5HGT2
- STRING:   Q5HGT2
- EnsemblBacteria:   EBSTAT00000009211
- GeneID:   3238373
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1162
- TIGR:   SACOL1162
- eggNOG:   COG0127
- GeneTree:   EBGT00050000025430
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- ProtClustDB:   PRK14822
- BioCyc:   SAUR93062:SACOL1162-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21403; Mature: 21403

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKAL
CCEEEEEECCCCCCCEEEEECCCEEEEEHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHH
NKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVIS
CCEEEECCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEE
MSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRN
CCCCCCCCEEEECCCCCEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
AINLLQAFLEGDKNV
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKAL
CCEEEEEECCCCCCCEEEEECCCEEEEEHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHH
NKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVIS
CCEEEECCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEE
MSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRN
CCCCCCCCEEEECCCCCEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
AINLLQAFLEGDKNV
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA