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The map label for this gene is relA1 [H]

Identifier: 57650198

GI number: 57650198

Start: 1017791

End: 1018426

Strand: Direct

Name: relA1 [H]

Synonym: SACOL1010

Alternate gene names: 57650198

Gene position: 1017791-1018426 (Clockwise)

Preceding gene: 57650197

Following gene: 57650199

Centisome position: 36.23

GC content: 33.65

Gene sequence:

>636_bases
ATGAATCAATGGGATCAGTTCTTAACACCTTATAAGCAAGCGGTTGATGAGTTGAAAGTGAAACTTAAAGGCATGCGCAA
ACAATATGAAGTTGGTGAACAAGCGTCGCCAATAGAATTTGTTACTGGTCGTGTTAAACCAATCGCTAGTATTATAGATA
AGGCAAACAAACGACAAATACCATTTGATAGGTTAAGAGAAGAAATGTACGATATCGCTGGTTTAAGAATGATGTGCCAA
TTTGTTGAAGATATTGATGTTGTCGTCAATATTTTAAGACAAAGAAAAGATTTTAAAGTAATTGAAGAACGAGATTATAT
TCGTAACACTAAAGAAAGTGGTTACCGCTCGTATCATGTCATTATTGAATATCCAATTGAAACATTACAAGGCCAAAAAT
TTATATTGGCTGAGATTCAGATTCGTACATTAGCAATGAATTTCTGGGCAACGATTGAACATACTTTACGATATAAATAT
GATGGTGCTTATCCGGATGAAATTCAACATCGTTTGGAAAGAGCGGCAGAAGCAGCGTATTTACTTGATGAAGAGATGTC
TGAAATTAAAGATGAAATTCAGGAAGCTCAAAAATATTACACGCAAAAACGTTCTAAAAAACATGAAAATGATTAA

Upstream 100 bases:

>100_bases
TATATTTTAGACAACATAAAAGGGAATAATAATTATGGTAAGGAATTTGTTGCAACCGTTGAAGAAACATTCGACATTGA
ATAAAGCGGGGTGAAGCACT

Downstream 100 bases:

>100_bases
CGAGGTGTTATAAATCATGCGTTATACAATTTTAACTAAAGGTGACTCCAAGTCTAATGCCTTAAAGCATAAAATGATGA
ACTATATGAAAGATTTTCGC

Product: GTP pyrophosphokinase

Products: NA

Alternate protein names: (p)ppGpp synthase yjbM; Small alarmone synthase 1; SAS 1 [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MNQWDQFLTPYKQAVDELKVKLKGMRKQYEVGEQASPIEFVTGRVKPIASIIDKANKRQIPFDRLREEMYDIAGLRMMCQ
FVEDIDVVVNILRQRKDFKVIEERDYIRNTKESGYRSYHVIIEYPIETLQGQKFILAEIQIRTLAMNFWATIEHTLRYKY
DGAYPDEIQHRLERAAEAAYLLDEEMSEIKDEIQEAQKYYTQKRSKKHEND

Sequences:

>Translated_211_residues
MNQWDQFLTPYKQAVDELKVKLKGMRKQYEVGEQASPIEFVTGRVKPIASIIDKANKRQIPFDRLREEMYDIAGLRMMCQ
FVEDIDVVVNILRQRKDFKVIEERDYIRNTKESGYRSYHVIIEYPIETLQGQKFILAEIQIRTLAMNFWATIEHTLRYKY
DGAYPDEIQHRLERAAEAAYLLDEEMSEIKDEIQEAQKYYTQKRSKKHEND
>Mature_211_residues
MNQWDQFLTPYKQAVDELKVKLKGMRKQYEVGEQASPIEFVTGRVKPIASIIDKANKRQIPFDRLREEMYDIAGLRMMCQ
FVEDIDVVVNILRQRKDFKVIEERDYIRNTKESGYRSYHVIIEYPIETLQGQKFILAEIQIRTLAMNFWATIEHTLRYKY
DGAYPDEIQHRLERAAEAAYLLDEEMSEIKDEIQEAQKYYTQKRSKKHEND

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the relA/spoT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007685 [H]

Pfam domain/function: PF04607 RelA_SpoT [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 25239; Mature: 25239

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQWDQFLTPYKQAVDELKVKLKGMRKQYEVGEQASPIEFVTGRVKPIASIIDKANKRQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCCCC
PFDRLREEMYDIAGLRMMCQFVEDIDVVVNILRQRKDFKVIEERDYIRNTKESGYRSYHV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEE
IIEYPIETLQGQKFILAEIQIRTLAMNFWATIEHTLRYKYDGAYPDEIQHRLERAAEAAY
EEECCHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLDEEMSEIKDEIQEAQKYYTQKRSKKHEND
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNQWDQFLTPYKQAVDELKVKLKGMRKQYEVGEQASPIEFVTGRVKPIASIIDKANKRQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCCCC
PFDRLREEMYDIAGLRMMCQFVEDIDVVVNILRQRKDFKVIEERDYIRNTKESGYRSYHV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEE
IIEYPIETLQGQKFILAEIQIRTLAMNFWATIEHTLRYKYDGAYPDEIQHRLERAAEAAY
EEECCHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLDEEMSEIKDEIQEAQKYYTQKRSKKHEND
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]